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Inadequate monitoring places post-operative patients at risk for opioid-induced respiratory depression

Inadequate monitoring places post-operative patients at risk for opioid-induced respiratory depression

Nearly 75 percent of hospitalized patients receiving opioids for pain management are not monitored according to hospital guidelines. [More]
Pharmacist suggests education as foremost strategy to control opioid abuse

Pharmacist suggests education as foremost strategy to control opioid abuse

Technologies that make it harder for people to abuse opioids - like doctoring pills so that they produce unpleasant side effects if broken, crushed or injected -- likely will have limited effectiveness in stemming the global epidemic of opioid abuse, according to Adam Kaye, a professor of pharmacy at University of the Pacific. [More]
Closely related molecule can mimic effect of PKMzeta in mice

Closely related molecule can mimic effect of PKMzeta in mice

New research led by SUNY Downstate Medical Center shows that mice devoid of PKMzeta, a molecule previously identified by SUNY Downstate scientists as essential to memory formation and storage, recruit a closely related molecule, PKCiota/lambda, to make up for the missing PKMzeta. [More]
Study explores neurological mechanisms in action during ketamine anesthesia

Study explores neurological mechanisms in action during ketamine anesthesia

It's a topic that has long captivated doctors, scientists and the public — what exactly happens in your brain when you're oblivious on the operating table? [More]
Gene therapy could be potential treatment for neuropathic pain in cancer patients

Gene therapy could be potential treatment for neuropathic pain in cancer patients

A study providing new information about neuropathic pain afflicting some 90 percent of cancer patients who have had nerve damage caused by tumors, surgery, chemotherapy or radiation indicates gene therapy as a possible treatment. [More]
Inhibiting adrenaline receptors reduces breast cancer brain metastases

Inhibiting adrenaline receptors reduces breast cancer brain metastases

While we look to invent new medicines to treat cancer, a parallel approach to repurpose existing medicines may be highly effective. Stress, mediated by adrenaline, has been suspected to promote cancer growth and this research study shows that by blocking adrenaline receptors in breast cancers, they are less successful in spreading to and growing in the brain. [More]
UA researchers developing new treatment to delay serious consequences of venomous snakebites

UA researchers developing new treatment to delay serious consequences of venomous snakebites

Time is of the essence for treating venomous snakebites, and a product being developed by researchers at the University of Arizona College of Medicine - Tucson may extend that window for treatment. [More]
Proliposomal ropivacaine may offer valuable new option for pain relief

Proliposomal ropivacaine may offer valuable new option for pain relief

A new "proliposomal" preparation of the local anesthetic drug ropivacaine may provide a valuable new option for pain relief in some clinical situations, with key advantages over other types of slow-release local anesthetics, suggest a pair of reports in Anesthesia & Analgesia. [More]
ACB could lead to quicker, safer recovery after total knee arthroplasty

ACB could lead to quicker, safer recovery after total knee arthroplasty

Two commonly used nerve blocks during total knee arthroplasty (TKA) are the adductor canal block (ACB) and femoral nerve block (FNB). ACB appears to preserve quadriceps strength superior to FNB while maintaining adequate postoperative pain control. Improving early functional outcome could lead to a quicker and safer recovery with earlier hospital discharges. [More]
Increased use of PNBs in hip and knee arthroplasty could improve medical outcomes

Increased use of PNBs in hip and knee arthroplasty could improve medical outcomes

The use of peripheral nerve blocks (PNBs) is associated with better medical and economic outcomes in patients receiving hip and knee replacement, according to research being presented at the 41st Annual Regional Anesthesiology and Acute Pain Medicine Meeting later this month. [More]
Anticonvulsant medication gabapentin effectively reduces common complication of PONV

Anticonvulsant medication gabapentin effectively reduces common complication of PONV

The anticonvulsant medication gabapentin—already a useful part of strategies to control pain after surgery—also effectively reduces the common complication of postoperative nausea and vomiting (PONV), reports a study in Anesthesia & Analgesia. [More]
Penn study calls on physicians to avoid over-prescribing opioids for surgical patients

Penn study calls on physicians to avoid over-prescribing opioids for surgical patients

Physicians are prescribing more opioid painkillers than ever before to patients undergoing common surgeries, according to new research from the department of Anesthesiology and Critical Care at the Perelman School of Medicine at the University of Pennsylvania. [More]
Researchers identify potential drug target in skin for itchy feeling

Researchers identify potential drug target in skin for itchy feeling

No matter the trigger -- bug bites, a medication side-effect or an itchy wound -- the urge to scratch can be a real pain. Researchers at the Duke University Medical Center have identified a potential drug target in the skin for that itchy feeling. [More]
Neck pain more common in women than in men, Loyola study finds

Neck pain more common in women than in men, Loyola study finds

Women are 1.38 times more likely than men to report neck pain due to cervical degenerative disc disease, according to a study of adult patients treated at Loyola Medicine's Pain Management Center. [More]
New study sheds light on challenges in addressing post-operative bleeding in newborns

New study sheds light on challenges in addressing post-operative bleeding in newborns

A new study finds significant differences between the blood clot structure in adults and newborns, helping researchers better understand the challenges in addressing post-operative bleeding in neonatal patients. [More]
New pain management technique can reduce loss of muscle strength in ACL knee surgery patients

New pain management technique can reduce loss of muscle strength in ACL knee surgery patients

Anesthesiologists can significantly reduce loss of muscle strength in ACL knee surgery patients using a new pain management technique, a new study has found. [More]
New review suggests solutions that can help ease chronic pain in women

New review suggests solutions that can help ease chronic pain in women

Women often suffer silently when in pain, whether it's caused by pregnancy discomfort or creaky knees. Yet there are a variety of solutions that can help relieve women of chronic pain, from exercise to identifying triggers, suggests a new review of research related to women and pain by the American Society of Anesthesiologists. [More]
Study may lead to potential drug targets for tumor formation in pulmonary tuberous sclerosis complex

Study may lead to potential drug targets for tumor formation in pulmonary tuberous sclerosis complex

In a new study published in the American Association of Cancer Research's journal Cancer Research, a pair of investigators at Rutgers and Columbia universities has identified a gene that may provide a new source of potential drug targets for tumors that arise in pulmonary tuberous sclerosis complex (TSC). [More]
Aerobic exercise may prevent alcohol-related liver damage

Aerobic exercise may prevent alcohol-related liver damage

According to the Centers for Disease Control and Prevention, excessive alcohol use is responsible for more than 80,000 deaths in the United States each year. Over time, excessive drinking can lead to several chronic conditions, such as fatty liver disease and cirrhosis. [More]
New pain management strategies key to maximizing patient outcomes after TKR procedures

New pain management strategies key to maximizing patient outcomes after TKR procedures

According to a new literature review in the February issue of the Journal of the American Academy of Orthopaedic Surgeons, a team-based care approach (consisting of the patient, family members, the orthopaedic surgeon and other medical practitioners) on total knee replacement (TKR) procedures, in conjunction with newer pain management strategies, is key to maximizing patient outcomes. [More]
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