Acute Pancreatitis News and Research

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Acute pancreatitis is a sudden inflammation of the pancreas. Depending on its severity, it can have severe complications and high mortality despite treatment. While mild cases are often successfully treated with conservative measures, such as NPO (nil by mouth or NBM) and IV fluid rehydration, severe cases may require admission to the ICU or even surgery (often requiring more than one intervention) to deal with complications of the disease process.

Early detection of PGAP may reduce mortality rate

Gastrectomy is commonly performed for both benign and malignant lesions. Although the incidence of post-gastrectomy acute pancreatitis (PGAP) is low compared to other well-recognized post-operative complications, it has been reported to be associated with a high mortality rate.

19 Oct 2009

Safety profiles of JANUVIA and JANUMET drugs established through clinical development program

Merck has thoroughly reviewed the safety data for sitagliptin, and sitagliptin was not associated with an increase in the incidence of pancreatitis in preclinical studies or in clinical trials of up to two years in duration with more than 6,000 patients.

28 Sep 2009

Amsterdam Molecular Therapeutics reports 2009 half year financials

Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, today reported its results for the first half year of 2009.

13 Aug 2009

Study redefines alcohol and smoking’s role in pancreatitis

Although alcohol consumption is known to be associated with chronic pancreatitis, new evidence indicates that a threshold of five or more drinks per day is required to significantly raise risk; however, most patients with chronic pancreatitis do not drink this amount, according to a report in the June 8 issue of Archives of Internal Medicine. In addition, smoking is an independent, dose-dependent risk factor.

9 Jun 2009

Amsterdam Molecular Therapeutics commences preregistration trial for Glybera

Amsterdam Molecular Therapeutics announced today the treatment of the first patient in a preregistration clinical trial with Glybera. This gene therapy product targets lipoprotein lipase deficiency (LPLD), a seriously debilitating and potentially lethal disease.

7 May 2009

Researchers hunt for new drugs for Leishmaniasis

Hundreds of millions of people, mainly in developing countries, are disabled by infectious diseases, according to the World Health Organization.

16 Dec 2008

Pancreatitis link to Gardasil to be investigated by the TGA

Some Australian doctors are suggesting that a review of the cervical cancer vaccine Gardasil is called for after three patients contracted pancreatitis after having the vaccination.

18 Aug 2008

Probiotics help keep elite athletes fit and well

According to the latest Australian research the immune system of long-distance runners was enhanced by probiotics - dietary supplements containing potentially beneficial bacteria or yeasts.

13 Feb 2008

Early surgical treatment contributes to better outcomes in gallstone pancreatitis cases

Although delaying surgical treatment remains the standard of care for patients with severe gallstone pancreatitis, a new study published in the December issue of the Journal of the American College of Surgeons shows that, contrary to widespread belief, early cholecystectomy -- or surgical removal of the gallbladder -- significantly reduces hospital stays in patients with mild to moderate gallstone pancreatitis with no increase in complications or mortality.

20 Dec 2007

New understanding on alcohol's role in developing alcoholic chronic pancreatitis

Chronic, excessive alcohol consumption is a major risk factor for developing chronic pancreatitis (pancreatic inflammation).

18 Dec 2007

Large dose dexamethasone plays important roles in severe acute pancreatitis

Severe acute pancreatitis (SAP) is a fatal systemic disease featuring acute onset, serious conditions, high incidence of complications and 20 - 30% mortality, mainly due to multiple organ failure at its early stage.

5 Nov 2007

Is it pancreatitis in acute abdominal pain in acute viral hepatitis?

Hepatitis viruses have a strong tropism for hepatocytes; viral antigen also has been detected in pancreas and gallbladder.

1 Nov 2007

Acute pancreatitis and cholangitis

Percutaneous endoscopic gastrostomy (PEG) is generally considered to be safe with a low rate of serious complications.

25 Oct 2007

Baicalin shows promise for severe acute pancreatitis

¡°Qingyitang¡±, a representative prescription of Traditional Chinese Medicine for SAP was widely used in the orients countries.

18 Oct 2007

Short-term hemofiltration is cost-effective for severe acute pancreatitis

Early nasogastric enteral nutrition is a breakthrough in the management of severe acute pancreatitis.

15 Oct 2007

New detection techniques for pancreatic cancer

Using novel light-scattering techniques, researchers have found the first evidence that early stage pancreatic cancer causes subtle changes in part of the small intestine.

3 Aug 2007

Screening method for pancreatic cancer in asymptomatic patients

EVANSTON, Ill. --- Optical technology developed by a Northwestern University biomedical engineer shown to be effective in the early detection of colon cancer now appears promising for detecting pancreatic cancer, the fourth most common cause of cancer deaths in the United States.

2 Aug 2007

Gene therapy offers promising approach to tackle pancreatic cancer

A molecularly engineered therapy selectively embeds a gene in pancreatic cancer that shrinks or eradicates tumors, inhibits metastasis, and prolongs survival with virtually no toxicity, researchers from The University of Texas M. D. Anderson Cancer Center report in the July 9 edition of Cancer Cell.

10 Jul 2007

Alarming deaths of Tamiflu patients - FDA to investigate

The U.S. Food and Drug Administration are investigating the deaths of 12 children in Japan who took Roche's flu-fighting drug Tamiflu.

20 Nov 2005

UK Rates of acute pancreatitis have doubled over the past 30 years

Rates of acute pancreatitis (inflammation of the pancreas) have doubled over the past 30 years, particularly among younger age groups, finds a study in this week's BMJ.

17 Jun 2004