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Duke researchers modify popular drug-delivery technology to evade immune responses

Duke researchers modify popular drug-delivery technology to evade immune responses

Biomedical engineers at Duke University have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials. [More]
New self-regulating smart patch releases blood-thinning drugs when necessary

New self-regulating smart patch releases blood-thinning drugs when necessary

An interdisciplinary team of researchers has developed a smart patch designed to monitor a patient's blood and release blood-thinning drugs as needed to prevent the occurrence of dangerous blood clots - a condition known as thrombosis. [More]
Atrial fibrillation patients treated with anticoagulant drug have higher risk of developing dementia

Atrial fibrillation patients treated with anticoagulant drug have higher risk of developing dementia

Atrial fibrillation patients who use the drug, warfarin, to prevent harmful blood clots from forming in their hearts to lower risk of stroke are at higher risk of developing dementia than patients who use warfarin for non-atrial fibrillation conditions, according to a new study from the Intermountain Medical Center Heart Institute. [More]
Research finds low rates of oral anticoagulant use in hospitalized atrial fibrillation patients

Research finds low rates of oral anticoagulant use in hospitalized atrial fibrillation patients

When patients suffer from atrial fibrillation, an irregular heartbeat, they are at considerably higher risk for blood clots and stroke. [More]
New treatment strategy effective in preventing bleeding in AF patients who underwent PCI, study shows

New treatment strategy effective in preventing bleeding in AF patients who underwent PCI, study shows

A new study led by clinician-researchers at Beth Israel Deaconess Medical Center testing the safety and effectiveness of anticoagulant strategies for patients with atrial fibrillation who undergo stenting procedures has shown that therapies combining the anticoagulant drug rivaroxaban with either single or dual anti-platelet therapy were more effective in preventing bleeding complications than the current standard of care. [More]
Genetic susceptibility could help identify breast cancer patients at risk of developing VTE

Genetic susceptibility could help identify breast cancer patients at risk of developing VTE

Genetic testing could help identify breast cancer patients with high risk of experiencing venous thromboembolism (VTE), a serious and potentially fatal complication that can occur during cancer treatment. [More]
Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

As demand for the widely used blood thinning drug heparin continues to grow, experts worry of possible shortages of the essential medication. [More]
NCDR provides data to study appropriate use of oral anticoagulant therapy

NCDR provides data to study appropriate use of oral anticoagulant therapy

The American College of Cardiology's National Cardiovascular Data Registry was the source of data for research published throughout 2016, including a study examining if atrial fibrillation patients are being prescribed oral anticoagulants, how appropriate use criteria correlates to angioplasty rates and the variation among racial groups for revascularization procedures. [More]
Scientists use novel theranostics technique for early thromboembolism diagnosis and treatment

Scientists use novel theranostics technique for early thromboembolism diagnosis and treatment

Researchers from the University of Arkansas for Medical Science (USA), in collaboration with University Hospital Frankfurt and University Hospital Dresden, under the supervision of Prof. Vladimir Zharov and with the participation of Alexander Melerzanov, the dean of Department of Biological and Medical Physics (MIPT), conducted experiments on mice to detect blood clotting using photoacoustic flow-cytometry. [More]
Inhealthcare introduces first self-testing mobile app for warfarin users

Inhealthcare introduces first self-testing mobile app for warfarin users

Digital health specialist Inhealthcare is bringing to market the first self-testing mobile app for warfarin users that connects directly to doctors. [More]
Clinical review of patients with atrial fibrillation prevents hundreds of strokes, saves NHS millions of pounds

Clinical review of patients with atrial fibrillation prevents hundreds of strokes, saves NHS millions of pounds

A review of 135,000 patients with atrial fibrillation (AF) at more than a 1,000 GP practices led to over 25,000 medical interventions, which is believed to have prevented hundreds of strokes and saved the NHS millions of pounds. [More]
Researchers discover risk factors that contribute to fracture nonunion in adults

Researchers discover risk factors that contribute to fracture nonunion in adults

Dr. Robert Zura, the Robert D'Ambrosia Professor and Head of Orthopaedic Surgery at LSU Health New Orleans School of Medicine, was part of a research team that identified risk factors which may help orthopaedic surgeons better predict a serious complication of bone fractures. [More]
REVERSE II trial validates HERDOO2 rule to help spot women who can discontinue anticoagulants

REVERSE II trial validates HERDOO2 rule to help spot women who can discontinue anticoagulants

A clinical decision rule (CDR) that can be applied to women after a first, unprovoked venous thromboembolism (VTE) was able to identify those with a low-risk of recurrence who could safely discontinue anticoagulant therapy, researchers reported at ESC Congress 2016. [More]
New anticoagulant treatment safe and effective for AF patients before cardioversion

New anticoagulant treatment safe and effective for AF patients before cardioversion

Patients with atrial fibrillation (AF) who need anticoagulation before undergoing electrical correction of their abnormal heartbeat (cardioversion) may benefit from treatment with edoxoban - a non-vitamin K antagonist (VKA) oral anticoagulant (NOAC), according to results of the ENSURE-AF trial. [More]
Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

A specially designed antidote to reverse acute, potentially life-threatening anticoagulant-related bleeding worked quickly, and was well-tolerated according to interim results of the ongoing ANNEXA-4 study. [More]
Alcohol-related hospitalisation linked to increased risk of ischaemic stroke in atrial fibrillation patients

Alcohol-related hospitalisation linked to increased risk of ischaemic stroke in atrial fibrillation patients

Alcohol related hospitalisation is associated with a doubled risk of ischaemic stroke risk in patients with non-valvular atrial fibrillation, according to a study presented at ESC Congress 2016 today by Dr Faris Al-Khalili, cardiologist, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden. [More]
First ESC Guidelines on Atrial Fibrillation published online

First ESC Guidelines on Atrial Fibrillation published online

The first European Society of Cardiology (ESC) Guidelines on Atrial Fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS) are published online today in European Heart Journal and the European Journal of Cardio-Thoracic Surgery, and on the ESC Website. [More]
Updated AAN guidelines state closure not recommended for individuals with stroke and heart defect

Updated AAN guidelines state closure not recommended for individuals with stroke and heart defect

An updated recommendation from the American Academy of Neurology states that catheter-based closure should not be routinely recommended for people who have had a stroke and also have a heart defect called a patent foramen ovale (PFO), a channel between the top two chambers in the heart. [More]
Hematology researchers develop new bio-engineered clotting factor to control bleeding

Hematology researchers develop new bio-engineered clotting factor to control bleeding

Every five minutes someone in the U.S. dies from a blood clot, through its role in strokes, heart attacks or other severe conditions. [More]
UNC professor identifies research priorities to address VTE in cancer patients

UNC professor identifies research priorities to address VTE in cancer patients

More than 20 percent of all blood clots in veins occur in cancer patients. These clots, also known as venous thromboembolism (VTE), pose serious threats for cancer patients. [More]
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