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Brain's waste removal route found in nasal lymphatics

In a groundbreaking study published in Nature, South Korean researchers led by Director KOH Gou Young of the Center for Vascular Research within the Institute for Basic Science (IBS) have uncovered a distinctive network of lymphatic vessels at the back of the nose that plays a critical role in draining cerebrospinal fluid (CSF) from the brain.

27 Jan 2024

Study confirms safety of COVID-19 vaccination during pregnancy for infant neurodevelopment

A large cohort study in "JAMA Pediatrics" found no significant differences in neurodevelopmental rates between infants exposed to COVID-19 vaccines in-utero and those who were not, affirming the safety of maternal COVID-19 vaccination.

24 Jan 2024

Study shows effectiveness of gene therapy in treating congenital deafness

A new study co-led by investigators from Mass Eye and Ear, a member of Mass General Brigham, demonstrated the effectiveness of a gene therapy towards restoring hearing function for children suffering from hereditary deafness.

24 Jan 2024

Rice scientists identify promising new immunological pathway to treat breast cancer bone metastases

Rice University researchers in the lab of chemist Han Xiao have identified a promising new immunological pathway to treat stubborn bone tumors, one of most prevalent forms of metastases in breast cancer patients.

24 Jan 2024

New study reveals effective strategies against drug resistance in hospital-acquired pneumonia treatment

A novel rabbit infection model to investigate meropenem's resistance development.

23 Jan 2024

Receptor protein found to be a key player in prostate cancer cells' drug resistance

Researchers have identified a receptor protein known as CHRM1 as a key player in prostate cancer cells' resistance to docetaxel, a commonly used chemotherapy drug to treat advanced cancer that has spread beyond the prostate.

22 Jan 2024

Does space travel impact the human reproductive system?

How space travel, space radiation, and microgravity affect human reproductive functions.

22 Jan 2024

Unveiling the cellular mechanisms of engram consolidation and memory refinement

Think of a time when you had two different but similar experiences in a short period. Maybe you attended two holiday parties in the same week or gave two presentations at work.

19 Jan 2024

Important discovery could lead to novel treatment for obesity

A team comprised primarily of Texas A&M AgriLife Research scientists has made an important discovery that could lead to a novel treatment for obesity and obesity-associated diseases or conditions.

18 Jan 2024

New structural insights pave the way for drug-resistant malaria therapies

Structural insights into a potent antimalarial drug candidate's interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute.

18 Jan 2024

Understanding antimicrobial resistance in hospital-acquired pneumonia

New research has been published that identifies positive steps towards a better understanding of antimicrobial resistance (AMR), specifically in hospital-acquired pneumonia (HAP).

18 Jan 2024

New targeted therapy eliminates cancer with zero side effects

Johannes Karges develops anti-cancer agents that work in a targeted manner, rather than adversely affecting the entire body.

18 Jan 2024

Monkey study points to HIV vulnerability for vaccine attack

Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people.

17 Jan 2024

Urea-powered nanorobots reduce bladder tumors by 90% in mice

The research, which was conducted on mice, demonstrates how these tiny nanomachines are propelled by urea present in urine and precisely target the tumour, attacking it with a radioisotope carried on their surface.

16 Jan 2024

Research team develops electrostatic materials for long-term bio-implants

Medical technology innovations achieved by integrating science and medicine have improved the quality of life for patients.

3 Jan 2024

New drug screening system helps uncover promising target for pancreatic cancer treatments

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell Medicine.

26 Dec 2023

Stem cell heart tissue model paves the way for better understanding of tachycardia

Heart rates are easier to monitor today than ever before. Thanks to smartwatches that can sense a pulse, all it takes is a quick flip of the wrist to check your heart.

20 Dec 2023

Novel molecular link between vitamin B12 and multiple sclerosis revealed in astrocytes

For decades, scientists have noted an intriguing similarity between a deficiency in vitamin B12 – an essential nutrient that supports healthy development and functioning of the central nervous system (CNS) – and multiple sclerosis (MS), a chronic disease in which the body's immune system attacks the CNS and which can produce neurodegeneration.

11 Dec 2023

Promising candidate medication for preventing and reversing fentanyl-induced overdose

Researchers assessed CSX-1004, a monoclonal antibody (mAb), for its efficacy in reversing fentanyl overdose based on its high affinity for fentanyl, positive animal model results, and safe pharmacokinetic profile, positioning it as a potential solution in the opioid crisis.

7 Dec 2023

Neuroimaging and network modeling tools shed light on Alzheimer's disease in animal models

Indiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools-;previously developed to analyze brains of patients in the clinic-;to investigate Alzheimer's disease progression in preclinical animal models.

4 Dec 2023

Animal Model News and Research

Brain's waste removal route found in nasal lymphatics

Study confirms safety of COVID-19 vaccination during pregnancy for infant neurodevelopment

Study shows effectiveness of gene therapy in treating congenital deafness

Rice scientists identify promising new immunological pathway to treat breast cancer bone metastases

New study reveals effective strategies against drug resistance in hospital-acquired pneumonia treatment

Receptor protein found to be a key player in prostate cancer cells' drug resistance

Does space travel impact the human reproductive system?

Unveiling the cellular mechanisms of engram consolidation and memory refinement

Important discovery could lead to novel treatment for obesity

New structural insights pave the way for drug-resistant malaria therapies

Understanding antimicrobial resistance in hospital-acquired pneumonia

New targeted therapy eliminates cancer with zero side effects

Monkey study points to HIV vulnerability for vaccine attack

Urea-powered nanorobots reduce bladder tumors by 90% in mice

Research team develops electrostatic materials for long-term bio-implants

New drug screening system helps uncover promising target for pancreatic cancer treatments

Stem cell heart tissue model paves the way for better understanding of tachycardia

Novel molecular link between vitamin B12 and multiple sclerosis revealed in astrocytes

Promising candidate medication for preventing and reversing fentanyl-induced overdose

Neuroimaging and network modeling tools shed light on Alzheimer's disease in animal models

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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