Aortic Aneurysm News and Research

RSS

Abdominal aortic aneurysm (AAA) is a ballooning of the aorta, the largest blood vessel in the human body, which extends into the abdomen. If the wall of this blood vessel becomes weakened, it can stretch, "balloon" out and rupture. A rupture, if left untreated, can lead to life-threatening internal bleeding. The exact cause of this condition is unknown. However, it often occurs in older adults, especially males, those with a high cholesterol level, and in smokers. There also tends to be a genetic link to this disorder.

Physics-informed AI framework improves aortic aneurysm stress prediction

Ascending thoracic aortic aneurysms often progress silently, but once dissection or rupture occurs, they can cause severe mortality before hospital arrival or during admission.

4 Sep 2026

New genetic risk report reveals hidden heart disease risk before symptoms appear

Researchers developed and externally validated integrated polygenic risk scores for eight cardiovascular conditions using large U.S.-based biobank data. The clinically orderable report may help identify inherited cardiovascular risk that traditional clinical markers can miss, although broader prospective validation is still needed.

30 Apr 2026

New genetic risk test estimates inherited risk for cardiovascular conditions

Researchers at Mass General Brigham Heart and Vascular Institute and collaborators have developed and validated a new genetic risk test that can estimate a person's inherited risk for eight common cardiovascular conditions, offering a more comprehensive approach to prevention.

29 Apr 2026

Common osteoporosis drugs could slow or halt aneurysm progression

Aortic aneurysms are characterized by abnormal enlargement of the aorta, the primary artery responsible for carrying blood from the heart. Rupture often leads to sudden death, and currently, no effective drug therapies are available to halt disease progression.

14 Apr 2026

Study explores how reversible RNA editing could transform future cardiovascular medicine

This mini-review synthesises evidence showing that adenosine-to-inosine RNA editing plays an important regulatory role in cardiovascular development, cellular homeostasis, and disease biology. It highlights emerging links between dysregulated RNA editing and cardiovascular conditions while outlining biomarker potential and reversible RNA-editing therapeutic strategies that remain under investigation.

15 Feb 2026

New initiative boosts surveillance imaging, cuts mortality after aortic aneurysm repair

Through a statewide partnership, hospitals in Michigan drastically increased the number of patients who receive follow up imaging after undergoing aortic aneurysm repair, according to a recent study.

19 Jan 2026

Postoperative geriatric syndromes signal high vulnerability and poor outcomes in older adults

Older adults who develop a new geriatric syndrome - such as dehydration, delirium, or malnutrition - after major surgery face a dramatically higher risk of poor outcomes, including more complications, fewer days spent at home, and a significantly increased likelihood of dying within a year, according to findings published in the Journal of the American College of Surgeons.

20 Nov 2025

New data supports earlier use of evolocumab in high-risk diabetes

Adding the PCSK9 inhibitor evolocumab to a high-intensity, cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with atherosclerotic cardiovascular disease (ASCVD) or diabetes , according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Heart attack in older adults linked to higher risk of late-onset epilepsy

Older adults who have a heart attack may be more likely to develop epilepsy later in life, according to a study published November 5, 2025 in Neurology®, the medical journal of the American Academy of Neurology.

5 Nov 2025

Study reveals how DKK3 triggers smooth muscle cell transformation in aortic aneurysm

Abdominal aortic aneurysm (AAA) is a life-threatening vascular disorder that primarily affects elderly males.

10 Oct 2025

Elevated TMAO levels linked to higher risk of abdominal aortic aneurysms

Cleveland Clinic researchers have discovered a connection between elevated blood levels of TMAO (trimethylamine N-oxide) - a byproduct of gut bacteria digestion of nutrients found in red meat and other animal products - and a higher risk of abdominal aortic aneurysms.

20 Aug 2025

Triglycerides identified as direct cause of abdominal aortic aneurysms

High levels of triglycerides, the most common type of fat in the body and the foods we eat, directly cause abdominal aortic aneurysms, according to a study in mouse models led by Michigan Medicine.

14 Aug 2025

Exploring the genetic link between COPD and abdominal aortic aneurysm

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Chronic obstructive pulmonary disease (COPD) and abdominal aortic aneurysm (AAA) are both severe conditions with complex etiologies and substantial comorbidities.

18 Jul 2025

Heart scan study reveals low-fiber diets drive dangerous heart plaques

A Swedish study links low-fiber, high-red meat diets to increased coronary artery plaque risk, highlighting the importance of dietary choices for heart health.

18 Jun 2025

EMA designates allopurinol as first orphan drug for the treatment of Marfan syndrome

The European Medicines Agency (EMA) has designated allopurinol as the first orphan drug for the treatment of Marfan syndrome, a rare connective tissue disease which as no cure to date.

19 May 2025

New biomarkers and therapeutic targets identified for abdominal aortic aneurysm

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This article aimed to identify molecular candidates to serve as diagnostic biomarkers and therapeutic targets for abdominal aortic aneurysm (AAA).

5 May 2025

New protein target offers hope for treating high blood pressure and aortic aneurysms

Oxidative stress can occur when our cells are exposed to harmful molecules called "reactive oxygen species" over time. These reactive oxygen species can damage cells and are found in important disease states, such as high blood pressure and aortic aneurysms.

30 Apr 2025

How added sugars and sweetened foods impact the risk of 7 cardiovascular diseases

Researchers examine the risk of seven different types of cardiovascular diseases associated with added and free sugar in foods and beverages.

12 Dec 2024

Study finds divergent relationship between different sugar sources and cardiovascular disease risk

A little of what you fancy does you good… unless it's a fizzy drink. Scientists studying the impact of sugar on the risk of cardiovascular disease have found that eating too much added sugar increases your risk of stroke or aneurysm, but eating a few treats is associated with a lower risk of cardiovascular diseases.

9 Dec 2024

Study: Obstructive sleep apnea may be a risk factor for abdominal aortic aneurysms

Obstructive sleep apnea may be a risk factor for developing abdominal aortic aneurysms, according to researchers from the University of Missouri School of Medicine and NextGen Precision Health.

25 Sep 2024