Amyotrophic Lateral Sclerosis News and Research

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Study uncovers a new immune culprit in Alzheimer’s disease

The reason your three-pound brain doesn't feel heavy is because it floats in a reservoir of cerebrospinal fluid (CSF), which flows in and around your brain and spinal cord.

13 Dec 2022

Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

Researchers developed a screening platform and identified molecules with anti-CoV activity.

12 Dec 2022

Collaborative work unravels hidden molecular secrets of age-related diseases

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, and the University of Copenhagen announced today the release of the first batch of results from the collaborative work directed to perform multi-omics-based analyses in the context of age-related diseases using an AI-driven target and drug discovery pipeline.

2 Dec 2022

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

In this interview, we speak to Axol Bioscience about their human iPSC-derived cells and how they have the potential to revolutionize the field of neurodegenerative disease.

From Axol Bioscience Ltd 28 Nov 2022

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Scientists at UF Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The

22 Nov 2022

Brain-machine interfaces could one day help patients who have lost speaking ability

New Caltech research is showing how devices implanted into people's brains, called brain-machine interfaces (BMIs), could one day help patients who have lost their ability to speak.

14 Nov 2022

Mechanically active adhesive prevents and supports the recovery from muscle atrophy

Muscles waste as a result of not being exercised enough, as happens quickly with a broken limb that has been immobilized in a cast, and more slowly in people reaching an advanced age.

14 Nov 2022

New studies point to a broadly applicable treatment for neurodegenerative diseases

Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.

26 Oct 2022

Exploring new therapeutic targets and biomarkers for neurodegenerative disorders

In this interview, Dr. Shebna Massey discusses neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and more. She also discusses and explores new therapeutic targets and biomarkers for these diseases.

From Sino Biological Inc. 26 Oct 2022

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

UVA Health researchers have discovered a molecule in the brain responsible for orchestrating the immune system's responses to Alzheimer's disease and multiple sclerosis (MS), potentially allowing doctors to supercharge the body's ability to fight those and other devastating neurological diseases.

17 Oct 2022

Metabolite discovery offers a potential way to address metabolic conditions

"Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health. Metabolites are the substances made and used during these metabolic processes-;or, as a new discovery out of Scripps Research and its drug development arm, Calibr, indicates, they could also be potent molecules for treating severe diseases.

13 Oct 2022

New genetically-targeted MND therapy could be a turning point for patient care

Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant physical benefits for patients after 12 months.

21 Sep 2022

RIT scientist receives $1.7 million NIH award to study how cells control the size of organelles

A Rochester Institute of Technology scientist hopes that a better understanding of how living cells maintain the size of their organelles can lead to therapies for neurodegenerative diseases.

16 Sep 2022

C-Path secures FDA Grant for new public-private partnership to benefit people with rare neurodegenerative diseases

Critical Path Institute has announced it will serve as the convener of the Critical Path for Rare Neurodegenerative Diseases, a new public-private partnership to benefit people across multiple rare neurodegenerative diseases, supported by a grant from the U.S. Food and Drug Administration.

14 Sep 2022

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis (ALS) and Fronto-Temporal Dementia (FTD).

9 Sep 2022

Gut microbes can also impact a person's neurological and emotional health, UTSW researcher says

The role of the microbiome in intestinal and systemic health has garnered close attention among researchers for many years.

9 Sep 2022

Scientists reverse the effects of lysosomal storage disorders in patient cells and mice

Scientists at the Icahn School of Medicine at Mount Sinai in New York, the National Center for Advancing Translational Sciences (NCATS), and elsewhere have reversed the effects of several life-threatening inherited neurodegenerative diseases called lysosomal storage disorders (LSDs) in patient cells and mice.

9 Sep 2022

Amyotrophic Lateral Sclerosis News and Research

Study uncovers a new immune culprit in Alzheimer’s disease

Research reveals the assembly dynamics of nucleocapsid protein condensates can be regulated by small molecules with therapeutic potential

Collaborative work unravels hidden molecular secrets of age-related diseases

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

Scientists develop RNA-targeting strategy to repair genetic cause of ALS and dementia

Brain-machine interfaces could one day help patients who have lost speaking ability

Mechanically active adhesive prevents and supports the recovery from muscle atrophy

New studies point to a broadly applicable treatment for neurodegenerative diseases

Exploring new therapeutic targets and biomarkers for neurodegenerative disorders

Newly identified brain molecule orchestrates the immune system's responses to Alzheimer's and MS

Metabolite discovery offers a potential way to address metabolic conditions

New genetically-targeted MND therapy could be a turning point for patient care

RIT scientist receives $1.7 million NIH award to study how cells control the size of organelles

C-Path secures FDA Grant for new public-private partnership to benefit people with rare neurodegenerative diseases

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

Gut microbes can also impact a person's neurological and emotional health, UTSW researcher says

Scientists reverse the effects of lysosomal storage disorders in patient cells and mice

Combined stem cell and gene therapy shows promise to treat patients with ALS

Researchers identify potential new pathway for treating a sporadic form of ALS

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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