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Research findings could lead to development of novel therapeutic approaches against viral infections

Research findings could lead to development of novel therapeutic approaches against viral infections

Life is a question of balance, and the body is no exception. Expression levels of certain proteins can affect the immune system's ability to neutralize a virus. [More]
Study shows promising results for treating lymphoma patients with immune cell therapy

Study shows promising results for treating lymphoma patients with immune cell therapy

Lymphoma is the most common blood cancer. The disease occurs when immune cells called lymphocytes multiply uncontrollably. Cancerous lymphocytes can travel throughout the body and form lymph node tumors. [More]
Targeting Legumain could be promising strategy for treatment of cancer

Targeting Legumain could be promising strategy for treatment of cancer

Legumain (LGMN), or asparaginyl endopeptidase, is a newly identified lysosomal cysteine protease. [More]
Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity. [More]
Clinical Genomics introduces new blood-based test for CRC recurrence monitoring

Clinical Genomics introduces new blood-based test for CRC recurrence monitoring

Clinical Genomics, a private company developing evidence-based diagnostic tools for colorectal cancer, today announced the launch of Colvera, a blood-based test for colorectal cancer (CRC) recurrence monitoring. Colvera is the result of a decade of research, development and clinical validation in more than 4,000 patients. [More]
Dual treatment strategies lengthen lives of mice with skin cancer

Dual treatment strategies lengthen lives of mice with skin cancer

By combining two treatment strategies, both aimed at boosting the immune system's killer T cells, Johns Hopkins researchers report they lengthened the lives of mice with skin cancer more than by using either strategy on its own. [More]
Targeted alpha therapy shows promise in treatment of metastatic prostate cancer

Targeted alpha therapy shows promise in treatment of metastatic prostate cancer

Nearly three years of research have brought about remarkable results for the majority of 80 patients subjected to targeted alpha therapy of metastatic prostate cancer. [More]
Okayama University researchers identify link between plant complex type N-glycans and hay fever

Okayama University researchers identify link between plant complex type N-glycans and hay fever

Okayama University researchers identify plants expressing substantial amounts of a nitrogen-linked polysaccharide – plant complex type N-glycans – which is linked to allergic responses in mammals, and may provide useful study models for understanding hay fever. [More]
Study shows the use of Renishaw inVia™ microscope in prostate cancer detection

Study shows the use of Renishaw inVia™ microscope in prostate cancer detection

New research at the Guangdong Medical University suggests a laser-based approach could be the latest breakthrough in prostate cancer detection. The proposed non-invasive blood test uses a combination of two techniques: surface-enhanced Raman scattering (SERS) and a new mathematical analysis technique called support vector machine (SVM). [More]
Researchers develop new method to identify antigens for cancer treatment

Researchers develop new method to identify antigens for cancer treatment

New cancer therapies harness the immune system to fight tumors. One of the main principles behind these therapies is to find out precisely which molecules on cancer cells trigger an immune response. [More]
Genes that control immune system play key role in predisposition to HPV-related tumors

Genes that control immune system play key role in predisposition to HPV-related tumors

A number of genetic variants associated with susceptibility to oral cavity and pharyngeal cancer have been described in an international study published in the journal Nature Genetics. [More]
Combatting Antibiotic Resistance, the role of POC Diagnostics

Combatting Antibiotic Resistance, the role of POC Diagnostics

During the winter months, patients frequently present with respiratory symptoms like coughing, sneezing and fever that could be caused by one of several bacterial and viral infections including influenza, respiratory syncytial virus (RSV) or bacterial pneumonia. [More]
PITX2 methylation biomarker shows promise for predicting prostate cancer recurrence risk

PITX2 methylation biomarker shows promise for predicting prostate cancer recurrence risk

Prostate-specific antigen (PSA) and other biomarkers are essential tools for diagnosing and monitoring prostate cancer. [More]
NIH scientists unravel chain of events that lead to fatal outcomes in cerebral malaria

NIH scientists unravel chain of events that lead to fatal outcomes in cerebral malaria

Using state-of-the-art brain imaging technology, scientists at the National Institutes of Health filmed what happens in the brains of mice that developed cerebral malaria (CM). [More]
Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children's Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation. [More]
Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

New research demonstrates that a novel imaging agent can quickly and accurately detect metastasis of prostate cancer, even in areas where detection has previously been difficult. [More]
Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells. [More]
Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

An international group of researchers report success in mice of a method of using positron emission tomography scans to track, in real time, an antibody targeting a hormone receptor pathway specifically involved in prostate cancer. [More]
NTM lung infections

NTM lung infections

Nontuberculous mycobacteria are part of a group of bacteria called mycobacteria. The non-tuberculous mycobacteria are, as the name suggests, mycobacteria that are not tuberculosis. They're also not leprosy, but they are the other members of the bacteria group termed mycobacteria. [More]
Researchers uncover new clues that may help combat leukemia and other B cell cancers

Researchers uncover new clues that may help combat leukemia and other B cell cancers

When B lymphocytes (a type of white blood cell in the immune system geared for fighting diseases) turn cancerous, they become part of the problem, and need to be eliminated. [More]
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