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Study finds age-dependent differences in expression of allergy to dust mites

Study finds age-dependent differences in expression of allergy to dust mites

In adults with a house dust mite allergy, a cascade of inflammatory signals on the surface of the airways leads to airway remodeling. [More]
Researchers develop new method to culture norovirus in intestinal cells

Researchers develop new method to culture norovirus in intestinal cells

Researchers have succeeded in culturing norovirus in human intestinal cells, a breakthrough that could help scientists develop novel therapeutics and vaccines against the debilitating effects of the virus. [More]
Children with existing food allergy at increased risk of developing asthma and rhinitis

Children with existing food allergy at increased risk of developing asthma and rhinitis

Children with a history of food allergy have a high risk of developing asthma and allergic rhinitis during childhood as well. [More]
Cedars-Sinai study identifies metabolic enzyme that alerts the body to invading bacteria

Cedars-Sinai study identifies metabolic enzyme that alerts the body to invading bacteria

Biomedical investigators at Cedars-Sinai have identified an enzyme found in all human cells that alerts the body to invading bacteria and jump-starts the immune system. [More]
Climate change could contribute to increase in hay fever from ragweed pollen for millions

Climate change could contribute to increase in hay fever from ragweed pollen for millions

Climate change could cause new hay fever misery for millions of people across Europe - according to a new report from the FP7-EU project Atopica. [More]
High exposure to unconventional natural gas wells linked to migraine headaches, sinus and fatigue

High exposure to unconventional natural gas wells linked to migraine headaches, sinus and fatigue

New research suggests that Pennsylvania residents with the highest exposure to active natural gas wells operated by the hydraulic fracturing ("fracking") industry are nearly twice as likely to suffer from a combination of migraine headaches, chronic nasal and sinus symptoms and severe fatigue. [More]
Cloned Zika virus could be used for development of attenuated vaccine

Cloned Zika virus could be used for development of attenuated vaccine

Stopping the explosive spread of Zika virus - which can lead to birth defects in babies born to infected mothers - depends on genetic insights gleaned through new tools and models. [More]
NIH researchers discover rare, lethal inflammatory disease that affects young children

NIH researchers discover rare, lethal inflammatory disease that affects young children

National Institutes of Health researchers have discovered a rare and sometimes lethal inflammatory disease - otulipenia - that primarily affects young children. They have also identified anti-inflammatory treatments that ease some of the patients' symptoms: fever, skin rashes, diarrhea, joint pain and overall failure to grow or thrive. [More]
New book from Cold Spring Harbor examines major antibiotics and mechanisms of resistance

New book from Cold Spring Harbor examines major antibiotics and mechanisms of resistance

One of the greatest medical accomplishments of the past century was the introduction of antibiotics into the clinic. [More]
Penicillin allergy testing: an interview with Dr. Eric Macy

Penicillin allergy testing: an interview with Dr. Eric Macy

Penicillin was one of the first antibiotics developed and has saved millions of lives. First used in the early 1940s, penicillin is still one of the most widely used and least toxic family of antibiotics. [More]
NIH funds collaborative project to develop better vaccine adjuvants for many diseases

NIH funds collaborative project to develop better vaccine adjuvants for many diseases

Dr. Qizhi Cathy Yao, professor of surgery, molecular virology and microbiology, and pathology & immunology at Baylor College of Medicine, has been awarded a National Institutes of Health grant to fund a collaborative project with Molecular Express, Inc. [More]
Hygiene hypothesis: a misleading misnomer? An interview with Professor Sally Bloomfield

Hygiene hypothesis: a misleading misnomer? An interview with Professor Sally Bloomfield

Professor Strachan first proposed the hygiene hypothesis back in 1989. Reviewing the evidence, he suggested that one of the causes of the recent rapid rise in allergic diseases in children was lack of exposure to childhood infections [More]
Study finds oral immunotherapy safe, effective at suppressing peanut allergy in preschool children

Study finds oral immunotherapy safe, effective at suppressing peanut allergy in preschool children

Nearly 80 percent of peanut-allergic preschool children successfully incorporated peanut-containing foods into their diets after receiving peanut oral immunotherapy (OIT), a clinical trial has found. [More]
Scientists improve potential weapon to fight against autoimmune disorders

Scientists improve potential weapon to fight against autoimmune disorders

With a trick of engineering, scientists at the Gladstone Institutes improved a potential weapon against inflammation and autoimmune disorders. Their work could one day benefit patients who suffer from inflammatory bowel disease or organ transplant rejection. [More]
TSRI scientists zoom in to view how experimental therapy ZMapp targets Ebola virus

TSRI scientists zoom in to view how experimental therapy ZMapp targets Ebola virus

Scientists at The Scripps Research Institute now have a high-resolution view of exactly how the experimental therapy ZMapp targets Ebola virus. [More]
Seasonal allergies may alter the brain, study shows

Seasonal allergies may alter the brain, study shows

Hay fever may do more than give you a stuffy nose and itchy eyes, seasonal allergies may change the brain, says a study published in the open-access journal Frontiers in Cellular Neuroscience. [More]
UM SOM selected as study site for human safety trial of new Zika vaccine

UM SOM selected as study site for human safety trial of new Zika vaccine

As world leaders increasingly recognize the Zika virus as an international public health threat, the Center for Vaccine Development at the University of Maryland School of Medicine's Institute for Global Health has been chosen as one of three study sites in a human safety trial of a new Zika vaccine. [More]
Genome-wide study sheds light on evolution of pollen allergens

Genome-wide study sheds light on evolution of pollen allergens

A joint University of Adelaide-Shanghai Jiao Tong University study has provided the first broad picture of the evolution and possible functions in the plant of pollen allergens. [More]
Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK's most common cause of blinding conjunctivitis. [More]
Amish farm environment protects children from asthma by shaping immune system

Amish farm environment protects children from asthma by shaping immune system

By probing the differences between two farming communities—the Amish of Indiana and the Hutterites of South Dakota—an interdisciplinary team of researchers found that specific aspects of the Amish environment are associated with changes to immune cells that appear to protect children from developing asthma. [More]
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