Antipsychotic News and Research

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Antipsychotics are medicines used to treat the symptoms of mental disorders such as schizophrenia, depression, bipolar disorder (sometimes called manic-depressive illness), anxiety disorders, and attention deficit-hyperactivity disorder (ADHD). Sometimes medications are used with other treatments such as psychotherapy.

Antipsychotic drugs for dementia

Antipsychotic drugs are approved mainly for treating schizophrenia and bipolar disorder, but they are also used for many other purposes.

27 Jul 2007

New treatments for migraines and chronic headaches

Twelve percent of the population, three quarters of them women, suffer at least occasionally from migraines and about 5 percent from chronic headaches.

20 Jun 2007

Antipsychotic drugs used to treat dementia shorten life

A new Canadian study by a geriatric medicine specialist has found that the antipsychotic drugs used to treat some of the disruptive behaviours of older adults with dementia may shorten the patient's life.

5 Jun 2007

Common antipsychotic drug for methamphetamine overdose may damage brain cells

A common antipsychotic drug used in emergency rooms to treat methamphetamine overdose damages nerve cells in an area of the brain known to regulate movement, a new study shows.

30 May 2007

Study of Aripiprazole in adolescents with schizophrenia

In a six-week study in adolescents (13-17 years old) with schizophrenia, the Otsuka Pharmaceutical Co., Ltd. and Bristol-Myers Squibb Company atypical antipsychotic aripiprazole demonstrated significant improvement compared to placebo on the primary efficacy endpoint, Positive and Negative Syndrome Scale (PANSS) Total Score.

24 May 2007

Clinical study results on bifeprunox for schizophrenia

Solvay Pharmaceuticals, Inc., Wyeth Pharmaceuticals and Lundbeck A/S presented clinical study results on bifeprunox, an investigational treatment for adult patients diagnosed with schizophrenia, at the 2007 annual meeting of the American Psychiatric Association.

24 May 2007

Lupin receives FDA approval for Ziprasidone Hydrochloride capsules

Lupin Pharmaceuticals has announced that on May 16, 2007 it received tentative approval from the US FDA for its Abbreviated New Drug Application (ANDA) for Ziprasidone Hydrochloride Capsules 20mg, 40mg, 60mg and 80mg.

24 May 2007

Iloperidone shows promise for Akathisia

According to study results presented at the 2007 American Psychiatric Association annual meeting, iloperidone, an investigational atypical antipsychotic, was shown to have a favorable akathisia profile.

24 May 2007

Efficacy and safety of Aripiprazole as adjunctive therapy in major depressive disorder

In adults with major depressive disorder, adding aripiprazole to antidepressant therapy (ADT) resulted in significant improvement in the primary endpoint, the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score.

24 May 2007

Chemical maps hint at drug's effects on schizophrenia

Antipsychotic drugs do most of their work in the brain, but they also leave behind in the bloodstream a trail of hundreds of chemicals that may be used in the future to direct better treatment for schizophrenia and other psychiatric conditions, say Duke University Medical Center researchers.

16 May 2007

Bipolar all too often misdiagnosed

According to researchers from the National Institute of Mental Health (NIMH) there are twice as many Americans with bipolar disorder as previously thought, and many are untreated.

9 May 2007

Bipolar disorder may be more accurately characterized as a spectrum disorder

A new study supports earlier estimates of the prevalence of bipolar disorder in the U.S. population, and suggests the illness may be more accurately characterized as a spectrum disorder.

8 May 2007

Gene malfunctions cause schizophrenia, depression symptoms in mice

Researchers have demonstrated for the first time that malfunction of a gene that had been associated with schizophrenia and depression does indeed cause symptoms of those disorders.

4 May 2007

New compounds show potential for cognitive disorders

UC Irvine researchers have identified a new class of compounds that could be used for drugs to treat cognitive disorders that accompany schizophrenia, Alzheimer's disease and ADHD, according to an article published today in the online version of the Proceedings of the National Academy of Sciences.

2 May 2007

FDA approves INVEGA treatment for schizophrenia

The U.S. Food and Drug Administration (FDA) has approved INVEGA (paliperidone) Extended-Release Tablets, a new once-daily, atypical antipsychotic, for the long-term maintenance treatment of schizophrenia.

30 Apr 2007

Report identifies schizophrenia patients likely to receive depot medication

A report in the April 2007 issue of Psychiatric Services has identified a unique subgroup of schizophrenia patients in the United States who tend to receive depot antipsychotic medications.

26 Apr 2007

Psychotherapeutic drug spending surges

Spending on prescription drugs to treat depression, anxiety, pain, schizophrenia and other conditions climbed from $7.9 billion in 1997 to $20 billion in 2004 - over a 150 percent increase, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

25 Apr 2007