Antipsychotic News and Research

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Antipsychotics are medicines used to treat the symptoms of mental disorders such as schizophrenia, depression, bipolar disorder (sometimes called manic-depressive illness), anxiety disorders, and attention deficit-hyperactivity disorder (ADHD). Sometimes medications are used with other treatments such as psychotherapy.

Research identifies characteristics linked with higher risk of sudden cardiac arrest in people with type 2 diabetes

New research being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 Oct) has identified a range of characteristics associated with a higher risk of sudden cardiac arrest in individuals with type 2 diabetes.

4 Oct 2023

New study reveals genetic overlap between schizophrenia and cardiovascular disease risk factors

New research finds that people with schizophrenia have a genetic propensity to smoking and a reduced genetic risk of obesity.

27 Sep 2023

One health wake-up call: London's river data highlights environmental perils

The largest-ever spatiotemporal monitoring of chemicals/contaminants of emerging concern (CECs) in London waterways.

26 Sep 2023

New study maps the spread of brain changes in psychosis

Psychoses like schizophrenia cost billions of dollars annually and derail the lives of people struggling with the disease.

20 Sep 2023

Antipsychotics are likely overprescribed among homebound patients with dementia, study shows

New research published in the Journal of the American Geriatrics Society indicates that antipsychotics are likely overprescribed and used inappropriately among patients with Alzheimer's disease and related dementias (ADRD) receiving home health care, and such use is linked to worse patient outcomes.

7 Sep 2023

FDA approved Rexulti to be the first antipsychotic for treating agitation in elderly patients with dementia

In trials, the antipsychotic drug brexpiprazole (Rexulti) failed to provide a clinically meaningful benefit and increased the risk of death. Yet the US Food and Drug Administration (FDA) has fast tracked its approval, making Rexulti the first antipsychotic for treating agitation in elderly patients with dementia.

18 Aug 2023

Antidepressants may help prevent bipolar depression relapse

Treatment with modern antidepressants may help prevent patients with bipolar disorder from relapsing into a depressive episode, according to an international clinical trial led by researchers at the University of British Columbia.

2 Aug 2023

People with dementia end up in emergency care 1.4 million times a year

A busy, crowded, confusing emergency room is not an ideal place for a person living with dementia.

24 Jul 2023

People with mental illness less likely to participate in cancer screening programs

A new study from Aarhus University shows that far too many people with psychological challenges do not accept offers of colorectal cancer screening.

29 Jun 2023

Autoantibodies against 'synaptic adhesion protein' can cause schizophrenia-related changes

Links have been reported between schizophrenia and proteins produced by the immune system that can act against one's own body, known as autoantibodies.

31 May 2023

Revolutionizing Schizophrenia Research with the Queensland Brain Institute

To commemorate World Schizophrenia Awareness Day, we spoke to three researchers from the Queensland Brain Institiute about their research, and why it is so important to raise awareness around Schizophrenia

23 May 2023

Black patients more likely to be chemically sedated at the EDs than their white counterparts

Black patients presenting at Emergency Departments (EDs) across the country with psychiatric complaints are 63 percent more likely to be chemically sedated than their white counterparts.

7 Apr 2023

Augmenting an antidepressant with aripiprazole may help some older adults with treatment-resistant depression

For older adults with clinical depression that has not responded to standard treatments, adding the drug aripiprazole (brand name Abilify) to an antidepressant they're already taking is more effective than switching from one antidepressant to another, according to a new multicenter study led by Washington University School of Medicine in St. Louis.

3 Mar 2023

Evidence of increased antipsychotic medication prescription rates among individuals with dementia during COVID-19 pandemic

Researchers investigated global trends in antipsychotic medication prescribing for individuals with dementia during the pre-coronavirus disease 2019 (COVID-19) pandemic period and the pandemic period.

30 Jan 2023

Brief roundup of research done by experts at UCLA Health

Below is a brief roundup of news and story ideas from the experts at UCLA Health.

21 Dec 2022

What is the impact of cholesterol on SARS-CoV-2 Spike protein-mediated membrane fusion?

Researchers assessed the impact of ceramide (CER) and cholesterol (CHOL) on membrane fusion mediated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

20 Dec 2022

'One size fits all' approach may not help address the needs of all young people with psychosis

Gold standard treatment plans for people with early psychosis have a patchy success rate, suggesting the need to develop more tailored approaches.

2 Dec 2022

Do SSRIs lower the risk of long COVID?

Researchers conducted a retrospective study to determine whether SSRIs with immunomodulatory and antiplatelet properties can decrease the risk of post-acute sequelae of COVID-19 (PASC).

15 Nov 2022

Researchers unravel how the brain chemical dopamine relates to schizophrenia

Researchers at the Lieber Institute for Brain Development (LIBD) believe they have solved a riddle that has challenged scientists for more than 70 years: how the brain chemical dopamine relates to schizophrenia, the often-devastating brain disorder characterized by delusional thinking, hallucinations and other forms of psychosis.

1 Nov 2022

People with schizophrenia are 2.5 times more likely to develop dementia

People with psychotic disorders such as schizophrenia are 2.5 times more likely than those without a psychotic disorder to eventually develop dementia, according to a review of evidence led by UCL researchers.

6 Oct 2022