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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.
UMass Amherst biologist partners with Chinese scientist to develop novel drug platform

UMass Amherst biologist partners with Chinese scientist to develop novel drug platform

Margaret Riley, an evolutionary biologist at the University of Massachusetts Amherst and pioneer in fighting antibiotic-resistant bacteria, announced this week that she is partnering with a Chinese scientist to develop a new drug platform, pheromonicins. The Chinese government is committing $400 million per year to support the newly created Pheromonicin Institute of Beijing. [More]
Study reveals causes of community-acquired pneumonia in children

Study reveals causes of community-acquired pneumonia in children

With the chill of winter comes a spike in community-acquired pneumonia (CAP), which spreads more easily as people retreat indoors and come into close contact. The lung infection triggers persistent coughing, chest pain, fever, and difficulty breathing, and is particularly hard on the very young and the very old. In fact, pneumonia is the leading cause of hospitalization among U.S. children, with estimated medical costs of $1 billion annually. [More]
Study points respiratory viruses as the most common cause of childhood pneumonia

Study points respiratory viruses as the most common cause of childhood pneumonia

Respiratory viruses, not bacterial infections, are the most commonly detected causes of community-acquired pneumonia in children, according to new research released Feb. 26 in the New England Journal of Medicine. [More]
Garlic compound can help fight lung infections in people with cystic fibrosis

Garlic compound can help fight lung infections in people with cystic fibrosis

A chemical found in garlic can kill bacteria that cause life-threatening lung infections in people with cystic fibrosis, research suggests. [More]
Study suggests that antibiotics can induce potentially dangerous biofilm formation

Study suggests that antibiotics can induce potentially dangerous biofilm formation

Most people have taken an antibiotic to treat a bacterial infection. Now researchers from the University of North Carolina at Chapel Hill and the University of San Diego, La Jolla, reveal that the way we often think about antibiotics - as straightforward killing machines - needs to be revised. [More]

MRIGlobal awarded contract to develop Sample-to-Sequence system for diagnosis of infectious diseases

MRIGlobal today announced that it has been awarded a $14.8 million contract to develop an end-to-end next generation sequencing system for clinical diagnosis of infectious diseases. [More]
Researchers reveal how C. difficile wreaks havoc on guts, causes life-threatening diseases

Researchers reveal how C. difficile wreaks havoc on guts, causes life-threatening diseases

In a new paper in the journal Infection and Immunity, the researchers lay out for the first time exactly how C. difficile wreaks havoc on the guts of animals in a short time, and causes severe diarrhea and life-threatening disease in humans. [More]
NICE measures for resisting microbial drug resistance

NICE measures for resisting microbial drug resistance

NICE has published draft guidelines to ensure that antibiotics continue to be effective in treating infections and are not rendered useless through the development of antimicrobial resistance. [More]
Actavis provides overview of standalone global pharmaceutical development pipeline

Actavis provides overview of standalone global pharmaceutical development pipeline

Actavis plc, during its Investor Meeting in New York, today provided a detailed look into its standalone global pharmaceutical development pipeline that supports the Company's long-term organic growth. The Company provided details regarding key development programs, including clinical data, development milestones and an overview of potential market opportunities, as well as an updated look at Actavis' world-class generics pipeline, which continues to hold an industry-leading position in First-to-File opportunities in the U.S. [More]
Corticosteroids decrease treatment failure among patients with community-acquired pneumonia

Corticosteroids decrease treatment failure among patients with community-acquired pneumonia

Among patients with severe community-acquired pneumonia and high initial inflammatory response, the use of the corticosteroid methylprednisolone decreased treatment failure, compared with placebo, according to a study in the February 17 issue of JAMA. [More]

Rivers, streams could be a major source of antibiotic resistance in the environment

Rivers and streams could be a major source of antibiotic resistance in the environment. The discovery comes following a study on the Thames river by scientists at the University of Warwick's School of Life Sciences and the University of Exeter Medical School. [More]
Fusobacterium necrophorum often causes severe sore throats in young adults

Fusobacterium necrophorum often causes severe sore throats in young adults

New research from the University of Alabama at Birmingham suggests that Fusobacterium necrophorum more often causes severe sore throats in young adults than streptococcus — the cause of the much better known strep throat. [More]
ASU to host inaugural meeting for brand new scientific society in Tempe, Arizona

ASU to host inaugural meeting for brand new scientific society in Tempe, Arizona

Arizona State University will host a premiere opportunity to engage and mingle with luminaries in the burgeoning field of evolutionary medicine, a new interdisciplinary approach that is becoming an essential perspective in our view of disease, today's medical practice and the worldwide impact on public health as it hosts the Inaugural International Society for Evolution, Medicine & Public Health Meeting, March 19-21, 2015 in Tempe, Arizona. [More]
Medical practitioners rarely prescribe proper treatments for childhood diarrhea, pneumonia in rural India

Medical practitioners rarely prescribe proper treatments for childhood diarrhea, pneumonia in rural India

Few health care providers in rural India know the correct treatments for childhood diarrhea and pneumonia - two leading killers of young children worldwide. But even when they do, they rarely prescribe them properly, according to a new Duke University study. [More]
OSU researchers discover impact of antibiotics on microorganisms that live in animal's gut

OSU researchers discover impact of antibiotics on microorganisms that live in animal's gut

Researchers at Oregon State University have discovered that antibiotics have an impact on the microorganisms that live in an animal's gut that's more broad and complex than previously known. [More]
Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, today announced positive topline safety and tolerability results from a Phase 1b clinical trial of SYN-004, the Company's investigational oral beta-lactamase enzyme designed to protect the microbiome and prevent Clostridium difficile (C. difficile) infection, antibiotic-associated diarrhea and secondary antibiotic-resistant infections in patients receiving intravenous (IV) beta-lactam antibiotic therapy. [More]
IU researchers awarded NIH grant to develop new weapon to fight against antibiotic-resistant bacteria

IU researchers awarded NIH grant to develop new weapon to fight against antibiotic-resistant bacteria

The alarming increase of antibiotic-resistant bacteria poses health and economic threats worldwide, with more than 2 million Americans infected by the bacteria each year. Now, a team of Indiana University chemists and biologists has been awarded a major grant to develop and use a chemical tagging method to better understand how bacteria build their cell wall, which is still the best target for new antibiotics. [More]
Risks and benefits of fecal microbiota transplant

Risks and benefits of fecal microbiota transplant

A woman successfully treated for a recurrent Clostridium difficile infection with stool from an overweight donor rapidly gained weight herself afterwards, becoming obese, according to a case report published in the new journal Open Forum Infectious Diseases. [More]
Investigators develop microbiome map of New York City subway system

Investigators develop microbiome map of New York City subway system

The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs -- and even DNA fragments associated with anthrax and Bubonic plague -- according to a citywide microbiome map published today by Weill Cornell Medical College investigators. [More]
Researchers assess causes of febrile illnesses in Tanzanian children

Researchers assess causes of febrile illnesses in Tanzanian children

Valérie D'Acremont led the research team from the Swiss Tropical and Public Health Institute in Basel and the Policlinique Médicale Universitaire in Lausanne, who systematically assessed the causes of febrile illnesses in Tanzanian children. According to the published paper, in most cases a treatment with antimalarials or antibiotics is not required. [More]