Aortic Stenosis News and Research

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Webcast on the treatment of cardiovascular diseases

On September 24th at 7:00pm EDT, Dr. Holly Andersen, Director of Education and Outreach at the Ronald O. Perelman Heart Institute at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, will host a live webcast exploring the advances and innovations in the treatment of cardiovascular disease. The air live on ORLive.com from the Hospital's new Ronald O. Perelman Heart Institute.

25 Sep 2009

Medtronic's transcatheter valves to be presented at TCT 2009

With the promise of percutaneous treatments for patients with diseased heart valves growing, Medtronic, Inc., announced today that more presentations than ever before – at least 25 – on the company’s portfolio of unique transcatheter valves will be presented at Transcatheter Cardiovascular Therapeutics (TCT) 2009, the world’s premier annual meeting for interventional cardiologists.

23 Sep 2009

Edwards Lifesciences updates on its SAPIEN valve clinical programs

Edwards Lifesciences Corporation (NYSE: EW), the world leader in the science of heart valves, today announced new clinical data demonstrating 100 percent freedom from structural deterioration of the Edwards SAPIEN valve at 18 months, as well as positive midterm patient outcomes resulting from the application of learnings from earlier clinical programs.

22 Sep 2009

Transcatheter valve implantation is an effective treatment for patients with aortic stenosis

Research presented at the 21st annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium, sponsored by the Cardiovascular Research Foundation (CRF), demonstrated an "exceptionally low" rate of complications one year after implantation of transcatheter aortic valve prostheses.

22 Sep 2009

New procedure for transapical valve replacement minimizes trauma and blood loss

Edwards Lifesciences Corporation (NYSE: EW), the world leader in the science of heart valves, announced today the first successful clinical use of its new lower-profile Ascendra 2 transapical delivery system, designed to benefit both patients and physicians by minimizing trauma and blood loss, and facilitating transcatheter heart valve delivery and deployment.

9 Sep 2009

Edwards Lifesciences completes patient enrollment for transcatheter heart valve study

Edwards Lifesciences Corporation (NYSE: EW), the world leader in the science of heart valves, today announced completion of enrollment in its 1,040-patient randomized controlled Investigational Device Exemption (IDE) study of the Edwards SAPIEN transcatheter heart valve.

1 Sep 2009

Ochsner Medical Center selected to participate as an FDA investigative site in the PARTNER clinical trial

On Tuesday, August 11, 2009, an 82-year old New Orleans resident with severe aortic stenosis successfully had a heart valve replaced at Ochsner Medical Center using the same technique as angioplasty, a far cry from the traditional open heart procedure. Patients who are considered high-risk or non-operable for conventional open heart valve surgery now have a potential new research option available regionally only through The John Ochsner Heart & Vascular Institute.

28 Aug 2009

TCT Featured Clinical Trials to be presented on September 24 in San Francisco

A series of Featured Clinical Trials will be presented at Transcatheter Cardiovascular Therapeutics (TCT), in addition to late-breaking clinical trials. These featured clinical trials represent groundbreaking research and will yield data and insight that will further the field of interventional cardiology.

21 Aug 2009

Valve implantation on the beating heart

Transcatheter valve implantation is a newly developed technique for the curative treatment of high-grade aortic stenosis.

21 Apr 2009

Results from the Simvastatin and Ezetimibe in aortic stenosis study

The SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) study has investigated the effects of intensive cholesterol lowering with the combination of simvastatin (40 mg daily) and ezetimibe (10 mg daily) in patients with aortic stenosis.

2 Sep 2008

Transcatheter aortic valve replacement - a new frontier in cardiovascular medicine

Replacing heart valves without the substantial trauma of opening the chest and the heart were little known concepts until the groundbreaking pulmonary and aortic transcatheter valve replacements performed during 2000 and 2002, respectively by Philipp Bonhoeffer and Alain Cribier.

1 Sep 2008

Transapical aortic valve implantation

Transapical aortic valve implantation (TA-AVI) is a new therapeutic strategy, which has been implemented successfully into clinical practice in several hundred patients suffering symptomatic aortic stenosis and an increase perioperative risk during the past two years. The Edwards SAPIEN prosthesis has been used.

1 Sep 2008

Exercise testing to predict mitral regurgitation

In as many as one in five people over age 55, when the heart contracts to send blood around the body, some degree of backward leakage occurs across the mitral valve, a condition known as mitral regurgitation (MR).

12 Dec 2007

Exercise testing may help predict seriousness of mitral regurgitation

12 Dec 2007

First European guidelines on the management of valvular heart disease

Today valve disease still represents an important health problem; valve patients are getting older and older with more and more comorbities, which contribute to increased operative risk and render the decision-making process more difficult.

3 Sep 2007

Morgan Stanley Children's Hospital performs transcatheter pulmonary valve replacement

A breakthrough new procedure may improve quality of life for children and adults with a common type of congenital heart defect that interferes with the body's ability to oxygenate blood through the lungs.

24 Aug 2007

Catheter-based aortic valve replacement is set to take off

Twenty years ago, few interventional cardiologists could have imagined that during their professional careers it would be possible to replace a diseased aortic valve using catheter-based techniques, rather than open-chest surgery.

11 May 2007

Antibiotics before dental procedures may do more harm than good

Taking a precautionary antibiotic before a trip to the dentist isn't necessary for most people, and in fact, might create more harm than good, according to updated recommendations from the American Heart Association.

20 Apr 2007

Fewer heart patients need antibiotics before dental procedures to prevent infective endocarditis

Based on a review of new and existing scientific evidence, most dental patients with heart disease do not need antibiotics before dental procedures to prevent infective endocarditis (IE), a rare, but life-threatening heart infection.

20 Apr 2007

Statins slow the progression of aortic valve stenosis

The trial provides the first prospective clinical evidence that aortic valves have an active biology that can be targeted with medical therapy and contradicts research published in 2005 in the New England Journal of Medicine, which concluded statins did not halt the progression of aortic stenosis.

30 Jan 2007