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Intra-arterial stroke treatment more effective than medical management with tPA, study finds

Intra-arterial stroke treatment more effective than medical management with tPA, study finds

Penumbra, Inc., the market leader in intra-arterial stroke treatment, announced that an independent study published online today in the New England Journal of Medicine found that intra-arterial stroke treatment, including the company's clot extraction technology, was shown to be significantly more effective than medical management with tissue plasminogen activator (tPA), which is the current standard of care. [More]
Real-time radiation-exposure feedback can help medical workers adopt safer radiation practices

Real-time radiation-exposure feedback can help medical workers adopt safer radiation practices

It's a sound that saves. A "real-time" radiation monitor that alerts by beeping in response to radiation exposure during cardiac-catheterization procedures significantly reduces the amount of exposure that medical workers receive, UT Southwestern Medical Center researchers found. [More]
OCT enhances neovascular subtype detection in AMD

OCT enhances neovascular subtype detection in AMD

Researchers recommend the inclusion of optical coherence tomography anatomic classification with fluorescein angiography grading to identify initial neovascular lesion subtypes in newly diagnosed age-related macular degeneration. [More]
Diabetic patients with mild coronary artery disease face increased risk for heart attack

Diabetic patients with mild coronary artery disease face increased risk for heart attack

According to a new long-term study, diabetic patients with even mild coronary artery disease face the same relative risk for a heart attack or other major adverse heart events as diabetics with serious single-vessel obstructive disease. [More]
A new formal protocol for emergency treatment of patients with aneurysmal SAH

A new formal protocol for emergency treatment of patients with aneurysmal SAH

Neurosurgeons and neurointerventionalists at Kyungpook National University in the Republic of Korea have developed a formal protocol for delivering emergency treatment to patients with subarachnoid hemorrhage (SAH) from ruptured aneurysms within the first few hours after bleeding occurs. [More]

FFR guided drug-eluting stenting reduces death compared to medical therapy in stable CAD patients

Fractional flow reserve (FFR)-guided drug-eluting stenting reduces death, myocardial infarction or urgent revascularisation, as compared to medical therapy in patients with stable coronary artery disease (CAD), according to the results of the FAME 2 trial presented for the first time today at ESC Congress by principal investigator Dr Bernard De Bruyne (Belgium). [More]
Measuring coronary artery blockage in heart attack patients can help avoid surgery

Measuring coronary artery blockage in heart attack patients can help avoid surgery

A method for measuring coronary artery blockage in heart attack patients can help more than one fifth of them avoid stents or surgery, according to a British study presented at the ESC Congress 2014 today. [More]
Macular ischaemia, retinal thinning linked to reduced visual function in diabetic retinopathy

Macular ischaemia, retinal thinning linked to reduced visual function in diabetic retinopathy

Macular ischemia and retinal thinning are associated with reduced visual function in patients with diabetic retinopathy, research suggests. [More]
Study of chronic users of CCS finds deficits in specific regions of brain white matter

Study of chronic users of CCS finds deficits in specific regions of brain white matter

An imaging study of chronic users of codeine-containing cough syrups (CCS) has found deficits in specific regions of brain white matter and associates these changes with increased impulsivity in CCS users. [More]
Focal choroidal excavation linked to chorioretinal diseases

Focal choroidal excavation linked to chorioretinal diseases

Results of a Japanese study show that focal choroidal excavation is present in several ocular diseases, including typical age-related macular degeneration, central serous chorioretinopathy, polypoidal choroidal vasculopathy and idiopathic choroidal neovascularization. [More]
ASAHI INTECC, Boston Scientific to develop new, differentiated FFR wire

ASAHI INTECC, Boston Scientific to develop new, differentiated FFR wire

Boston Scientific Corporation and ASAHI INTECC (Securities Code 7747, Second Section, Tokyo and Nagoya Stock Exchange) have formalized plans to develop a new, differentiated fractional flow reserve (FFR) wire. [More]
Cheaper drug could potentially improve heart attack patient outcomes and save health services millions

Cheaper drug could potentially improve heart attack patient outcomes and save health services millions

A new study published in The Lancet compares outcomes for two drugs used to prevent blood clot formation during emergency heart attack treatment. The study suggests that use of one of the drugs, heparin, could result in improved outcomes (such as a reduced rate of repeat heart attacks), compared to the other drug tested, bivalirudin, which is in widespread use in high-income countries, and is around 400 times more expensive than heparin. [More]
Cardium reports positive results from Generx Ad5FGF-4 Phase 3 study for treatment of myocardial ischemia

Cardium reports positive results from Generx Ad5FGF-4 Phase 3 study for treatment of myocardial ischemia

Taxus Cardium Pharmaceuticals Group Inc. will report today at the Biotechnology Industry Organization’s 2014 BIO International Convention on a pre-specified interim analysis from its international ASPIRE Phase 3 registration clinical study of Generx Ad5FGF-4, Cardium Therapeutics’ angiogenic gene therapy product candidate for patients with myocardial ischemia due to coronary artery disease. [More]
Non-obstructive coronary artery disease linked with 28 to 44% increased risk of major heart attack

Non-obstructive coronary artery disease linked with 28 to 44% increased risk of major heart attack

Non-obstructive coronary artery disease was associated with a 28 to 44 percent increased risk of a major adverse cardiac event such as a heart attack or death, in a new study presented at the American Heart Association's Quality of Care and Outcomes Research 2014 Scientific Sessions. [More]
Micell Technologies presents DESSOLVE I and II trial data at EuroPCR conference

Micell Technologies presents DESSOLVE I and II trial data at EuroPCR conference

Micell Technologies, Inc. today announced that long-term clinical outcomes from its DESSOLVE I and II clinical trials were presented at the EuroPCR conference in Paris, France this week. [More]
Pro-urokinase promotes angiogenesis but does not reduce neuronal apoptosis in infarcted cerebral tissue

Pro-urokinase promotes angiogenesis but does not reduce neuronal apoptosis in infarcted cerebral tissue

Among the drugs used for acute ischemic stroke, recombinant tissue plasminogen activator is widely accepted internationally. In China, urokinase has been widely used for thrombolysis after acute ischemic stroke. [More]
Genetic biomarkers of ranibizumab response remain elusive in Koreans with AMD

Genetic biomarkers of ranibizumab response remain elusive in Koreans with AMD

Researchers have failed to find a significant genotypic effect on ranibizumab treatment response in Korean patients with neovascular age-related macular degeneration. [More]
Imaging technique may help understanding of chronic CSCR

Imaging technique may help understanding of chronic CSCR

Swept-source optical coherence tomography identifies the morphological features implicated in the underlying physiopathological mechanisms of chronic central serous chorioretinopathy, researchers report. [More]
New ultrasound device could help identify arterial plaque that cause heart attack, stroke

New ultrasound device could help identify arterial plaque that cause heart attack, stroke

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a new ultrasound device that could help identify arterial plaque that is at high risk of breaking off and causing heart attack or stroke. [More]
CT angiography provides accurate assessment of arterial plaque in diabetic patients

CT angiography provides accurate assessment of arterial plaque in diabetic patients

Imaging of the coronary arteries with computed tomography (CT) angiography provides an accurate assessment of arterial plaque and could have a dramatic impact on the management of diabetic patients who face a high risk of heart attacks and other cardiovascular events, according to a new multicenter study published online in the journal Radiology. [More]