Anthracycline News and Research

RSS

Anthracycline is a type of antibiotic that comes from certain types of Streptomyces bacteria. Anthracyclines are used to treat many types of cancer. Anthracyclines damage the DNA in cancer cells, causing them to die. Daunorubicin, doxorubicin, and epirubicin are anthracyclines.

DASH diet may lower the risk of cardiovascular disease in breast cancer survivors

A new paper in JNCI Cancer Spectrum, published by Oxford University Press, finds that following a healthy diet lowers the risk of cardiovascular disease in breast cancer survivors.

17 Apr 2024

ACE inhibitors show no benefit in reducing chemotherapy-induced heart damage

Patients who took an angiotensin-converting enzyme (ACE) inhibitor while undergoing cancer treatment with high-dose anthracycline chemotherapy did not show any difference in troponin T levels, a biomarker associated with heart damage, at one month after their last chemotherapy dose compared with those who did not take an ACE inhibitor, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Genetic test can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy

Researchers have developed a genetic test that can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy drugs.

20 Mar 2024

Simple biomarkers offer early warning of hidden heart risk in childhood cancer survivors

Data from the St. Jude lifetime cohort study (St. Jude LIFE) revealed that two common biomarkers of cardiac function and damage could better predict cardiomyopathy within five years than routine clinical evaluations in high-risk, asymptomatic childhood cancer survivors.

11 Jan 2024

Carvedilol improves heart health marker in childhood cancer survivors

Physicians at City of Hope, one of the largest cancer research and treatment organizations in the United States, in cooperation with the Children's Oncology Group (COG), have conducted the largest clinical trial to date seeking to reduce the risk of people who have survived childhood cancer from developing heart failure.

9 Jan 2024

Childhood cancer treatment linked to higher breast cancer risk

Women who have been treated for cancer as a child with a certain type of chemotherapy have an increased risk of breast cancer, according to a large-scale international study of survivors of childhood cancer led by scientists from the Princess Máxima Center for pediatric oncology.

11 Sep 2023

ER-phagy alleviates drug-induced cardiomyopathy in cancer patients

A cell contains many specialized subunits, called organelles, that carry out important tasks such as energy generation, protein synthesis, and calcium outflux. But what happens when something goes wrong with one of the organelles?

31 Aug 2023

Case report and review of a novel chromosomal abnormality in AML patient

A new research paper was published in Genes & Cancer on June 28, 2023, entitled, "A novel t (5; 17) (q35; q21) associated with t (8; 21) (q22; q22) in a patient with acute myeloid leukemia: case report and review of literature."

7 Jul 2023

Young adult cancer survivors at higher risk of heart failure when treated with anthracyclines

Imagine surviving cancer only to learn the drug that saved your life has introduced a completely different health risk: heart failure.

16 May 2023

ACC to host annual Advancing the Cardiovascular Care of the Oncology Patient course

The American College of Cardiology will host the annual Advancing the Cardiovascular Care of the Oncology Patient course on April 14-16, 2023, in Washington, DC.

10 Apr 2023

Researchers discover a protein linked with the onset of anthracycline-associated cardiac toxicity

Anthracyclines are a class of chemotherapies effective in treating many forms of cancer, including leukemias, lymphomas and breast cancer.

27 Dec 2022

IU researchers uncover new ways to prevent serious side effects for breast cancer patients

Researchers at Indiana University School of Medicine are learning more about ways to prevent serious side effects from chemotherapy used to treat breast cancer patients.

20 Dec 2022

Inhibiting inflammatory signaling pathway could reduce the chances of heart disease in cancer survivors

Researchers at Memorial Sloan Kettering Cancer Center (MSKCC) in New York have discovered that common cancer treatments, such as radiotherapy or anthracycline drugs, cause long-term damage to heart tissue by activating a key inflammatory signaling pathway.

19 Dec 2022

Penn State researchers lay the foundation for precision fabrication of tumor models

Researchers at Penn State have successfully 3D bioprinted breast cancer tumors and treated them in a breakthrough study to better understand the disease that is one of the leading causes of mortality worldwide.

18 Oct 2022

Did the diagnosis and management of Hodgkin lymphoma differ during the SARS-CoV-2 pandemic?

In a new study, researchers evaluated the impact of the SARS-CoV-2 pandemic on the diagnosis and treatment of classical Hodgkin lymphoma (cHL) patients in Istanbul, Turkey.

17 Oct 2022

Study estimates the cost-effectiveness of therapeutic alternatives

Giving standard chemotherapy drugs in a specific sequence for some types of metastatic breast cancer can help reduce overall costs and improve the value of care while preserving quality of life, according to a study led by UNC Lineberger Comprehensive Cancer Center and UNC Gillings School of Global Public Health researchers.

14 Sep 2022

New advice aims to reduce the cardiac side effects of cancer treatment

The first European Society of Cardiology Guideline on cardio-oncology is published online today in European Heart Journal.

26 Aug 2022

Machine learning and proteomics predict cardiovascular risk more accurately

An innovative proteomics-based model that predicts the risk of cardiovascular events with higher accuracy than current clinical models.

10 Apr 2022

Vitamin C may help to counteract common side effect of the chemotherapy drug

A study conducted in rats suggests that taking vitamin C may help to counteract the muscle atrophy that is a common side effect of the chemotherapy drug doxorubicin.

4 Apr 2022

Study uncovers a gene that strongly associates with breast cancer patient's treatment outcomes

A multidisciplinary team of researchers from Roswell Park Comprehensive Cancer Center and Kaiser Permanente Northern California have identified the first pharmacogenomic marker for anthracyclines and HER2-targeting drugs, two commonly used breast cancer chemotherapies.

23 Mar 2022