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Itaconate can suppress pro-inflammatory activity of macrophages

Itaconate can suppress pro-inflammatory activity of macrophages

An international group of scientists from US, Canada, Germany and Russia has revealed a substance produced in humans that can suppress the pro-inflammatory activity of macrophages - specific cells of immune system. [More]
Scientists detect biological markers of chronic fatigue syndrome in gut bacteria

Scientists detect biological markers of chronic fatigue syndrome in gut bacteria

Physicians have been mystified by chronic fatigue syndrome, a condition where normal exertion leads to debilitating fatigue that isn't alleviated by rest. There are no known triggers, and diagnosis requires lengthy tests administered by an expert. [More]
Two simple measures can help decrease incidence of POCD in older patients

Two simple measures can help decrease incidence of POCD in older patients

Post-operative cognitive dysfunction (POCD), a condition mostly observed in older patients following surgery under general anesthesia, is characterized by impaired memory and concentration. The impairment may be temporary or permanent and incapacitating. [More]
Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from the American Pain Society. [More]
Inflammatory response to mosquito bites can help spread viral infections

Inflammatory response to mosquito bites can help spread viral infections

Mosquito bite sites are not just itchy, irritating nuisances - they also make viral infections spread by the insects far worse, new research has found. [More]
Food allergies linked to diet and gut microbiome

Food allergies linked to diet and gut microbiome

The development of food allergies in mice can be linked to what their gut bacteria are being fed, reports a study published June 21 in Cell Reports. Rodents that received a diet with average calories, sugar, and fiber content from birth were shown to have more severe peanut allergies than those that received a high-fiber diet. [More]
Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

Cardiac surgery patients who received omega-3 supplementation experience reduced hospital stays

A new meta-analysis published in Clinical Nutrition found that cardiac surgery patients who received omega-3 polyunsaturated fatty acids (compared to placebo) in advance of surgery experienced reduced postoperative cardiac arrhythmias and significantly reduced the length of hospital stay by up to 2.4 days. The results are based on 11 RCT's with 1038 patients. [More]
Study shows childhood adversities, sleep disturbances interfere with immune system regulation

Study shows childhood adversities, sleep disturbances interfere with immune system regulation

Adverse childhood experiences and sleep disturbances interfere with immune system regulation, shows research from the University of Eastern Finland. [More]
Study finds link between chronic inflammation and premenstrual symptoms

Study finds link between chronic inflammation and premenstrual symptoms

Women with premenstrual symptoms (PMS) including mood swings, weight gain/bloating, and abdominal cramps/back pain have elevated levels of C-reactive protein (CRP), a biomarker of inflammation associated with increased risk of cardiovascular disease. [More]
Statins can lower infection risk by 58% in stroke patients

Statins can lower infection risk by 58% in stroke patients

A Washington State University researcher has found that statin drugs can dramatically lower the risk of infections in stroke patients. [More]
Nut consumption may lower risk of overall mortality in prostate cancer patients

Nut consumption may lower risk of overall mortality in prostate cancer patients

In a large prospective study published online in the British Journal of Cancer, researchers looked at the association between nut consumption and prostate cancer risk and mortality among 47,299 men in the Health Professionals Follow-up Study. [More]
Researchers find unexpected connection between two types of calming immune cells

Researchers find unexpected connection between two types of calming immune cells

Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit our guts pose a constant risk of infection--and all that separates us from these foreign entities is a delicate boundary made of a single layer of cells. [More]
Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

Metabolite of oral DMF drug for multiple sclerosis appears to slow onset of Parkinson's disease

The metabolite of a drug that is helping patients battle multiple sclerosis appears to significantly slow the onset of Parkinson's disease, researchers say. [More]
Age may play major role in cell's ability to respond to physical exercise

Age may play major role in cell's ability to respond to physical exercise

If you're an older adult, a 30-minute workout may not be as effective, even at the cellular level, as it was when you were younger. [More]
B lymphocytes can influence psoriasis by regulating cytokine IL-10

B lymphocytes can influence psoriasis by regulating cytokine IL-10

"A pathological and very complex autoimmune reaction of the skin": This is the definition doctors and scientists use to describe psoriasis, a disease that affects one to three percent of the population. [More]
Ways to prevent, treat knee and hip joint pain

Ways to prevent, treat knee and hip joint pain

In the past four weeks, more than one-third of people over the age of 55 in the United States have complained about hip or knee pain to their physician. In a lifetime, our hips and knees get a lot of use. There are various ways individuals can reduce the strain placed on their joints to maintain the health of their hips and knees. [More]
Rice study takes deeper look at how inflammation bridges stress and diabetes

Rice study takes deeper look at how inflammation bridges stress and diabetes

A Rice University study has found a link between emotional stress and diabetes, with roots in the brain's ability to control anxiety. [More]
Myricitrin may play role in preventing neuronal degeneration in Parkinson's disease

Myricitrin may play role in preventing neuronal degeneration in Parkinson's disease

A new study has shown that myricitrin, a flavinoid with antioxidant and anti-inflammatory activity that is present inedible plants and fruit, can protect mouse brains from the loss of dopamine-producing neurons caused by neurotoxicity. [More]
Neutral atherosclerosis trial highlights effectiveness of optimal medical therapy

Neutral atherosclerosis trial highlights effectiveness of optimal medical therapy

Salsalate has no greater effect than placebo on the progression of coronary artery plaque, show the findings of the randomised TINSAL-CVD trial. [More]
Gut microbe's metabolite butyrate hampers intestinal repair from IBD

Gut microbe's metabolite butyrate hampers intestinal repair from IBD

Intestinal stem cells are among the most rapidly dividing cells in the body, busily creating new cells to replace the ones that are constantly being sloughed off. But unlike stem cells elsewhere in the body, those in the intestine are hidden away, and for good reason, it turns out. [More]
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