siRNA News and Research

RSS
Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA molecules, 20-25 nucleotides in length, that play a variety of roles in biology. Most notably, siRNA is involved in the RNA interference (RNAi) pathway, where it interferes with the expression of a specific gene. In addition to their role in the RNAi pathway, siRNAs also act in RNAi-related pathways, e.g., as an antiviral mechanism or in shaping the chromatin structure of a genome; the complexity of these pathways is only now being elucidated.
New nanoparticle system fights obesity

New nanoparticle system fights obesity

When CDK12/13 stalls, healthy prostate cells take a malignant turn

When CDK12/13 stalls, healthy prostate cells take a malignant turn

New chemical modification reduces off-target effects in siRNA drugs

New chemical modification reduces off-target effects in siRNA drugs

Exploring gene silencing mechanisms for improved RNAi therapeutics

Exploring gene silencing mechanisms for improved RNAi therapeutics

60 years in the making: Nanoparticles revolutionize nucleotide delivery

60 years in the making: Nanoparticles revolutionize nucleotide delivery

Agreement to explore Optimer vehicles for targeted delivery of siRNA

Agreement to explore Optimer vehicles for targeted delivery of siRNA

MPA-CF3: A marine-derived compound disrupting COPZ1 to combat EV-A71

MPA-CF3: A marine-derived compound disrupting COPZ1 to combat EV-A71

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

RNA-based therapy shows promise in reducing cholesterol and triglycerides

RNA-based therapy shows promise in reducing cholesterol and triglycerides

Young mouse plasma found to reverse aging in older mice

Young mouse plasma found to reverse aging in older mice

Adipose-derived stem cell exosomes play protective roles in mitigating myocardial injury

Adipose-derived stem cell exosomes play protective roles in mitigating myocardial injury

New model pinpoints drug interactions in the digestive tract

New model pinpoints drug interactions in the digestive tract

Researchers develop novel nanomedicine loaded with genetic material to fight  HIV

Researchers develop novel nanomedicine loaded with genetic material to fight HIV

Novel splicing mechanism for short introns discovered

Novel splicing mechanism for short introns discovered

MIT scientists develop nanoparticles to reduce inflammation in the brain

MIT scientists develop nanoparticles to reduce inflammation in the brain

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Silencing galectin 1 protein shrinks liver cancer tumors in mice

Study highlights YB-1 targeting as novel treatment approach for pleural mesothelioma

Study highlights YB-1 targeting as novel treatment approach for pleural mesothelioma

Discovery lead to better methods for reducing mosquito-to-human transmission of deadly viruses

Discovery lead to better methods for reducing mosquito-to-human transmission of deadly viruses

Unraveling the relationship between obesity-related metabolic dysfunction and endotrophin

Unraveling the relationship between obesity-related metabolic dysfunction and endotrophin

Study identifies potential target for reversing drug resistance in ovarian cancer

Study identifies potential target for reversing drug resistance in ovarian cancer

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.