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Study finds nirmatrelvir-ritonavir reduces severe COVID-19 and long COVID risks in high-risk patients

Nirmatrelvir-ritonavir effectively lowers hospitalization rates and long COVID symptoms in non-hospitalized, high-risk patients with mild to moderate COVID-19.

30 Oct 2024

New antibody platform targets evolving viruses

Scientists at the Icahn School of Medicine at Mount Sinai, in collaboration with colleagues in the field, have developed an innovative antibody platform aimed at tackling one of the greatest challenges in treating rapidly evolving viruses like SARS-CoV-2: their ability to mutate and evade existing vaccines and therapies.

23 Oct 2024

Trial evaluates monoclonal antibodies for long COVID prevention

The first randomized, placebo-controlled clinical trial evaluating the impact of therapeutic monoclonal antibodies on the risk of developing long COVID was led by researchers at Weill Cornell Medicine.

17 Oct 2024

Study shows no developmental delays in toddlers post-COVID-19 infection

Study explored the relationship between SARS-CoV-2 infection in children under two years old and cognitive development, finding no evidence of increased developmental delays post-infection. Differences in socioeconomic status were noted between COVID-19 positive and negative groups.

15 Oct 2024

COVID-19 testing and variants more prevalent in minority communities

More than four years after the COVID-19 pandemic caused the world to come to a standstill, lessons in pandemic response are still being learned. What we know: the global pandemic disproportionately affected racial and ethnic minority groups across the U.S., with Black and Hispanic individuals being three to four times more likely to die from COVID compared to white individuals.

10 Oct 2024

Antigenic mapping sheds light on SARS-CoV-2 immunity differences

A person's immune response to variants of SARS-CoV-2, the virus that causes COVID-19, depends on their previous exposure - and differences in the focus of immune responses will help scientists understand how to optimise vaccines in the future to provide broad protection.

7 Oct 2024

COVID-19 increases chronic fatigue risk

Study reveals that COVID-19 significantly increases the risk of chronic fatigue syndrome, with specific populations, such as older adults, Asians, and non-hospitalized patients, at higher risk.

7 Oct 2024

Long COVID affects 38% of emergency patients with persistent symptoms

Researchers found that post-COVID-19 condition (PCC) symptoms persist in a significant number of both SARS-CoV-2 positive and negative emergency department patients, highlighting the non-specific nature of the WHO’s PCC criteria.

1 Oct 2024

Study reveals widespread long-COVID symptoms, challenging WHO definition

Study reveals that more than one-third of SARS-CoV-2 positive patients experience long-COVID symptoms three months after an emergency department visit, with significant overlap in symptoms observed among negative patients.

1 Oct 2024

How viral persistence and immune dysfunction drive long COVID

Study explores the biological drivers and mechanisms of long COVID, shedding light on its epidemiology and potential therapeutic interventions. It emphasizes the role of viral persistence, immune dysfunction, and coagulation in the development of this condition.

29 Sep 2024

Antiviral drug molnupiravir linked to new mutations in SARS-CoV-2

Molnupiravir, an antiviral drug used to treat patients with COVID-19, appears to be driving SARS-CoV-2 to mutate and evolve, with some of these new viruses being transmitted onwards, a new study has shown.

26 Sep 2024

Florida’s new covid booster guidance is straight-up misinformation

In what has become a pattern of spreading vaccine misinformation, the Florida health department is telling older Floridians and others at highest risk from covid-19 to avoid most booster shots, saying they are potentially dangerous.

23 Sep 2024

Researchers identify new oscillatory patterns in COVID-19 cases across the U.S.

Researchers discovered previously unrecognized oscillatory trends in COVID-19 cases across the U.S., particularly a north-south oscillation around the 37°-38° north latitude. These patterns highlight the complexity of pandemic dynamics and the importance of understanding regional disease transmission.

22 Sep 2024

Artificial lymphoid organ-chips created to predict vaccine responses in humans

Researchers at the Institut Pasteur in France have developed artificial "lymphoid organ-chips" that recreate much of the human immune system's response to booster vaccines

6 Sep 2024

Mucosal COVID-19 boosters outperform mRNA shots in preventing upper airway infections

Aerosolized mucosal vaccines show promise in controlling SARS-CoV-2, offering greater protection and immune response than intramuscular bivalent mRNA boosters.

5 Sep 2024

Early viral activity plays critical role in long COVID, study suggests

Findings on early viral and immune markers provide insights into the pathogenesis of post-acute sequelae of SARS-CoV-2, informing future research and therapies.

2 Sep 2024

Intranasal vaccine shows broad SARS-CoV-2 variant protection

Study demonstrates that a single-dose intranasal live-attenuated vaccine, CDO-7N-1, provides broad protection against SARS-CoV-2 and its variants by inducing potent immune responses, including neutralizing antibodies and T-cell activity, in animal models.

1 Sep 2024

Analysis reveals viral shift behind COVID-19 pandemic end

New analysis suggests that a dramatic drop in deaths from COVID-19 between 2022 and 2023 could be attributed to an abrupt phase transition in the molecular structure of the virus' spike protein.

28 Aug 2024

Dengue increases risk of heart and neurological complications compared to COVID-19

People who caught dengue and recovered are more likely to face long-term health complications about a year later compared to those who contracted COVID-19, according to the findings of a nationwide study led by Nanyang Technological University, Singapore (NTU Singapore).

27 Aug 2024

The new covid vaccine is out. Why you might not want to rush to get it.

The FDA has approved an updated covid shot for everyone 6 months old and up, which renews a now-annual quandary for Americans: Get the shot now, with the latest covid outbreak sweeping the country, or hold it in reserve for the winter wave?

26 Aug 2024