Apolipoprotein News and Research

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Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

Researchers investigate the role of neurotrophic factors on the cognitive performance of Alzheimer’s disease patients carrying the apolipoprotein E 4 gene.

1 Mar 2023

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Researchers characterize the effects of neuronal apolipoprotein E4 on Alzheimer’s disease-associated pathology.

23 Feb 2023

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

Can carbohydrate be reduced too low for weight loss, and glycemic control?

A new review in the Journal of Clinical Lipidology aimed to describe the definitions of carbohydrate-restricted dietary patterns, the potential benefits related to cardiometabolic risk factors, and whether healthcare professionals should consider it for glycemic management and weight loss.

9 Feb 2023

Study demonstrates intrahost MPXV variation within a single lesion

Researchers reported on the clinical and molecular characteristics of MPXV infections in Finland.

31 Jan 2023

Study of older adults in China finds link between a healthy lifestyle and slower memory decline

A healthy lifestyle, in particular a healthy diet, is associated with slower memory decline, finds a decade-long study of older adults in China, published today in The BMJ.

26 Jan 2023

Mpox has been silently circulating in non-mpox-endemic nations for 20 years, according to new study

Researchers described the evolution of the mpox virus (MPXV) before the 2022 outbreak.

19 Jan 2023

How does the brain change with age?

Researchers discussed cellular hallmarks of brain aging and therapeutic interventions to rejuvenate cognitive brain functions.

19 Jan 2023

New research draws attention to the effects of deep meditation on gut health

Researchers investigated the effects of long-term traditional Tibetan Buddhist meditation on the gut microbiome's structural characteristics. Additionally, they screened microbes in the gut microbiota for insights into their biochemical indices and functionality.

19 Jan 2023

Long-term deep meditation may help to regulate the gut microbiome for better health

Regular deep meditation, practiced for several years, may help to regulate the gut microbiome and potentially lower the risks of physical and mental ill health, finds a small comparative study published in the open access journal General Psychiatry.

17 Jan 2023

Walking pace and handgrip strength can indicate dementia risk

The current study, published in the journal Alzheimer's Research & Therapy, drew data on almost 496,000 participants from the UK Biobank Study. None had symptoms or a diagnosis of dementia at the start of the study.

15 Jan 2023

Genomic analysis of mpox virus genomes reveal multiple lineages with human-to-human transmissibility

Researchers from Nigeria and the United Kingdom (U.K.) analyzed mpox virus genomes and found that divergent lineages of the mpox virus exhibiting human-to-human transmission existed in the Nigerian population before the 2022 spread of the virus outside of the endemic regions.

10 Jan 2023

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers."

3 Jan 2023

Moderate alcohol intake may affect lipoprotein metabolism

A recent Nutrients journal study evaluated the impact of 1-2 drinks of alcohol per day on cardiovascular biomarkers in the cross-over intervention, prospective, and assessor-blinded trial called the Metabolic Imprints of Alcoholic Beverages (MetAl).

30 Nov 2022

Honey improves key measures of health, including blood sugar and cholesterol levels

Researchers look to better understand the impact of honey on mitigating certain cardiometabolic risk factors.

20 Nov 2022

Metabolomic study of genetic regulation of biochemical individuality

Researchers systematically investigated the genetic makeup of nearly 20,000 women and men in terms of >900 metabolites.

15 Nov 2022

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Researchers reviewed research advancements showing the significant role both innate and adaptive immune systems play in the pathological course of Alzheimer’s disease.

10 Nov 2022

Low meal frequency is suggested to decrease Alzheimer’s disease risk

Researchers evaluated the associations between low meal frequency (LMF) and Alzheimer’s disease (AD).

24 Oct 2022

Study explores the effect of COVID-19 on platelet function

A new study posted in the pre-print server bioRxiv* aimed to analyze the impact of COVID-19 on platelet proteome and relate the functional responses of platelets and the formation of platelet-neutrophil aggregate in hospitalized COVID-19 patients.

17 Oct 2022

USF researchers test a protein that shows potential as novel therapeutic for ALS patients

Researchers at the USF Health Morsani College of Medicine, located at the University of South Florida, successfully tested a protein that has the potential to aid in the development of a protein-based therapy for patients with ALS, a progressive nervous system disease, also known as Lou Gehrig's disease, that affects nerve cells in the brain and spinal cord.

7 Oct 2022

Apolipoprotein News and Research

Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

Apolipoprotein E4 promotes the development of Alzheimer’s disease

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Can carbohydrate be reduced too low for weight loss, and glycemic control?

Study demonstrates intrahost MPXV variation within a single lesion

Study of older adults in China finds link between a healthy lifestyle and slower memory decline

Mpox has been silently circulating in non-mpox-endemic nations for 20 years, according to new study

How does the brain change with age?

New research draws attention to the effects of deep meditation on gut health

Long-term deep meditation may help to regulate the gut microbiome for better health

Walking pace and handgrip strength can indicate dementia risk

Genomic analysis of mpox virus genomes reveal multiple lineages with human-to-human transmissibility

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

Moderate alcohol intake may affect lipoprotein metabolism

Honey improves key measures of health, including blood sugar and cholesterol levels

Metabolomic study of genetic regulation of biochemical individuality

The roles of innate and adaptive immunity in Alzheimer’s disease development and progression

Low meal frequency is suggested to decrease Alzheimer’s disease risk

Study explores the effect of COVID-19 on platelet function

USF researchers test a protein that shows potential as novel therapeutic for ALS patients

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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