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Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Researchers from Lund University in Sweden have identified distinct molecular signatures associated with the clinical signs of sepsis that could provide more accurate diagnosis and prognosis of sepsis, as well as help to target specific therapies at patients who would benefit most, according to new research being presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April).

30 Mar 2024

Climate change heats up fungal threats worldwide

Review in The Lancet Microbe discusses how rising global temperatures enable fungi to adapt, becoming more thermotolerant and expanding into new areas, which may lead to an increased emergence of novel pathogens impacting socially vulnerable groups the most.

20 Mar 2024

Artichoke's health secret, traditional remedy to modern marvel

Study highlights the artichoke's nutritional benefits and its potential to improve cardiovascular health, exhibit neuroprotective effects, and offer antimicrobial properties, emphasizing its value beyond dietary use.

18 Mar 2024

Rising antifungal resistance heightens concerns over invasive fungal infections

A global wave of infections caused by fungi growing drug-resistant has the medical community issuing precautions on how to protect yourself.

18 Mar 2024

Unlocking quinoa's power: Beyond nutrition to drug development

Existing data on the bioactive constituents of quinoa and their health benefits.

18 Mar 2024

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

A new research perspective was published in Oncoscience (Volume 11) on February 7, 2024, entitled, "IPIAD- an augmentation regimen added to standard treatment of pancreatic ductal adenocarcinoma using already-marketed repurposed drugs irbesartan, pyrimethamine, itraconazole, azithromycin, and dapsone."

9 Feb 2024

Bladder and gut fermentation syndromes: Uncommon disorders with significant implications

Study reviews bladder fermentation syndrome (BFS) and gut fermentation syndrome (GFS), highlighting their etiology, diagnosis, and treatment, and emphasizing the importance of recognizing these conditions to avoid misinterpretation in abstinence monitoring.

23 Jan 2024

The role of glucose in inducing tolerance to amphotericin B for fungal meningitis treatment

Researchers investigate the mechanism responsible for amphotericin B tolerance of Cryptococcus neoformans.

18 Jan 2024

Asparagus root extracts emerge as promising natural emulsifiers and potential anti-obesity agents

Study in "Foods" journal characterizes saponin extracts from asparagus roots, highlighting their potential as natural emulsifiers and foaming agents in food and cosmetics, and their inhibitory activity against pancreatic lipase, suggesting anti-obesity applications.

16 Jan 2024

CDC report highlights urgent need for guideline adherence in prescribing antifungal medications

The CDC's study on Medicare Part D beneficiaries reveals high prescription rates and costs for topical antifungal medications, emphasizing the need for proper prescribing guidelines amid rising antimicrobial-resistant fungal infections.

16 Jan 2024

Drug-resistant Candida: Study uncovers evolutionary tricks of a fungal pathogen

Global fungal infections, which affect one billion people and cause 1.5 million deaths each year, are on the rise due to the increasing number of medical treatments that heighten vulnerability.

12 Jan 2024

Study reveals mangos attenuates potential against colon cancer

The chemo-preventive potential of Mangiferin (MF) (mango).

10 Jan 2024

Green tea-silver nanoparticles: A promising weapon against superbugs

Once upon a time, people believed to be invincible against bacterial diseases, thanks to the antibiotics. Does this sound like a fairy tale? By all means! Nothing could be further from the truth.

17 Nov 2023

Scientists discover kidney-friendly antifungal that evades resistance

In this investigation, researchers produced powerful antifungals of the polyene class without nephrotoxicity.

9 Nov 2023

New antifungal molecule shows promise in combatting fungal infections without toxicity

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug's power against fungal infections while doing away with its toxicity, researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Wisconsin-Madison report in the journal Nature.

8 Nov 2023

Seaweed symbionts reveal treasure trove of potential drug compounds

Marine macroalgae-associated Bacillota reveal a trove of bioactive compounds with potential pharmacological benefits, from antibacterial to anticancer properties. This comprehensive review illuminates the promising yet underexplored therapeutic applications of these marine microorganisms.

1 Nov 2023

Fighting invisible foes: How cryptic fungal pathogens threaten human health and food security

The research paper in PLOS Pathogens delves into the challenges of diagnosing and treating cryptic fungal pathogens, which are difficult to distinguish from common fungi but equally dangerous. The study calls for more accurate diagnostic methods and a better understanding of how these fungi interact with the human immune system and microbiome for effective treatment and prevention.

25 Oct 2023

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

24 Oct 2023

Can herbal remedies, spices, and dietary fibers offer effective treatment options for children with irritable bowel syndrome (IBS)?

The positive effects and adverse reactions of spices, dietary fiber, and medicinal herbs for pediatric patients with IBS.

16 Oct 2023

Could seaweeds be the superfood and medicine of the future?

Researchers consolidate the diverse nutritional and medicinal benefits of seaweeds, touting their potential in food, nutraceuticals, and pharmaceuticals. The study also highlights challenges and opportunities in industrial applications, calling for more research to optimize extraction and refinement processes.

2 Oct 2023

Antifungal News and Research

Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Climate change heats up fungal threats worldwide

Artichoke's health secret, traditional remedy to modern marvel

Rising antifungal resistance heightens concerns over invasive fungal infections

Unlocking quinoa's power: Beyond nutrition to drug development

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

Bladder and gut fermentation syndromes: Uncommon disorders with significant implications

The role of glucose in inducing tolerance to amphotericin B for fungal meningitis treatment

Asparagus root extracts emerge as promising natural emulsifiers and potential anti-obesity agents

CDC report highlights urgent need for guideline adherence in prescribing antifungal medications

Drug-resistant Candida: Study uncovers evolutionary tricks of a fungal pathogen

Study reveals mangos attenuates potential against colon cancer

Green tea-silver nanoparticles: A promising weapon against superbugs

Scientists discover kidney-friendly antifungal that evades resistance

New antifungal molecule shows promise in combatting fungal infections without toxicity

Seaweed symbionts reveal treasure trove of potential drug compounds

Fighting invisible foes: How cryptic fungal pathogens threaten human health and food security

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

Can herbal remedies, spices, and dietary fibers offer effective treatment options for children with irritable bowel syndrome (IBS)?

Could seaweeds be the superfood and medicine of the future?

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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