The pain-reliever acetaminophen (also known as paracetomol) is one of the best-selling over-the-counter medications, used by more than 200 million Americans a year. It is sold under many brand names, including Tylenol, and is an ingredient in nearly 200 medications, both over-the-counter (such as Excedrin, Midol, NyQuil, and Sudafed) and prescription (such as Vicodin).
Results from a new study show that after an acetaminophen overdose the p53 protein plays a key role in preventing the progression of liver damage and signaling the liver to repair itself.
Twenty years ago, the federal government funded the study of a condition quietly killing hundreds of Americans a year - acute liver failure, or ALF. Growing evidence had linked ALF to overdoses of acetaminophen, the popular over-the-counter pain medication many viewed as harmless at the time.
Widely used pain relievers may increase the risk of a heart attack when used during a cold or flu-like illness, according to a new study published in the Journal of Infectious Diseases.
In a study to be presented Thursday, Jan. 26, in the oral concurrent session at 1:15 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, researchers with the Université de Sherbrooke in Sherbrooke, Quebec, Canada will present their findings in a study titled, Reduction of total labor length through the addition of parenteral dextrose solution in induction of labor in nulliparous: results of DEXTRONS prospective randomized controlled trial.
A team of Michigan State University researchers, led by James Luyendyk in the College of Veterinary Medicine, has uncovered a new pathway in the body that stimulates liver repair.
The U.S. Food and Drug Administration today expanded the approved use of Dexcom's G5 Mobile Continuous Glucose Monitoring System to allow for replacement of fingerstick blood glucose (sugar) testing for diabetes treatment decisions in people 2 years of age and older with diabetes.
Researchers from the University of South Carolina, Duke University, University of Alabama at Birmingham, and Metabolon Inc. Research Triangle Park have discovered a new pathway in the liver that opens the door to treat non-alcoholic fatty liver disease, a condition that affects up to 25 percent of the population and may lead to cirrhosis and eventually liver cancer or failure, and likely other liver diseases.
More than 1,000 medications, with acetaminophen being the most common, have been associated with drug-induced liver injury.
Researchers at Indiana University's Biocomplexity Institute have developed a virtual model of the human liver to better understand how the organ metabolizes acetaminophen, a common non-prescription painkiller and fever-reducer used in over-the-counter drugs such as Tylenol.
Men can take birth control shots to prevent pregnancy in their female partners, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
Osteoarthritis is a debilitating condition that affects at least 27 million people in the United States, and at least 12 percent of osteoarthritis cases stem from earlier injuries.
Protocols allowing nurses to administer certain types of treatment in the emergency department can dramatically shorten length of stay for patients with fever, chest pain, hip fractures and vaginal bleeding during pregnancy, according to the results of a study published earlier this month in Annals of Emergency Medicine.
WIn a study of children with mild, persistent asthma, scientists found that acetaminophen was tolerated without the worsening of asthma, when compared with ibuprofen use.
Neuropathic pain - which affects more than 1 million Americans - could be reduced or even eliminated by targeting brain cells that are supposed to provide immunity but, in some instances, do the opposite, causing chronic pain that could last a lifetime.
Chemists at The University of Texas at Arlington have invented a method to quantify water content in solid pharmaceutical drugs that is faster, cheaper, more accurate and more precise than Karl Fischer titration, the method currently recognized by the U.S. Food and Drug Administration and widely used worldwide.
As the eyes of the world turn to Rio de Janiero for the 2016 Summer Olympics, the spread of the Zika virus in Brazil is a growing concern — but Zika is not the only disease that mosquitoes can spread to humans.
The Alliance for Balanced Pain Management (AfBPM) made the following statement on the Obama administration’s plan to curb the opioid addiction crisis, which was released this morning as Congress prepares to tackle funding for related programs.
Fireworks can result in severe burns, scars and disfigurement that can last a lifetime.
A new study has found that paracetamol (acetaminophen), which is used extensively during pregnancy, has a strong association with autism spectrum symptoms in boys and for both genders in relation to attention-related and hyperactivity symptoms.
The natural molecule, n-acetylcysteine (NAC), with strong antioxidant effects, shows potential benefit as part of the management for patients with Parkinson's disease, according to a study published today in the journal PLOS ONE.