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Adjuvant Therapy is treatment given after the primary treatment to increase the chances of a cure. Adjuvant therapy may include chemotherapy, radiation therapy, hormone therapy, or biological therapy.

FISH technology accurate in measuring the HER-2 receptor in human breast tumors

20. November 2009 11:24
The debate on how to select patients who will respond best to costly drug treatments for aggressive breast cancer now favors fluorescence in situ hybridization (FISH) to measure the HER-2 receptor found in human breast tumors, according to a leading pathologist presenting at the Association for Molecular Pathology annual meeting. [More]

Comprehensive report on CRC market

12. November 2009 01:41
Research and Markets (http://www.researchandmarkets.com/research/476754/pipeline_insight) has announced the addition of the "Pipeline Insight: Colorectal Cancer - Growing Trend Towards Personalized Medicine" report to their offering. [More]

Capecitabine in chemotherapy regimen reduces early breast cancer recurrence

11. November 2009 03:43
An analysis conducted by the Finnish Breast Cancer Group and published in The Lancet Oncology shows women at intermediate to high-risk of early breast cancer recurrence who received capecitabine as part of their chemotherapy regimen had a 34% reduction in the risk of the disease returning or death, compared with those taking the chemotherapy combination regimen without capecitabine. [More]

Webinar: Latest updates on percutaneous and transcatheter treatment of liver, kidney and lung tumor ablation

7. November 2009 02:00
Registration is now open for the Society of Interventional Radiology's "Image-guided Interventional Oncology (IO) Therapies" Webinar, which will provide the latest updates on percutaneous and transcatheter treatment of liver tumors, kidney tumor ablation and lung tumor ablation. [More]

Study reveals high risk of recurrence for early-stage breast cancer patients with HER2 positive tumors

3. November 2009 03:54
Early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller are at significant risk of recurrence of their disease, compared to those with early-stage disease who do not express the aggressive protein, according to a study led by researchers at The University of Texas M. D. Anderson Cancer Center. [More]

Studies demonstrate that investigational cancer vaccines show encouraging immune response rates

30. October 2009 06:00
Results of two phase 1 studies demonstrate that the novel, investigational cancer vaccines MKC1106-MT and MKC1106-PP are well-tolerated and show encouraging immune response rates and objective tumor response in advanced melanoma, prostate cancer and other solid malignancies, setting the stage for phase 2 studies. [More]

NCCN Guidelines for breast cancer does not recommend prophylactic mastectomy in women

29. October 2009 04:54
Despite a recent study finding that an increasing number of women who had cancer in one breast are opting to have the other breast removed, the National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Oncology(TM) for Breast Cancer discourages prophylactic mastectomy in women except for those considered high risk. [More]

Results from Phase I dose-escalation study of AT-101 announced

26. October 2009 08:37
Ascenta Therapeutics announced today that encouraging results from a Phase I dose-escalation study of two combination therapy regimens containing AT-101, an oral, pan-Bcl-2 inhibitor, in patients with the most malignant type of brain tumor, were described in an oral presentation at the 2009 Joint Meeting of the Society for NeuroOncology (SNO) and AANS/CNS Section on Tumors in New Orleans, Louisiana (Concurrent Session VI: Radiation Oncology, October 23, 2009; Abstract # 449). [More]

Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals start Phase 3 trial to evaluate Nexavar tablets

23. October 2009 03:42
Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. today announced the companies have begun enrolling patients in an international Phase 3 trial to evaluate Nexavar® (sorafenib) tablets for the treatment of patients with radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer. [More]

Research to develop small-molecule drug that blocks excess iron absorption

25. September 2009 06:53
Excess iron in the body, if left unchecked, can form toxic deposits in major organs leading to serious conditions including heart failure, diabetes, liver cirrhosis, arthritis, and even infertility. Iron overload can be a consequence of a genetically mutated gene known as hereditary hemochromatosis, or a consequence of red blood cell transfusions, required as life saving treatments, for patients with diseases such as thalassemia. [More]

Phase 2 trial results of Bayer's Nexavar in combination with capecitabine announced

23. September 2009 07:13
Bayer HealthCare Pharmaceuticals and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced the full results from their first collaborative group-sponsored randomized, double-blind, placebo-controlled Phase 2 trial showing that Nexavar(R) (sorafenib) tablets in combination with the oral chemotherapeutic agent, capecitabine, significantly extended progression-free survival in patients with advanced breast cancer. [More]

Report on the 10th Annual Lynn Sage Breast Cancer Symposium

23. September 2009 01:42
Research and Markets (http://www.researchandmarkets.com/research/e9ea84/lynn_sage_breast_c) has announced the addition of the "Lynn Sage Breast Cancer Symposium" training to their offering. [More]

Pfizer Oncology to present early-stage research of investigational agents for cancer treatment

19. September 2009 01:32
Pfizer Oncology will present data from across its portfolio, including results from long-term follow-up of Aromasin® (exemestane tablets) in a study of early breast cancer, updated study results from a Phase 3 study of Sutent® (sunitinib malate) in pancreatic neuroendocrine tumors (NET), and early-stage research of investigational agents PF-02341066 and figitumumab (CP-751,871) in patients with non-small cell lung cancer (NSCLC). [More]

Bayer HealthCare to present its clinical trial data at a joint Multidisciplinary Congress

17. September 2009 04:33
Bayer HealthCare today announced that data from more than 30 clinical trials evaluating three products in the company's oncology portfolio - Nexavar(R) (sorafenib) tablets, regorafenib (BAY 73-4506) and Alpharadin(TM) - will be presented at the joint 15th European CanCer Organisation (ECCO) and 34th European Society for Medical Oncology (ESMO) Multidisciplinary Congress, September 20-24, 2009 in Berlin, Germany. [More]

Oncotype DX multigene expression test for breast cancer patients

4. September 2009 01:58
In an effort to provide breast cancer patients with prompt, critical information about treatment options for use at their first visit with the medical oncologist, a number of leading U.S. surgeons request Genomic Health's Oncotype DX molecular test at the time of surgery or biopsy. [More]
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