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Discovery of compound that reduces hallmark lesions of Alzheimer's disease in mice

Researchers at UC Irvine have found that a new compound not only relieves the cognitive symptoms of Alzheimer's disease, but also reduces the two types of brain lesions that are hallmarks of this devastating disease, thereby blocking its progression.

7 Mar 2006

Bristol-Myers Squibb and Otsuka Pharmaceutical announce availability of 2 mg Abilify (aripiprazole) tablet

Bristol-Myers Squibb Company and Otsuka Pharmaceutical Co., Ltd. today announced two newly available options of Abilify (aripiprazole) -- a 2 mg tablet strength and a nonrefrigerated oral solution (1 mg/mL).

7 Feb 2006

Women with endometriosis undergoing IVF benefit from treatment with GnRH agonists

The live birth rate per woman was significantly higher in women with endometriosis who received gonadotrophin releasing hormone (GnRH) agonist for three to six months before commencing in vitro fertilisation (IVF), compared to control groups.

25 Jan 2006

Fish oil shown to reduce airway inflammation caused by exercise-induced asthma

People suffering from exercise-induced asthma were able to reduce their symptoms below the threshold used to diagnose the disease by eating a diet supplemented with fish oil, according to new research findings from Indiana University reported in the January issue of the journal Chest.

10 Jan 2006

Warnings on popular asthma drug could damage drug giant

The U.S. Food and Drug Administration (FDA) is recommending new restrictions on the asthma drug Advair.

21 Nov 2005

Allergists help manage asthma better

Compared to patients receiving care from primary care physicians, asthma patients who are under the care of an allergist report fewer asthma control problems and less sever asthma symptoms, according to new research in the December 2005 Journal of Allergy & Clinical Immunology (JACI).

20 Nov 2005

Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis

"Recurrent wheeze and breathlessness are common in people with cystic fibrosis, and bronchodilators are commonly prescribed," according to lead author Clare Halfhide, M.D., of the Royal Liverpool Children's Hospital in England. "Despite their wide-scale and often long-term use, there is limited objective evidence about their efficacy in cystic fibrosis."

25 Oct 2005

Comprehensive home-based environmental intervention results in decreased asthma symptoms

Through efforts to limit exposure to environmental irritants, health workers and municipalities can cut illness generally among inner-city children with asthma and also the number of clinic visits for those young patients by at least 19 percent, a new study concludes. The cost can be as low as $1,469 per affected family.

25 Oct 2005

LABA medications, asthma and inhaled steroids

A combination of airway-opening drugs and inhaled inflammation-reducing steroids works better at preventing severe asthma attacks than a normal dose of steroids alone, according to a new review of recent studies.

18 Oct 2005

Governments considering reclassifying some drugs from prescription to over-the-counter status

Governments in several countries with public Pharmacare and in a few provinces in Canada are considering reclassifying some drugs from prescription to over-the-counter status. In a Canadian Medical Association Journal essay, Lynd and colleagues comment on the economic effects of such changes.

27 Sep 2005

Parkinson's dark period can be minimized or alleviated with the right kind of care

Some people call it "the dark time," the period between when a person is diagnosed with Parkinson's disease and when treatment with medication begins.

26 Sep 2005

First trial of pramipexole for the treatment of fibromyalgia

The mechanism of fibromyalgia, a chronic illness characterized by muscle pain, fatigue, and sleep disturbances, is unknown and medications used to treat it (such as antidepressants, antiepileptics, muscle relaxants, antiinflammatories, sedative hypnotics, pain relievers and nutriceuticals) have had limited success.

28 Jul 2005

FDA panel says asthma drugs should stay on market but must carry warnings

The U.S. Food and Drug Administration (FDA) advisory panel has declared that three asthma drugs are safe enough to stay on the market, after concerns that in rare cases they raise the risk of severe asthma.

14 Jul 2005

Gambling and sex addiction caused by Parkinson's drug

According to a doctor at a clinic in the U.S., a certain category of drug, which is often prescribed for Parkinson's disease, can cause some patients to become compulsive gamblers or addicted to sex.

11 Jul 2005

Dopamine agonist therapy for Parkinson's disease may lead to problem gambling

Eleven patients with Parkinson's disease (PD) developed pathological gambling behavior following dopamine agonist therapy, a drug therapy to control movement problems caused by Parkinson's disease, according to a study posted online which will appear in the September print issue of Archives of Neurology.

11 Jul 2005

Chronic insomnia medicines have not yet been rigorously evaluated for long-term use

Many of the medications widely used to manage chronic insomnia have not yet been rigorously evaluated for long-term use, according to an independent scientific panel convened this week by the National Institutes of Health.

16 Jun 2005

Link between the protective effect of ischemic preconditioning in skeletal muscles and the substance that triggers hibernation

A phenomenon known as ischemic preconditioning (IP), in which blood flow to muscle is reduced and then restored, has previously been shown to increase muscle function, especially in the heart.

6 Jun 2005

Hybridon collaborates to develop immune modulatory (IMO) compounds for asthma and allergy

Hybridon today announced it had entered into research collaboration and license agreements with Novartis for the discovery, optimization, development and commercialization of Toll-like receptor 9 (TLR9) drug candidates targeting asthma and allergy based on Hybridon's proprietary immune modulatory oligonucleotide (IMO) technology platform.

1 Jun 2005

GlaxoSmithKline to acquire Corixa Corporation

GlaxoSmithKline has announced the execution of a definitive agreement pursuant to which GSK will acquire Corixa Corporation, a developer of innovative products that regulate immunity, based in Seattle, WA (USA).

2 May 2005

Sales of asthma therapies will jump from $8.4 billion in 2003 to $13.1 billion in 2013

Decision Resources, a research and advisory firms focusing on pharmaceutical and health care issues, forecasts that sales of asthma therapies in the United States, Japan, and Western Europe will jump from $8.4 billion in 2003 to $13.1 billion in 2013.

23 Apr 2005