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African production of mpox vaccines could secure the continent’s health

As Africa grapples with multiple outbreaks of mpox, public health leaders say locally produced vaccines are vital to end donation dependence and secure the continent's health.

29 Oct 2024

Scurvy may be making a comeback amid economic strain

The scourge of scurvy, which is caused by vitamin C deficiency, may be re-emerging amid the cost of living crisis and the rise in weight loss (bariatric) surgery, suggest doctors in the journal BMJ Case Reports after treating a middle-aged man with the condition.

22 Oct 2024

Long-term low-dose antiviral treatment reduces eye disease risk from shingles

Long-term, low-dose antiviral treatment reduces the risk for potentially vision-damaging bouts of inflammation and infection, as well as pain, which occur when shingles affects the eye, according to new research presented October 19 at the annual meeting of the American Academy of Ophthalmology (AAO) in Chicago.

20 Oct 2024

New combination treatment authorized for unresectable urothelial cancer patients

Astellas Pharma Ltd. today announced that the Medicines and Healthcare products Regulatory Agency (MHRA) has granted authorization for PADCEV™ (enfortumab vedotin, an antibody-drug conjugate [ADC]) in combination with KEYTRUDA® (pembrolizumab, a PD-1 inhibitor) for the first-line treatment of adult patients with unresectable or metastatic urothelial cancer, who are eligible for platinum-containing chemotherapy.

18 Oct 2024

A review of clinical features, diagnosis, and management of Mpox

A comprehensive review in JAMA outlines monkeypox's clinical presentation and management, stressing the need for increased surveillance and vaccination efforts.

17 Oct 2024

Groundbreaking discovery offers hope for patients suffering from toxic epidermal necrolysis

A global team of researchers at the Max Planck Institute of Biochemistry has made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis.

16 Oct 2024

New insights into pain mechanisms related to viral infections

An article published in the journal Brain, Behavior, and Immunity reports the findings of a study by researchers based in Brazil, the United States and South Korea who set out to understand how viral infections cause pain and to contribute to the search for novel ways of relieving it.

15 Oct 2024

Study warns of increasing Rocky Mountain spotted fever cases among children in California

Recent cases of Rocky Mountain spotted fever in children underscore the effectiveness of mcf-NGS for early detection and timely treatment in non-endemic areas.

15 Oct 2024

Scientists detect replication-competent Oropouche virus in semen of traveler, sparking transmission fears

Researchers confirmed the presence of replication-competent Oropouche virus in semen, raising concerns about potential sexual transmission following a traveler's infection.

9 Oct 2024

Increasing cases of mosquito-borne diseases call for greater awareness

The hospitalization last summer of Dr. Anthony Fauci, former head of the National Institute of Allergy and Infectious Diseases, with West Nile virus – and his account of it this week in the New York Times – have helped raise public awareness of the dangers of mosquito borne-illness, which can range from Zika and malaria to dengue and West Nile virus.

8 Oct 2024

WHO lists first mpox in vitro diagnostic test under Emergency Use Listing

The World Health Organization (WHO) has listed the first mpox in vitro diagnostic (IVD) under its Emergency Use Listing (EUL) procedure, an important step in improving global access to mpox testing.

4 Oct 2024

High impulsivity linked to increased stress response during boring tasks

Research at the University of Portsmouth has explored the relationship between high impulsivity and boredom, in an effort to find out what drives rash and sometimes unhealthy decisions.

26 Sep 2024

Epidemiology of viral pathogens involved in febrile rash illness

Announcing a new article publication for Zoonoses journal. The aim of this study was to monitor the spectrum of viral pathogens involved in febrile rash illness (FRI) and their epidemiology.

23 Sep 2024

Multiple myeloma drug shows efficacy in treating rare bleeding disorder

A drug approved for treating the blood cancer multiple myeloma may offer a safe and effective way to reduce the risk of severe nosebleeds from a rare but devastating bleeding disorder.

19 Sep 2024

Innovative triplet therapy shows encouraging results in advanced chronic myeloid leukemia

According to researchers at The University of Texas MD Anderson Cancer Center, 80% of patients with previously untreated or relapsed/refractory advanced-phase chronic myeloid leukemia (CML) – including both accelerated or myeloid blast phases of the disease – or Philadelphia chromosome-positive acute myeloid leukemia (AML) achieved a bone marrow remission when treated with a novel combination of decitabine, venetoclax and ponatinib.

17 Sep 2024

Zongertinib shows promising efficacy in HER2 mutation-positive NSCLC

The HER2-specific tyrosine kinase inhibitor zongertinib was well tolerated and demonstrated promising efficacy in patients with HER2 mutation-positive non-small cell lung cancer, meeting the primary endpoint of the Beamion LUNG-1 Phase Ib Cohort 1 study, according to research presented today at the International Association for the Study of Lung Cancer 2024 World Conference on Lung Cancer.

11 Sep 2024

Cell-free RNA analysis enhances early detection of pediatric inflammatory conditions

RNA is expelled from cells via cell death or active release, and can then find its way into blood plasma. A Cornell University-led collaboration has developed machine learning models that use these cell-free molecular RNA dregs to diagnose pediatric inflammatory conditions that are difficult to differentiate.

9 Sep 2024

Mpox inactivated in 60 seconds with Σ-MM™ & patient friendly collection swab

In the wake of the global Mpox outbreak in non-endemic countries in 2022, the medical community has been searching for safer and more efficient ways to transport and test virus samples, especially from patients in areas with limited biological containment facilities.

From Medical Wire 6 Sep 2024

Study identifies key predictors of severe mpox cases

The study uncovers factors influencing mpox severity and duration, emphasizing the role of viral load and specific clinical presentations in patient outcomes.

2 Sep 2024

Nigeria and DRC take action with new mpox vaccine rollouts

Nigeria is to begin the immediate rollout of 5,000 doses of mpox vaccines while the Democratic Republic of Congo (DRC) eyes its first shipment of 65,000 doses, as Africa steps up measures to control the multi-country outbreak.

30 Aug 2024