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Non-invasive optogenetic therapy can help treat chronic pain

Non-invasive optogenetic therapy can help treat chronic pain

The potential of light as a non-invasive, highly-focused alternative to pain medication was made more apparent thanks to research conducted by scientists at the Montreal Neurological Institute and Hospital of McGill University and the McGill University Health Centre. [More]
Proliposomal ropivacaine may offer valuable new option for pain relief

Proliposomal ropivacaine may offer valuable new option for pain relief

A new "proliposomal" preparation of the local anesthetic drug ropivacaine may provide a valuable new option for pain relief in some clinical situations, with key advantages over other types of slow-release local anesthetics, suggest a pair of reports in Anesthesia & Analgesia. [More]
Anticonvulsant medication gabapentin effectively reduces common complication of PONV

Anticonvulsant medication gabapentin effectively reduces common complication of PONV

The anticonvulsant medication gabapentin—already a useful part of strategies to control pain after surgery—also effectively reduces the common complication of postoperative nausea and vomiting (PONV), reports a study in Anesthesia & Analgesia. [More]
American Pain Society releases new post-surgical pain management guideline

American Pain Society releases new post-surgical pain management guideline

The American Pain Society has released a new evidence-based clinical practice guideline, appearing in The Journal of Pain, with 32 recommendations to help clinicians achieve optimal pain management following surgery. According to numerous studies, the majority of surgical patients receive inadequate pain relief, which can heighten the risk for prolonged post-surgical pain, mood disorders and physical impairment. [More]
Iroko announces availability of VIVLODEX capsules in U.S. pharmacies for patients with OA pain

Iroko announces availability of VIVLODEX capsules in U.S. pharmacies for patients with OA pain

Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to advancing the science of analgesia, announced today that VIVLODEX (meloxicam) capsules, a nonsteroidal anti-inflammatory drug (NSAID), is now available by prescription at pharmacies across the United States. [More]
New pain management strategies key to maximizing patient outcomes after TKR procedures

New pain management strategies key to maximizing patient outcomes after TKR procedures

According to a new literature review in the February issue of the Journal of the American Academy of Orthopaedic Surgeons, a team-based care approach (consisting of the patient, family members, the orthopaedic surgeon and other medical practitioners) on total knee replacement (TKR) procedures, in conjunction with newer pain management strategies, is key to maximizing patient outcomes. [More]
Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

RNA is becoming an interesting drug target as it takes possible intervention back one step to the synthesis of a target protein, instead of trying to block or inhibit a process. [More]
Epidural analgesia has some adverse effects on newborns

Epidural analgesia has some adverse effects on newborns

Researchers from the University of Granada observed that babies born after epidural analgesia show a small decline in Apgar index values, a quick test applied to newborn babies in order to assess their general health. [More]
New perioperative guideline released for optimal management of geriatric patients

New perioperative guideline released for optimal management of geriatric patients

Responding to the needs of the country's growing older adult population, a new collaborative best practices guideline was released today for optimal care of older adults immediately before, during, and after surgical operations (a timeframe known as the "perioperative" period). [More]
Opioid prescribing guideline has immediate, sustained impact on prescribing rates

Opioid prescribing guideline has immediate, sustained impact on prescribing rates

Emergency medicine physicians at Temple University Hospital have found that an opioid prescribing guideline had an immediate and sustained impact on opioid prescribing rates for minor conditions and chronic noncancer pain in an acute care setting. [More]
EMA CHMP considers AcelRx's ARX-04 for acute pain treatment for centralized review

EMA CHMP considers AcelRx's ARX-04 for acute pain treatment for centralized review

AcelRx Pharmaceuticals, Inc., a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for the intended treatment of acute pain, reported that the Committee for Medicinal Products for Human Use (CHMP) at the European Medicines Agency (EMA) has confirmed that a Marketing Authorization Application (MAA) for ARX-04 may be submitted in the European Union (EU) under the Agency's centralized procedure. [More]

Nuvo reacquires development and marketing rights for Pliaglis

Nuvo Research Inc., a life sciences company with growing revenues and a diverse portfolio of topical products, today announced it has reacquired Pliaglis development and marketing rights for the U.S., Canada and Mexico. [More]
Soligenix reports positive results from SGX942 Phase 2 trial in patients with head and neck cancer

Soligenix reports positive results from SGX942 Phase 2 trial in patients with head and neck cancer

Soligenix, Inc., a late-stage biopharmaceutical company focused on developing and commercializing products to treat rare diseases where there is an unmet medical need, announced today positive results in its Phase 2 clinical trial, in which SGX942, a first-in-class Innate Defense Regulator (IDR), at a dose of 1.5 mg/kg, successfully reduced the median duration of severe oral mucositis by 50% in all patients and by 67% in patients receiving the most aggressive chemoradiation therapy (CRT) for treatment of their head and neck cancer. [More]
Bridion injection approved to reverse effects of neuromuscular blocking drugs used during certain types of surgery

Bridion injection approved to reverse effects of neuromuscular blocking drugs used during certain types of surgery

The U.S. Food and Drug Administration today approved Bridion (sugammadex) injection to reverse the effects of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide, which are used during certain types of surgery in adults. [More]
Egalet, Teva sign agreement to commercialize SPRIX Nasal Spray in Israel, Gaza and the West Bank

Egalet, Teva sign agreement to commercialize SPRIX Nasal Spray in Israel, Gaza and the West Bank

Egalet Corporation, a fully integrated specialty pharmaceutical company focused on developing, manufacturing and commercializing innovative treatments for pain and other conditions, today announced a collaboration agreement with Teva Pharmaceutical Industries Ltd., a leading global pharmaceutical company. [More]
Study: Spanish-speaking Hispanic women less likely to use neuraxial analgesia during labor

Study: Spanish-speaking Hispanic women less likely to use neuraxial analgesia during labor

Why do Hispanic women have reduced rates of epidural or spinal (neuraxial) analgesia during labor? Language barriers may be a key factor, according to a study in Anesthesia & Analgesia. [More]
AfBPM's second National Summit aims to improve pain management, patient safety

AfBPM's second National Summit aims to improve pain management, patient safety

The Alliance for Balanced Pain Management, a diverse collective of 24 health care advocacy groups, patient organizations, industry representatives and other stakeholders, held its second National Summit on Nov. 12 and 13, 2015, to identify continued ways to support appropriate access to integrated pain management and responsible use of prescription pain medicines with an aim to improve patient safety and reduce abuse. [More]
Cherwell selected for quality and service in environmental monitoring by Portsmouth PMU

Cherwell selected for quality and service in environmental monitoring by Portsmouth PMU

Cherwell Laboratories, specialists in cleanroom microbiology solutions for the pharmaceutical and related industries, has been assisting Portsmouth Pharmaceutical Manufacturing Unit (PMU) in their extensive environmental monitoring (EM) programme for over 20 years [More]
Sleepwalkers don't feel pain while suffering injuries

Sleepwalkers don't feel pain while suffering injuries

A new study of sleepwalkers found an intriguing paradox: Although sleepwalkers have an increased risk for headaches and migraines while awake, during sleepwalking episodes they are unlikely to feel pain even while suffering an injury. [More]
Conversational hypnosis may do better job than pills for relaxing patients before surgery

Conversational hypnosis may do better job than pills for relaxing patients before surgery

Anxious patients heading into surgery often receive medication to ease their fears, but a few calming words from their physicians might actually be more effective medicine. In fact, "conversational hypnosis" as the approach is known, may do a better job than pills for relaxing patients before anesthesia and surgery, suggests research being presented at the ANESTHESIOLOGY 2015 annual meeting. [More]
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