Acute Pain News and Research

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Next generation painkillers

Scientists studying one of nature's simplest organisms have helped to unravel the structure of a key molecule that controls pain in humans.

From The University of Manchester 12 Jul 2007

Hypnosis reduces pain perception

Hypnosis can offer significant reduction in pain awareness without any effect on non-painful aspects of the subject's perception.

20 Jun 2007

Anticonvulsant medication gabapentin effective for fibromyalgia pain

New research supported by the National Institutes of Health's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) shows that the anticonvulsant medication gabapentin, which is used for certain types of seizures, can be an effective treatment for the pain and other symptoms associated with the common, often hard-to-treat chronic pain disorder, fibromyalgia.

14 Jun 2007

Single gene is responsible for most cool temperature sensation

The discovery, reported in the May 3 issue of the journal Neuron, might one day lead to the development of drugs that induce cold sensation as an analgesic, or block it to prevent certain forms of chronic pain associated with cold sensation.

4 May 2007

Hypnotism as a potential component of care

Hypnotism has expanded its realm from magic shows to health care.

5 Apr 2007

Need for a national database of epidural complications

Researchers have called for a national database to be set up to identify major complications arising from epidural pain relief after a small number of serious problems were identified during a six-year UK study, according to the April issue of Anaesthesia.

4 Apr 2007

Effective postoperative pain control using continuous peripheral nerve block reduces days of hospitalization

Effective postoperative pain control using continuous peripheral nerve block reduced average length-of-stay by nearly a day, University of Pittsburgh School of Medicine physicians reported today during the 81st Clinical and Scientific Congress of the International Anesthesia Research Society at the Buena Vista Palace in Orlando, Fla.

3 Apr 2007

Painkiller in saliva stronger than morphine

A team of French researchers say they have found that the human body produces a natural painkiller several times more potent than morphine.

15 Nov 2006

Locally injected steroids may not do much good for chronic headache pain

Locally injected steroids apparently don't enhance treatments for acute headache or migraine pain.

18 Apr 2006

When it comes to pain, women are in fact more sensitive

For centuries, it has been generally believed women are the more sensitive gender. A new study says that, when it comes to pain, women are in fact more sensitive.

24 Oct 2005

Does clinical depression bring about chronic pain? Or does pain lead to depression?

Does clinical depression bring about chronic pain? Or does pain lead to depression? Because these two conditions frequently co-exist--30 to 54 percent of patients with major depressive disorder also suffer persistent physical pain--there has been much speculation about whether one causes the other or whether a common underlying factor provokes both. Results of studies into the precise nature of this relationship, however, have been inconsistent.

5 May 2005

MRI is both safe and accurate for diagnosing pregnant women with acute pain in the abdomen and pelvis

MRI is both safe and accurate for diagnosing pregnant women with acute pain in the abdomen and pelvis, surpassing the limits of both CT and ultrasound for this purpose, according to a new study by researchers from University of North Carolina Hospitals in Chapel Hill, NC.

3 Feb 2005

No increased cardiovascular risk seen in elderly patients taking Celebrex

The National Institutes of Health has reported in an Alzheimer's Disease prevention study that there was no increased cardiovascular risk seen in elderly patients taking Celebrex (400 mg daily) for up to three years.

21 Dec 2004

New advice on anti-inflammatory drugs called Cox-2 Inhibitors, including Celebrex

Patients who are taking Celebrex, Bextra and Arcoxia should make a non-urgent appointment with their GP to review their treatment. Patients who have established heart disease or who are at high risk of stroke will have their treatment changed.

21 Dec 2004

FDA approves Combunox tablets for the short-term treatment of acute, moderate to severe pain

Forest Laboratories have announced that Combunox (Oxycodone HCl and Ibuprofen) Tablets (CII), the first and only fixed-dose combination of the opioid oxycodone HCl (5 mg) and the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen (400 mg), was approved by the U.S. Food and Drug Administration (FDA) for the short-term management of acute, moderate to severe pain.

29 Nov 2004

MHRA advice following withdrawal of Vioxx (rofecoxib)

The Medicines and Healthcare products Regulatory Agency (MHRA) has issued advice following the withdrawal of a widely-used pain-killer and anti-inflammatory drug Vioxx (rofecoxib).

4 Oct 2004

Indicators identify shingles patients who have an increased risk of developing persistent pain

Researchers have recently confirmed a set of indicators that, alone and in combination, identify shingles patients who have an increased risk of developing persistent pain after the shingles rash heals. Results and implications of their study will be presented in the May 11 issue of Neurology, the scientific journal of the American Academy of Neurology.

10 May 2004

Morphine does not alleviate acute pain in preterm neonates

Preterm neonates undergo many painful procedures as part of their standard care in the Neonatal Intensive Care Unit (NICU). Preterm babies are able to experience pain and indeed are highly sensitive to it.

2 May 2004