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Anemia is a decrease in normal number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency. The three main classes of anemia include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis). Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few.
New mobile health app may help manage hydroxyurea treatments in sickle cell patients

New mobile health app may help manage hydroxyurea treatments in sickle cell patients

The National Heart, Lung, and Blood Institute, part of the National Institutes of Health, has awarded a 6-year, $4.4 million grant to St. Jude Children's Research Hospital and collaborators to improve the use of prescribed medication by sickle cell patients. [More]
Study compares different strategies to prevent malaria among pregnant women in sub Saharan Africa

Study compares different strategies to prevent malaria among pregnant women in sub Saharan Africa

A novel strategy to screen pregnant women for malaria with rapid diagnostic tests and treat the test-positive women with effective antimalarials does not lower the risk of adverse pregnancy outcomes compared with treating all pregnant women with the malaria preventive sulfadoxine-pyrimethamine (SP) in sub-Saharan Africa, according to an open label randomized trial published this week in PLOS Medicine by Feiko ter Kuile, of the Liverpool School of Tropical Medicine, and colleagues. [More]
Alexion initiates new global Uncommon Strength campaign to raise awareness of rare diseases

Alexion initiates new global Uncommon Strength campaign to raise awareness of rare diseases

Alexion Pharmaceuticals, Inc. today announced the launch of Uncommon Strength, a global campaign to raise awareness of rare diseases through the celebration of the extraordinary resilience and inner strength of those impacted by these diseases. [More]
New HemaApp uses smartphone camera to screen for anemia

New HemaApp uses smartphone camera to screen for anemia

In the developing world, anemia -- a blood condition exacerbated by malnutrition or parasitic disease -- is a staggeringly common health problem that often goes undiagnosed. [More]
Research findings pave way to effective strategies for treatment of visceral leishmaniasis

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

A study shows that stimulating the production of interleukin-17A (IL-17A), one of the cytokines released by cells of the immune system, can be an effective strategy for the treatment of visceral leishmaniasis, considered one of the six most important parasitic diseases affecting humans. [More]
Penicillin allergy testing: an interview with Dr. Eric Macy

Penicillin allergy testing: an interview with Dr. Eric Macy

Penicillin was one of the first antibiotics developed and has saved millions of lives. First used in the early 1940s, penicillin is still one of the most widely used and least toxic family of antibiotics. [More]
Increased parental longevity linked to lower risk of cardiovascular conditions in offspring

Increased parental longevity linked to lower risk of cardiovascular conditions in offspring

In middle aged populations, the risks of cardiovascular conditions are progressively lower the longer a person's parents lived past 69 years old, according to a study of 186,000 participants using a voluntary database published today in the Journal of the American College of Cardiology. [More]
Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

Scientists find new way to use CRISPR gene editing to help fix sickle cell disease

An international team of scientists led by researchers at St. Jude Children's Research Hospital has found a way to use CRISPR gene editing to help fix sickle cell disease and beta-thalassemia in blood cells isolated from patients. [More]
Scientists link malfunctioning molecular pathways to specific heart abnormalities in SCA

Scientists link malfunctioning molecular pathways to specific heart abnormalities in SCA

Patients with sickle cell anemia (SCA) develop heart complications and nearly a quarter die a sudden death. Now, researchers have linked malfunctioning molecular pathways to specific heart anomalies in SCA that result from progressive fibrosis and result in sudden death. [More]
Researchers identify biophysical markers that may help improve treatments for sickle cell disease

Researchers identify biophysical markers that may help improve treatments for sickle cell disease

An interdisciplinary, international group of researchers has found new biophysical markers that could help improve the understanding of treatments for sickle cell disease, a step toward developing better methods for treating the inherited blood disorder that affects an estimated 80,000 to 100,000 Americans each year. [More]
DRG International to display Hepcidin 25 (bioactive) HS ELISA Kit at 2016 AACC Expo

DRG International to display Hepcidin 25 (bioactive) HS ELISA Kit at 2016 AACC Expo

DRG International, a leading international medical diagnostic company, will showcase the NEW DRG Hepcidin 25 (bioactive) HS (High Sensitive) ELISA Kit (EIA-5782) at the 2016 AACC in Philadelphia, Pennsylvania from August 02-04. [More]
VALIDATE D-Dimer kit from LGC Maine Standards receives US FDA approval for use on hemostasis test systems

VALIDATE D-Dimer kit from LGC Maine Standards receives US FDA approval for use on hemostasis test systems

LGC Maine Standards is pleased to announce our VALIDATE D-Dimer calibration verification / linearity test kit has received US FDA 510(k) clearance for use on Instrument Laboratory ACL TOP hemostasis test systems. [More]
PolyU researchers discover inadequate intakes of micronutrients among Hong Kong lactating women

PolyU researchers discover inadequate intakes of micronutrients among Hong Kong lactating women

While breastfeeding has become more common across the globe in recent years, lactating women may not be aware of the nutrient adequacy of their breast milk and how their daily diet affects their nutrition intakes. [More]
Scientists clarify mechanism of defective immune defense in G6PD patients

Scientists clarify mechanism of defective immune defense in G6PD patients

Favism is a common hereditary disease, affecting around 400 million people worldwide. It is caused by a lack of the enzyme glucose-6-phosphate dehydrogenase (G6PD). [More]
Male hormones can reverse biological drivers of aging, study shows

Male hormones can reverse biological drivers of aging, study shows

Telomerase, an enzyme naturally found in the human organism, is the closest of all known substances to a "cellular elixir of youth." In a recent study, Brazilian and US researchers show that sex hormones can stimulate production of this enzyme. [More]
Blood cancer is associated with considerably higher healthcare costs than other cancers

Blood cancer is associated with considerably higher healthcare costs than other cancers

Health economics studies, published today in The Lancet Haematology, report that the cost of treating blood cancers is twice that for treating other cancers. This is largely because they require more complex treatment regimens that necessitate longer hospital stays. [More]
Blood utilization practice guidelines can save millions of dollars, reduce blood wastage

Blood utilization practice guidelines can save millions of dollars, reduce blood wastage

Improving the processes of ordering, transporting, and storing blood can save millions of dollars and drastically reduce blood wastage, reported a research team from one academic medical center after implementing institutional initiatives to address blood management. [More]
Oxford scientists introduce simple nano-electrochemical process for precise determination of erythrocyte count

Oxford scientists introduce simple nano-electrochemical process for precise determination of erythrocyte count

Blood counts are routinely carried out before operations, in cases of infection, or when testing for a variety of diseases, such as anemia and leukemia. A key value in this test is the number of red blood cells (erythrocytes). [More]
Critical evaluation of EKF Diagnostics’ Quo-Test analyzer released

Critical evaluation of EKF Diagnostics’ Quo-Test analyzer released

EKF Diagnostics, the global in-vitro diagnostics company, announces the release of a significant critical evaluation of the Quo-Test analyzer carried out by the European Reference Laboratory for Gylcohemoglobin. This new evaluation represents the culmination of several years’ cooperation between EKF Diagnostics and the European Reference Laboratory to produce a world class Point-of-Care-Testing (POCT) HbA1c analyzer. [More]
European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year. [More]
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