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Positive results from Transave's Phase II ARIKACE clinical trials

20. October 2009 00:01
Transave Inc., today reported additional positive clinical trial results on its lead investigational drug, ARIKACE(TM) (liposomal amikacin for inhalation), an antibiotic that aims to treat chronic lung infections. [More]

Posted in: Drug Trial News | Medical Condition News

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Positive results from Transave's Phase II clinical trial of ARIKACE in non-CF bronchiectasis patients

14. September 2009 09:31
Transave, Inc., today reported positive results from a Phase II clinical trial in non-cystic fibrosis (CF) bronchiectasis patients for its lead investigational drug, ARIKACE(TM) (liposomal amikacin for inhalation). The Phase II data indicated that ARIKACE, delivered once daily for 28 consecutive days, demonstrated superior clinical benefit compared to placebo as measured by patient and physician reported outcomes and reduction in Pseudomonas aeruginosa density. [More]

Posted in: Drug Trial News | Medical Condition News

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Clinical data on CXA-101 to be presented at ICAAC

14. September 2009 05:44
Calixa Therapeutics Inc., a clinical-stage biopharmaceutical company focused on the development and commercialization of novel antibiotics for the treatment of antibiotic-resistant infections, will present pre-clinical and clinical data in 20 posters at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) that is being held in San Francisco on September 12 to 15, 2009. [More]

Posted in: Drug Trial News

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Lancet Infectious Diseases examines spread of XDR-TB

24. June 2009 23:59
The journal Lancet Infectious Diseases examines the worldwide spread of extensively drug-resistant tuberculosis (XDR-TB). Currently, about 500,000 of the 9 million new cases of TB that are identified each year are strains of XDR-TB. "Drug resistance is largely man-made - it is vitally important to review antibiotic treatment strategies and to ensure the Stop TB Strategy is fully applied to prevent further selection of drug-resistant mutants," Leonard Amaral of Universidade Nova de Lisboa said. [More]

XDR-TB declining in the U.S.

11. November 2008 23:06
A new report suggests that the number of cases of extensively drug-resistant tuberculosis (XDR-TB) in the U.S. has declined in the past fifteen years, but new cases continue to be reported, according to the study published in the November 12 issue of JAMA. [More]

Increasing transmission of drug resistant tuberculosis in the UK

1. May 2008 23:09
A changing population structure and ongoing migration have increased cases of drug resistant tuberculosis, according to a study published on bmj.com today. [More]

Posted in: Disease/Infection News

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WHO ready to tackle drug resistant TB

25. June 2007 07:17
According to the World Health Organization (WHO) some forms of tuberculosis (TB) are a threat to the security and stability of global health. [More]

New plan to contain extensively drug-resistant TB (XDR-TB)

22. June 2007 17:07
Hundreds of thousands of cases of drug-resistant tuberculosis (TB) can be prevented and as many as 134 000 lives saved through the implementation of a two-year response plan, published/launched today by the World Health Organization (WHO) and the Stop TB Partnership. [More]

Study shows how antibiotic gentamicin affects cystic fibrosis patients with a stop mutation

30. March 2007 05:45
Genetics tests could help provide cystic fibrosis (CF) patients with targeted treatment in future, pilot study authors suggest. [More]

Posted in: Drug Trial News

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Measures to combat XDR-TB worldwide

17. October 2006 15:11
Health experts have confirmed that the emergence of extensively drug-resistant tuberculosis (XDR-TB) poses a serious threat to public health, particularly when associated with HIV. [More]

Third Melbourne hospital infected by Serratia bacteria

22. April 2004 19:45
A spokeswoman for The Royal Women's Hospital says three babies so far have been isolated after they were found to be carrying the serratia bacteria. [More]

Posted in: Disease/Infection News

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