Antidepressant News and Research RSS Feed - Antidepressant News and Research

Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.
Modulation of opioid system may improve effectiveness of drugs for treatment-resistant depression

Modulation of opioid system may improve effectiveness of drugs for treatment-resistant depression

A clinical trial of an experimental drug for treatment-resistant major depression finds that modulation of the endogenous opioid system may improve the effectiveness of drugs that target the action of serotonin and related monoamine neurotransmitters. [More]
Vanderbilt study offers a glimmer of hope to alcoholics suffering from depression

Vanderbilt study offers a glimmer of hope to alcoholics suffering from depression

A study by researchers at Vanderbilt University Medical Center is offering a glimmer of hope to alcoholics who find it hard to remain sober because their abstinence is hounded by stubborn, difficult-to-treat depression. [More]
Allergan's investigational medication rapastinel granted FDA Breakthrough Therapy designation

Allergan's investigational medication rapastinel granted FDA Breakthrough Therapy designation

Allergan plc., a leading global pharmaceutical company today announced that its Phase III ready investigational medication rapastinel (GLYX-13) received Breakthrough Therapy designation from the U.S. Food and Drug Administration for adjunctive treatment of Major Depressive Disorder (MDD). [More]
Mood disorder experts question effectiveness of metyrapone drug

Mood disorder experts question effectiveness of metyrapone drug

Pioneering research by mood disorder experts at Newcastle University has questioned the effectiveness of metyrapone, a drug suggested to treat depression. [More]
Depression in expectant parents during pregnancy increases risk of premature birth

Depression in expectant parents during pregnancy increases risk of premature birth

Depression in both expectant mothers and fathers increases the risk of premature birth, finds a study published in BJOG: an International Journal of Obstetrics and Gynaecology (BJOG). [More]
Rapastinel demonstrates pro-cognitive benefits in animal model of cognitive impairment

Rapastinel demonstrates pro-cognitive benefits in animal model of cognitive impairment

Allergan plc, a leading global pharmaceutical company, announced today that new data on the investigational medication rapastinel (GLYX-13) and its lack of impairment on cognitive function were published in the peer-reviewed journal Behavioural Brain Research. [More]
Inflammation associated with elevated glutamate in the brain could guide depression treatments

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Psychiatrists investigating depression have been energized in recent years by reports of rapid, successful treatment with drugs that interfere with the brain chemical glutamate, such as the anesthetic ketamine. [More]
CGP3466B compound may effectively treat depression

CGP3466B compound may effectively treat depression

The compound CGP3466B, already proven nontoxic for people, may effectively and rapidly treat depression, according to results of a study in mice. [More]
Johns Hopkins researchers show that stroke may increase brain plasticity, recovery in some cases

Johns Hopkins researchers show that stroke may increase brain plasticity, recovery in some cases

Using mice whose front paws were still partly disabled after an initial induced stroke, Johns Hopkins researchers report that inducing a second stroke nearby in their brains let them “rehab” the animals to successfully grab food pellets with those paws at pre-stroke efficiency. [More]
Researchers find no evidence that prenatal exposure to antidepressants increases risk for autism, ADHD

Researchers find no evidence that prenatal exposure to antidepressants increases risk for autism, ADHD

An analysis of medical records data from three Massachusetts health care systems finds no evidence that prenatal exposure to antidepressants increases the risk for autism and related disorders or for attention-deficit hyperactivity disorder (ADHD). [More]
Using antidepressant drug during first trimester of pregnancy may increase risk of birth defects

Using antidepressant drug during first trimester of pregnancy may increase risk of birth defects

Using paroxetine--a medication prescribed to treat conditions including depression, obsessive-compulsive disorder, anxiety and posttraumatic stress disorder--during the first trimester of pregnancy may increase newborns' risk of congenital malformations and cardiac malformations. That's the conclusion of a recent analysis published in the British Journal of Clinical Pharmacology. [More]
Yale researchers reveal why chronic overeating tied to increased risk of depression

Yale researchers reveal why chronic overeating tied to increased risk of depression

Chronic overeating and stress are tied to an increased risk of depression and anxiety, and in a new study, Yale researchers explain why that happens and suggest a possible solution. [More]
Using antidepressants during pregnancy greatly increases autism risk

Using antidepressants during pregnancy greatly increases autism risk

Using antidepressants during pregnancy greatly increases the risk of autism, Professor Anick Bérard of the University of Montreal and its affiliated CHU Sainte-Justine children's hospital revealed today. Prof. Bérard, an internationally renowned expert in the fields of pharmaceutical safety during pregnancy, came to her conclusions after reviewing data covering 145,456 pregnancies. [More]

Cognitive behavioral therapy can be equally effective as second generation antidepressant for depression

Major depressive disorder affects more than 32 million Americans, and their first stop for treatment is often their primary care provider. A recent evidence review of several alternatives to medication found that using cognitive behavioral therapy as the first treatment for depression can be equally effective as using a second generation antidepressant. [More]
Novel antidepressant appears to be safe, effective against depression in clinical trial

Novel antidepressant appears to be safe, effective against depression in clinical trial

A small clinical trial of a novel antidepressant that stimulates neurogenesis - the production of new brain cells - shows that the compound appears to be safe and may be effective against depression. [More]
Women with moderate-to-severe PMS at increased risk of developing high blood pressure in later life

Women with moderate-to-severe PMS at increased risk of developing high blood pressure in later life

In the first prospective study to consider premenstrual syndrome (PMS) as a possible sentinel for future risk of hypertension, epidemiologist Elizabeth Bertone-Johnson and colleagues in the School of Public Health and Health Sciences at the University of Massachusetts Amherst and the Harvard School of Public Health report that women with moderate-to-severe PMS had a 40 percent higher risk of developing high blood pressure over the following 20 years compared to women experiencing few menstrual symptoms. [More]
Misleading symptoms confuse management of older patients with post-HSE relapse

Misleading symptoms confuse management of older patients with post-HSE relapse

Research shows that teenagers and adults with immune-mediated relapse after herpes simplex encephalitis rarely display the symptoms typically seen in children, delaying the initiation of vital immunotherapy. [More]

Radiocarbon method proves Cameroon’s environment is contaminated with synthetic opioid

Tramadol, a synthetic opioid component of the painkiller tramal, was surprisingly identified in 2013 as a natural product of Sarcocephalus latifolia, a tree found in Cameroon. [More]
Study finds no consistent evidence that antidepressants increase complications after plastic surgery

Study finds no consistent evidence that antidepressants increase complications after plastic surgery

For patients undergoing plastic surgery procedures, there's no consistent evidence that taking antidepressants increases the risk of bleeding, breast cancer, or other adverse outcomes, concludes a research review in the November issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons. [More]

Risk of depression recurrence significantly lower for people with complete symptom resolution

People who have had an episode of major depression are at high risk for having another episode. Now, researchers at University of California, San Diego School of Medicine have found that the risk of recurrence is significantly lower for people with complete, rather than partial depressive symptom resolution. [More]
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