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Protein involved in pancreatic cancer development plays more complicated role, study finds

Protein involved in pancreatic cancer development plays more complicated role, study finds

A protein thought to fuel pancreatic cancer development plays a much more complicated role, a new study finds. [More]
Roswell Park researchers identify gene signatures that may help predict fatal prostate cancers

Roswell Park researchers identify gene signatures that may help predict fatal prostate cancers

Standard therapy for prostate cancer, the third-leading cause of cancer-related deaths in American men, is based on blocking androgens, the male sex hormones. [More]
A new strategy to fight prostate cancer

A new strategy to fight prostate cancer

A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer. [More]
Controversial hormone could fight against recurring breast cancers

Controversial hormone could fight against recurring breast cancers

An international team of researchers involving the University of Adelaide is tackling the controversy over what some scientists consider to be a "harmful" hormone, arguing that it could be a game changer in the fight against recurring breast cancers that are resistant to standard treatments. [More]
Enzyme that cleaves beta carotene may control testosterone levels

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found. [More]
Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

An international group of researchers report success in mice of a method of using positron emission tomography scans to track, in real time, an antibody targeting a hormone receptor pathway specifically involved in prostate cancer. [More]
Researchers find timing, duration of androgen exposure can influence genital defects in female mice

Researchers find timing, duration of androgen exposure can influence genital defects in female mice

University of Florida researchers have identified cells targeted by a male hormone and found that an excess of that hormone at a specific time can cause genital defects in female mice. [More]
Identifying gene defects may help develop individualised treatments for prostate cancer patients

Identifying gene defects may help develop individualised treatments for prostate cancer patients

The current method of treating prostate cancer involves identifying gene defects, which could help with the diagnosis of cancer and the development of individualised cancer treatments for patients. [More]
Men can take contraceptives to prevent pregnancy in female partners, study shows

Men can take contraceptives to prevent pregnancy in female partners, study shows

Men can take birth control shots to prevent pregnancy in their female partners, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
New oncogene may contribute to high incidence of prostate cancer among African American men

New oncogene may contribute to high incidence of prostate cancer among African American men

A team of scientists has identified MNX1 as a new oncogene - a gene than can cause cancer - that is more active in African American prostate cancer than in European American prostate cancer. [More]
Natural compound found in red wine can lower testosterone levels in women with PCOS

Natural compound found in red wine can lower testosterone levels in women with PCOS

Resveratrol—a natural compound found in red wine and grapes—can help address a hormone imbalance in women with polycystic ovary syndrome (PCOS), a leading cause of infertility in women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Common hormone therapy to treat prostate cancer may increase dementia risk in men

Common hormone therapy to treat prostate cancer may increase dementia risk in men

A common hormone therapy to treat prostate cancer may double a man's risk of dementia, regardless of his age, Penn Medicine researchers reported in a study published online today in JAMA Oncology. [More]
Study examines benefits of hormonal therapy for prostate cancer patients with prior history of heart attack

Study examines benefits of hormonal therapy for prostate cancer patients with prior history of heart attack

In a recent study, a Yale Cancer Center team determined that men who received hormonal therapy for prostate cancer had a net harm if they had a prior history of a heart attack. [More]
Researchers identify, validate three distinct molecular subtypes of prostate cancer

Researchers identify, validate three distinct molecular subtypes of prostate cancer

In the largest study of its kind to date, researchers have identified and validated three distinct molecular subtypes of prostate cancer that correlate with distant metastasis-free survival and can assist in future research to determine how patients will respond to treatment, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology. [More]
Duke researchers discover blood markers linked to drug-resistant tumor cells

Duke researchers discover blood markers linked to drug-resistant tumor cells

While searching for a non-invasive way to detect prostate cancer cells circulating in blood, Duke Cancer Institute researchers have identified some blood markers associated with tumor resistance to two common hormone therapies. [More]
Scientists find new target that may lead to future treatments for Kennedy's disease

Scientists find new target that may lead to future treatments for Kennedy's disease

If a disease affects motoneurons, cells that control voluntary muscle activity, researchers should focus their efforts on motoneurons to find potential treatments, right? Not always. [More]
T-sol can be safe and effective treatment for men with hypogonadism

T-sol can be safe and effective treatment for men with hypogonadism

For men with hypogonadism, a condition in which the body does not produce enough testosterone, low sex drive and fatigue are common symptoms. [More]
IRB Barcelona scientists rediscover utility of disordered proteins as therapeutic targets

IRB Barcelona scientists rediscover utility of disordered proteins as therapeutic targets

Prostate cancer, Alzheimer's, Parkinson's...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional structure. [More]
Novel computational analysis of prostate cancer suggests potential targets for therapy

Novel computational analysis of prostate cancer suggests potential targets for therapy

Cancer researchers have applied a comprehensive set of analytical tools to lethal cases of metastatic prostate cancer, yielding a detailed map of the complex networks of interactions among genes and proteins that enable prostate cancer cells to proliferate and evade treatment. [More]
Novel compound holds potential for next-generation prostate cancer treatment

Novel compound holds potential for next-generation prostate cancer treatment

In the search for new ways to attack recurrent prostate cancer, researchers at Duke Health report that a novel compound appears to have a unique way of blocking testosterone from fueling the tumors in mice. [More]
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