Amyotrophic Lateral Sclerosis News and Research

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Ohio State University Wexner Medical Center administers first targeted gene therapy for ALS

The Ohio State University Wexner Medical Center is one of the first nationwide to administer a targeted gene therapy for patients with a specific form of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.

8 Sep 2023

Speech Accessibility Project needs more participants with Parkinson's

The Speech Accessibility Project is almost halfway through its first phase of gathering voice recordings from people with Parkinson's.

24 Aug 2023

Engineered adeno-associated virus vector yields high transduction of the brain vasculature

Researchers have developed an engineered adeno-associated virus (AAV) vector that yields high transduction of brain vascular pericytes and smooth muscle cells.

24 Aug 2023

Zebrafish model could help unlock Parkinson's disease mechanisms

Nearly one million people in the United States are living with Parkinson's disease, making it the second-most common neurodegenerative disease after Alzheimer's.

21 Aug 2023

A new Medicare proposal would cover training for family caregivers

Even with extensive caregiving experience, Patti LaFleur was unprepared for the crisis that hit in April 2021, when her mother, Linda LaTurner, fell out of a chair and broke her hip.

18 Aug 2023

Machine learning in neurodegenerative disease research: a growing trend

Scientists explore the utility of machine learning methods in the field of neurodegenerative disease diagnosis, prognosis, and treatment effect prediction.

4 Aug 2023

Study finds α5 integrin as a potential therapeutic target in amyotrophic lateral sclerosis

Researchers examined the therapeutic effects of targeting integrins for treating Amyotrophic lateral sclerosis (ALS).

3 Aug 2023

Research reveals surprising genetic overlap between neurological and psychiatric disorders

Researchers compared the shared genetic risk and biological foundations of neurological and mental illnesses.

1 Aug 2023

Monoclonal antibody shows promise in slowing progression of ALS

New research reveals a type of monoclonal antibody already tested in certain forms of cancer may be a promising treatment in stopping the progression of amyotrophic lateral sclerosis, or ALS, a fatal neurodegenerative disease.

31 Jul 2023

Hundreds of proteins and mRNA molecules mislocated in ALS nerve cells

Researchers at the Francis Crick Institute and UCL have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis (ALS).

21 Jul 2023

Study highlights the potential of cell replacement therapy for Huntington's disease

New research appearing in the journal Nature Biotechnology answers important questions about the viability of treatments that seek to replace diseased and aged cells in the central nervous system with healthy ones.

17 Jul 2023

Study suggests anxiety increases the risk of subsequent cognitive progression in non-dementia elderly

Researchers investigate the effects of anxiety on cognitive degeneration in non-dementia elderly.

14 Jul 2023

British neuroscientist wins Hartwig Piepenbrock-DZNE Prize for contributions to dementia research

This year's "Hartwig Piepenbrock-DZNE Prize", endowed with 60,000 euros, goes to the British neuroscientist Alison Goate, DPhil. The award recognizes her outstanding contributions to research into Alzheimer's disease and frontotemporal dementia.

13 Jul 2023

Study shows potential for treating ALS with two existing drugs

New research suggests that targeting autoimmune inflammation associated with amyotrophic lateral sclerosis (ALS) using two drugs, one of them already approved for multiple sclerosis, could be a promising approach for treatment.

12 Jul 2023

Eating foods high in omega-3 fatty acids may lead to slower physical decline in people with ALS

People with amyotrophic lateral sclerosis (ALS) who eat more foods high in certain omega-3 fatty acids like flaxseed oil, walnuts, canola oil and pumpkin seeds may have a slower physical decline from the disease and may have a slightly extended survival.

21 Jun 2023

ACROBiosystems Aneuro Partners with Diagnostic Biochips to Accelerate Neuroscience Drug Discovery

ACROBiosystems, through ACRO Certify and under its Aneuro brand, recently announced the launch of in vivo electrophysiology solutions for neuroscience research with Diagnostic Biochips.

From ACROBiosystems 19 Jun 2023

Detailed 3D images of the synapse offer precise geometry of interactions between individual cells

Scientists have created one of the most detailed 3D images of the synapse, the important juncture where neurons communicate with each other through an exchange of chemical signals. These nanometer scale models will help scientists better understand and study neurodegenerative diseases such as Huntington's disease and schizophrenia.

15 Jun 2023

Scientists uncover key molecular culprit in ALS: PEG10 gene implicated in pathogenesis

UBQLN2 dysfunction in ALS leads to elevated PEG10 levels, suggesting a role for retrotransposon activity in the disease. PEG10's nuclear localization alters gene expression involved in axon remodeling, implicating it as a contributing mechanism in ALS.

7 Jun 2023

Ancient, virus-like protein may contribute to ALS

More than 5,000 people are diagnosed annually with ALS (amyotrophic lateral sclerosis), a fatal, neurodegenerative disease that attacks nerve cells in the brain and spinal cord, gradually robbing people of the ability to speak, move, eat and breathe.