Rat Model News and Research

RSS

Researchers discover key biochemical mechanism in Huntington's disease development

Researchers from the University of Oxford have identified a key biochemical mechanism relevant to the development of Huntington's Disease.

28 Oct 2024

Fish oil speeds muscle recovery in aging rats, suggesting potential benefits for humans

Fish oil supplementation improves muscle recovery in aged rats and enhances membrane repair in muscle cells, suggesting potential benefits for aging-related muscle injuries.

21 Oct 2024

New ultrasound-based tool offers precise measurement of lung diseases

Researchers have established a suite of parameters that can be determined using ultrasound to quantitatively measure different physical characteristics of the lung.

13 Aug 2024

New omega-3 therapy shows promise in treating newborn brain injuries

A novel therapeutic approach for neonatal hypoxic-ischemic (HI) brain injury.

11 Jun 2024

New research finds no causal link between vitamin E levels and osteoarthritis

A recent study used Mendelian randomization to explore the link between osteoarthritis (OA) and alpha-tocopherol, a form of vitamin E, and found no evidence of a causal relationship between the two.

6 May 2024

Modified sugar molecules boost stem cell therapy for brain repair after cardiac arrest

Researchers at the University of Maryland School of Medicine (UMSOM) have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

6 May 2024

High-fat diet accelerates aging-related memory loss in rats

Study found that a high-fat diet exacerbates age-related cognitive decline in rats, even when microglia cells are removed from the equation, suggesting other pathways may play a role.

5 May 2024

Glycoengineered stem cells enhance brain recovery after cardiac arrest, study finds

Researchers at the University of Maryland School of Medicine have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

2 May 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Study highlights anti-inflammatory properties of herbal medicine, Erigeron breviscapus to treat osteoarthritis

Researchers explored using Erigeron breviscapus (EB) as a treatment for osteoarthritis (OA).

4 Apr 2024

Inhibiting neurons involved in the body's stress response may reduce alcohol use

Neuroscientists at Scripps Research have found that inhibiting neurons involved in the body's stress response may reduce alcohol consumption in people who have both post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD)-;even if they still experience trauma-related anxiety.

21 Mar 2024

Study demonstrates the deleterious effects of chronic cocaine use on functional brain networks

A collaborative research endeavor by scientists in the Departments of Radiology, Neurology, and Psychology and Neuroscience at the UNC School of Medicine have demonstrated the deleterious effects of chronic cocaine use on the functional networks in the brain.

28 Feb 2024

Mitochondrial activation enhances cardiac regeneration therapy

Regenerative therapy to treat heart failure is more effective when the mitochondria of the regenerative cells are activated prior to treatment.

21 Feb 2024

Extract from pomegranate peels and seeds shows anti-hypertensive properties

The efficacy of an extract obtained from the non-edible parts of pomegranates.

14 Feb 2024

Study provides insight into potential mechanisms underlying diabetes-related disc tissue damage

Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal.

13 Feb 2024

Sesame oil supplementation: a potential breakthrough in postmenopausal osteoporosis prevention?

Daily sesame oil supplementation in ovariectomized rats was found to prevent osteoporosis by enhancing bone formation, reducing bone resorption, and maintaining serum estrogen and aromatase levels.

7 Jan 2024

Unlocking the power of diet: How miRNAs influence health and disease

The role of dietary microRNAs (miRNAs) in health and disease.

5 Jan 2024

Prevention of post-menopausal osteoporosis in rats by sesame oil

Study demonstrates that daily supplementation with sesame oil in a rat model effectively prevents post-menopausal osteoporosis by maintaining serum estrogen and aromatase levels, suggesting its potential as a safer alternative to hormone replacement therapy.

4 Jan 2024

The potential of polyunsaturated fatty acids in alleviating depression and reducing suicide risk

Research in 'Molecular Psychiatry' explores the role of long-chain polyunsaturated fatty acids (LC-PUFAs) in major depressive disorder (MDD) and suicide risk, showing mixed results in clinical trials for depression treatment. The study underscores the need for further investigation into LC-PUFAs' neurobiology to advance personalized medicine for mood disorders and suicide prevention.

26 Nov 2023

Study shows why only a subset of individuals exposed to trauma develop PTSD

A study by researchers at EPFL shows why only a subset of individuals exposed to trauma develop posttraumatic stress disorder (PTSD).

7 Nov 2023