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The term allergy encompasses a wide range of conditions; it is not a disease in itself. In 1906 Clemens von Pirquet was the first to describe allergies as a changed or altered reaction of the immune system in response to exposure to foreign proteins. These days the term allergy – medically termed hypersensitivity, signifies an exaggerated reaction to foreign substances.
Scientists discover new way to control inflammation during worm infections and allergies

Scientists discover new way to control inflammation during worm infections and allergies

Research from The University of Manchester is bringing scientists a step closer to developing new therapies for controlling the body's response to allergies and parasitic worm infections. [More]
Dry eye strikes most often in spring

Dry eye strikes most often in spring

New ophthalmology research from the University of Miami shows that dry eye - the little understood culprit behind red, watery, gritty feeling eyes - strikes most often in spring, just as airborne allergens are surging. [More]
Enrollment begins for first major cardiovascular prevention trial for people infected with HIV

Enrollment begins for first major cardiovascular prevention trial for people infected with HIV

The first clinical trial to investigate whether treatment with a statin drug can reduce the increased cardiovascular disease risk in people infected with HIV has begun enrolling patients. Based at Massachusetts General Hospital, the six-year, $40 million REPRIEVE (Randomized Study to Prevent Vascular Events in HIV) trial will be conducted at around 100 sites in the U.S., Canada, Puerto Rico and Thailand with funding from the National Heart, Lung, and Blood Institute in collaboration with the AIDS Clinical Trials Group and support from the National Institutes of Allergy and Infectious Diseases. [More]
Children exposed to adverse childhood experience more likely to develop asthma

Children exposed to adverse childhood experience more likely to develop asthma

Robyn Wing, M.D., an emergency medicine physician at Hasbro Children's Hospital, recently led a study that found children who were exposed to an adverse childhood experience (ACE) were 28 percent more likely to develop asthma. [More]
Nuvo Research provides details of new WF10 Phase 2 clinical trial for treatment of allergic rhinitis

Nuvo Research provides details of new WF10 Phase 2 clinical trial for treatment of allergic rhinitis

Nuvo Research Inc., a specialty pharmaceutical company with a diverse portfolio of topical and immunology products, today announced additional details of its new Phase 2 clinical trial (the 2015 WF10 Trial) to assess WF10 for the treatment of allergic rhinitis. [More]
Electronic cigarettes pose particular risks to the developing brains, organs of young people

Electronic cigarettes pose particular risks to the developing brains, organs of young people

Although heavily promoted as a safer cigarette and an aid to quit smoking, electronic cigarettes and the nicotine they deliver pose particular risks to the developing brains and organs of children. Use of electronic cigarettes by school-age children has surpassed traditional cigarette smoking, and it is critical to recognize and understand the risks related to nicotine exposure, addiction, and the poor regulation of these products, as described in the comprehensive Review article "Electronic Cigarettes: Vulnerability of Youth," published in Pediatric Allergy, Immunology, and Pulmonology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. [More]
GenVec, Laboratory of Malaria Immunology and Vaccinology sign research collaboration agreement

GenVec, Laboratory of Malaria Immunology and Vaccinology sign research collaboration agreement

GenVec, Inc. today announced that it has signed a research collaboration agreement with the Laboratory of Malaria Immunology and Vaccinology of the National Institute of Allergy and Infectious Diseases, National Institutes of Health. [More]
Cincinnati Children's pediatric allergist offers tips to combat allergies

Cincinnati Children's pediatric allergist offers tips to combat allergies

One of the problems that parents may have during the springtime is deciphering whether their children's sneezing is due to a cold or allergies. [More]
Study opens door to new treatment for hard-to-treat asthmatic children

Study opens door to new treatment for hard-to-treat asthmatic children

Researchers have identified a biological basis for asthmatic children who do not respond well to corticosteroid treatment – currently the most effective treatment for chronic asthma and acute asthma attack. [More]
NIH-supported clinical trial to test statin use in patients with HIV-related cardiovascular disease

NIH-supported clinical trial to test statin use in patients with HIV-related cardiovascular disease

Researchers have begun enrolling participants in a multicenter international clinical trial to test whether statin administration can reduce the risk for major adverse cardiovascular events, such as heart attacks, strokes, and heart disease, in people with HIV infection. The trial is supported by the National Institutes of Health's National Heart, Lung, and Blood Institute and National Institute of Allergy and Infectious Diseases. [More]
NIAID funds nine research projects to advance rapid diagnostics tests for drug-resistant bacteria

NIAID funds nine research projects to advance rapid diagnostics tests for drug-resistant bacteria

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded more than $11 million in first-year funding for nine research projects supporting enhanced diagnostics to rapidly detect antimicrobial-resistant bacteria. [More]
Protein-degrading enzyme can trigger strong allergic reactions through skin

Protein-degrading enzyme can trigger strong allergic reactions through skin

Papain is an important industrial protein-degrading enzyme that is used, for example, in the food and cosmetic industries. [More]
Researchers use new gene editing tool to cut HIV DNA

Researchers use new gene editing tool to cut HIV DNA

The virus that causes AIDS is an efficient and crafty retrovirus. Once HIV inserts its DNA into the genome of its host cells, it has a long incubation period, and can remain dormant and hidden for years. [More]
Enhanced biodiversity of worms, germs associated with better immune function, overall health

Enhanced biodiversity of worms, germs associated with better immune function, overall health

A growing body of evidence in the medical community holds that greater diversity of bacteria and even worms in the digestive tract offers protection against a variety of allergic and autoimmune problems. [More]
Phase 1 clinical trial: Anti-HIV antibody significantly decreases HIV levels

Phase 1 clinical trial: Anti-HIV antibody significantly decreases HIV levels

A single infusion of an experimental anti-HIV antibody called 3BNC117 resulted in significantly decreased HIV levels that persisted for as long as 28 days in HIV-infected individuals, according to Phase 1 clinical trial findings published online today in Nature. [More]
New simeprevir clinical data to be presented at EASL's International Liver Congress 2015

New simeprevir clinical data to be presented at EASL's International Liver Congress 2015

Janssen Sciences Ireland UC, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, today announced that clinical data for simeprevir, its NS3/4A protease inhibitor for the treatment of hepatitis C virus (HCV) infection, will be presented at The International Liver Congress 2015 of the European Association for the Study of the Liver taking place in Vienna from April 22-26. [More]
Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

Researchers from the School of Medicine at The University of Texas Health Science Center at San Antonio today revealed the molecular structure of the cytotoxin from Mycoplasma pneumoniae, a widespread, highly contagious bacterium that infects the lungs. [More]
MGH investigators identify inflammatory molecule that plays key role in lupus

MGH investigators identify inflammatory molecule that plays key role in lupus

Massachusetts General Hospital (MGH) investigators have identified an inflammatory molecule that appears to play an essential role in the autoimmune disorder systemic lupus erythematosus, commonly known as lupus. [More]
Scientists identify rhinovirus C receptor associated with severe asthma attacks

Scientists identify rhinovirus C receptor associated with severe asthma attacks

Scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have identified a cellular receptor for rhinovirus C, a cold-causing virus that is strongly associated with severe asthma attacks. [More]
Breast milk purchased online has significant amounts of cow's milk added, study finds

Breast milk purchased online has significant amounts of cow's milk added, study finds

A study published today on the safety of human breast milk bought over the Internet found that 10 percent of samples contained added cow's milk. The discovery that purchased samples of human milk may be purposely "topped off" with cow's milk or infant formula confirms a danger for the large number of babies receiving the purchased milk due to medical conditions. [More]
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