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New protein could offer a fresh target for cancer treatment

A study has revealed a drug target called the mitoNEET cell protein, which determines how materials are transported from the mitochondria to the rest of the cell.

19 Sep 2019

Using anion exchange chromatography and electrochemical detection for determination of carbohydrates

Carbohydrates are among the most widespread organic compounds in the living nature. As monosaccharides and di-saccharides, they primarily serve the direct supply of energy in the organism. In the form of oligomers or polymers, they are used more for storage of energy or information, or take over tasks as a structural element in cell walls, primarily of plants.

From KNAUER Wissenschaftliche Geräte GmbH 3 Sep 2019

Researchers identify new transmembrane protein as chloride ion channel

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems.

14 Aug 2019

Researchers use metal-free catalyst to synthesize ketone from aldehyde

Ketones are important organic compounds found in a variety of pharmaceuticals, agrochemicals, and natural products.

4 Apr 2019

KNAUER introduces new Sepapure FPLC columns and media for protein purification tasks

The new Sepapure columns and media represent high-quality alternatives for common protein purification tasks like size-exclusion, affinity and ion-exchange chromatography.

From KNAUER Wissenschaftliche Geräte GmbH 21 Mar 2019

Researchers discover facile method for introduction of fluorine atoms into organic molecules

The vast majority of pharmaceuticals employed in the treatment of human diseases are of an organic nature, meaning that the active component is a molecule (or a combination of several molecules) that is constituted of carbon and hydrogen atoms.

6 Mar 2019

New green, economical way achieves key organic synthesis via catalyst synergy

In organic chemistry, discovering new reactions is one thing, but to carry them off efficiently is quite another. Carbon-carbon bond-forming is at the heart of organic synthesis, allowing us to stitch together diverse functional groups into an endless array of useful compounds.

26 Feb 2019

Novel method accelerates development of drugs

One of the key steps in developing new drugs is determining the atomic structure of its biologically active substances. This generally involves performing X-ray analyses of single crystal structures to determine the ingredient's detailed three-dimensional set-up. However, growing suitable single crystals is often a complex and time-consuming process.

26 Mar 2018

Russian scientists design new compounds that can treat glaucoma

Glaucoma is a serious disease associated with increased intraocular pressure which often leads to blindness. One of the ways to treat glaucoma is to reduce aqueous humour secretion in the ciliary body of the eye by suppressing (inhibiting) activity of special enzymes - carbonic anhydrases.

3 Nov 2017

Sartorius Stedim Biotech launches new Sartobind Cassettes for commercial applications

Sartorius Stedim Biotech, a leading international supplier for the biopharmaceutical industry, has expanded its range of single-use membrane chromatography solutions with Sartobind Cassettes.

From Sartorius 11 Sep 2017

Protein distribution channel may be new target for combating pathogenic bacterium

A bacterium that attacks people suffering from chronic lung disease and compromised immune systems could be halted by disrupting the distribution channels the organism uses to access the nutrient-rich cytoplasm of its host cell.

31 Aug 2017

Researchers examine cheap, simple method for neurotoxin detection

There is a limited amount of data on the global health impacts of pesticides, but many injuries and deaths worldwide can be attributed to their misuse.

1 Aug 2017

Zirconia-doped ceria nanoparticles can act as effective antioxidants in sepsis treatment

During sepsis, cells are swamped with reactive oxygen species generated in an aberrant response of the immune system to a local infection.

6 Jul 2017

Single-molecule compounds may become basis for new antioxidant therapies

Treated particles of graphene derived from carbon nanotubes have demonstrated remarkable potential as life-saving antioxidants, but as small as they are, something even smaller had to be created to figure out why they work so well.

28 Jan 2017

Switching off brain regions helps better understand link between neural circuits and behaviour

Switching off specific brain regions in a laboratory animal is an important type of experiment used to better understand how the brain works.

24 Jan 2017

Porous acupuncture needles use nanotechnology to offer improved therapeutic properties

A DGIST research team led by Professor Su-Il In, who developed acupuncture needles combined with nanotechnology, was recognized as the world's first application of this technology.

18 Oct 2016

Factors secreted by intestinal bacteria may help prevent or treat kidney stones

Researchers have discovered that factors secreted by gut bacteria might help prevent or treat kidney stones.

14 Oct 2016

Researchers find new insights on disease stages for gastric cancer patients

Diagnosis of gastric cancer in the early stages is difficult because of the lack of simple and cheap methods of inspection and specific markers of gastric cancer while the symptoms of the disease are vague and tend to overlap with other common and benign conditions. Better tumor characterization and more individualized treatment planning can be expected only with the implementation of better diagnostic tools combined with advances in molecular and genetic analysis.

21 Apr 2016

TSRI scientists reveal workings of key 'relief-valve' in cells

A team led by scientists at The Scripps Research Institute has solved a long-standing mystery in cell biology by showing essentially how a key "relief-valve" in cells does its job.

30 Jan 2016

UTHealth researchers discover new light-activated proteins that work as 'off switches' for brain cells

Light switches for neurons have made enormous contributions to brain research by giving investigators access to "on switches" for brain cells. But, finding "off switches" has been much more challenging.

2 Jul 2015