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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.
Researchers discover how bacterial enzyme can blunt the body's key immune defenses

Researchers discover how bacterial enzyme can blunt the body's key immune defenses

Scientists have discovered how a unique bacterial enzyme can blunt the body's key weapons in its fight against infection. [More]
New guidelines provide recommendations for prevention and management of surgical site infections

New guidelines provide recommendations for prevention and management of surgical site infections

A Loyola Medicine surgeon is first author of new guidelines for the prevention, detection and management of surgical site infections, which affect as many as 300,000 patients per year in the United States. [More]
OSU scientists develop new weapon to combat antibiotic-resistant germs

OSU scientists develop new weapon to combat antibiotic-resistant germs

Oregon State University researchers have developed a new weapon in the battle against antibiotic-resistant germs - a molecule that neutralizes the bugs' ability to destroy the antibiotic. [More]
Improving fungal disease diagnostics could help battle against antimicrobial resistance

Improving fungal disease diagnostics could help battle against antimicrobial resistance

Ignorance of fungal disease and lack of diagnostics across the world is causing doctors to unknowingly overprescribe antibiotics a new report warns. [More]
Better fungal disease diagnostics could be critical to fight against antimicrobial resistance

Better fungal disease diagnostics could be critical to fight against antimicrobial resistance

Poor diagnosis worldwide of fungal disease causes doctors to overprescribe antibiotics, increasing harmful resistance to antimicrobial drugs, according to a paper published today in Emerging Infectious Diseases. [More]
Researchers unravel bacterial protein structure that could pave way for new antibiotics

Researchers unravel bacterial protein structure that could pave way for new antibiotics

Bacterial cells have an added layer of protection, called the cell wall, that animal cells don't. Assembling this tough armor entails multiple steps, some of which are targeted by antibiotics like penicillin and vancomycin. [More]
Researchers finding way to manipulate signals in bacteria to reduce infections

Researchers finding way to manipulate signals in bacteria to reduce infections

The University of Illinois at Chicago College of Pharmacy has received a five-year, $1.25 million federal grant to continue its research into how bacteria that cause streptococcal infections can be manipulated. [More]
New method provides rapid, accurate assessment of bacterial oxygen consumption in microdroplets

New method provides rapid, accurate assessment of bacterial oxygen consumption in microdroplets

In the future, it will be possible to carry out tests of new drugs on bacteria much more efficiently using microfluidic devices, since each of the hundreds and thousands of droplets moving through the microchannels can act as separate incubators. [More]
Study shows how phage-resistant cells become susceptible upon co-incubation with sensitive bacteria

Study shows how phage-resistant cells become susceptible upon co-incubation with sensitive bacteria

Bacteriophages (phages) are probably the most abundant entities in nature, often exceeding bacterial densities by an order of magnitude. [More]
New research paves way for better strategies to diagnose and manage vascular graft infections

New research paves way for better strategies to diagnose and manage vascular graft infections

A rising prevalence of cardiovascular disease has generated substantial growth in the use of medical implants, such as vascular grafts. [More]
Researchers provide insights into how phages exhibit high level of precision in cell destruction

Researchers provide insights into how phages exhibit high level of precision in cell destruction

Phage therapy, which exploits the ability of certain viruses to infect and replicate within bacteria, shows promise for treating antibiotic-resistant bacterial infections. [More]
Antibiotics targeting brain’s inflammatory response may exacerbate cognitive deficits in children

Antibiotics targeting brain’s inflammatory response may exacerbate cognitive deficits in children

Traumatic brain injury (TBI) is one of the leading causes of disability and death in infants and children in the United States, with more than half a million affected annually, according to the Centers for Disease Control and Prevention. [More]
PCT screening could be promising tool to help shorten hospital stays, reduce costs for sepsis patients

PCT screening could be promising tool to help shorten hospital stays, reduce costs for sepsis patients

Each year, over $20 billion dollars is spent on sepsis care, making it the most expensive condition managed in U.S. hospitals. [More]
Common viruses pose serious challenges in long-term care facilities

Common viruses pose serious challenges in long-term care facilities

A widespread outbreak of respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) at a long-term dementia care ward infected 73 percent of patients, demonstrating the serious challenges in mitigating the spread of infectious diseases in such settings. [More]
Researchers provide clues to how mcr-1 gene protects bacteria from 'last resort' antibiotic

Researchers provide clues to how mcr-1 gene protects bacteria from 'last resort' antibiotic

An international research team, led by the University of Bristol, has provided the first clues to understand how the mcr-1 gene protects bacteria from colistin - a 'last resort' antibiotic used to treat life-threatening bacterial infections that do not respond to other treatment options. [More]
Scientists develop technique to produce antibiotic synthetic spider silk

Scientists develop technique to produce antibiotic synthetic spider silk

A chance meeting between a spider expert and a chemist has led to the development of antibiotic synthetic spider silk. [More]
Scientists harness therapeutic effects of CO-RMs to develop new antibiotic for gonorrhoea

Scientists harness therapeutic effects of CO-RMs to develop new antibiotic for gonorrhoea

Scientists at the University of York have harnessed the therapeutic effects of carbon monoxide-releasing molecules to develop a new antibiotic which could be used to treat the sexually transmitted infection gonorrhoea. [More]
Persistent infection in infant reveals mutation that helps bacteria tolerate antibiotic therapy

Persistent infection in infant reveals mutation that helps bacteria tolerate antibiotic therapy

The quest to understand a prolonged infection in an infant being treated for leukemia has led to the St. Jude Children's Research Hospital discovery of a mutation that allows bacteria to tolerate normally effective antibiotic therapy. The report appears today in the scientific journal mBio. [More]
Research reveals how microbial context during infectious disease can compromise antibiotic therapy

Research reveals how microbial context during infectious disease can compromise antibiotic therapy

Bacteria that are susceptible to antibiotics can survive when enough resistant cells around them are expressing an antibiotic-deactivating factor. [More]
Genomic sequencing reveals new insights into major shigellosis outbreaks in California

Genomic sequencing reveals new insights into major shigellosis outbreaks in California

In a study that could have significant impact on how disease outbreaks are managed, researchers at UC Davis and the California Department of Public Health have sequenced and analyzed genomes from Shigella sonnei (S. sonnei) bacteria associated with major shigellosis outbreaks in California in 2014 and 2015. [More]
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