Atherosclerosis News and Research RSS Feed - Atherosclerosis News and Research

Atherosclerosis is the progressive buildup of plaque - the fatty deposits and other cells - in the inner walls of the arteries. The condition is a consequence of elevated cholesterol and for many it's a silent disease, with no visible signs or symptoms. The disease can begin in early adulthood and continues to progress for the rest of a person's life. Despite the serious nature of atherosclerosis, many people do not understand how it develops and progresses.
Obese boys are at 6 fold increased risk of hypertension compared to normal weight boys

Obese boys are at 6 fold increased risk of hypertension compared to normal weight boys

Obese youths have a nearly six fold risk of hypertension, according to research in more than 22 000 young people from the PEP Family Heart Study presented at ESC Congress today by Professor Peter Schwandt from Germany. [More]
Darapladib drug fails to reduce risk of recurrent major coronary events

Darapladib drug fails to reduce risk of recurrent major coronary events

In patients who experienced an acute coronary syndrome (ACS) event (such as heart attack or unstable angina), use of the drug darapladib to inhibit the enzyme lipoprotein-associated phospholipase A2 (believed to play a role in the development of atherosclerosis) did not reduce the risk of recurrent major coronary events, according to a study published by JAMA. [More]
Combination of moderate wine drinking plus regular exercise protects against CVD

Combination of moderate wine drinking plus regular exercise protects against CVD

Wine only protects against cardiovascular disease (CVD) in people who exercise, according to results from the In Vino Veritas (IVV) study presented at ESC Congress today by Professor Milos Taborsky from the Czech Republic. [More]
Study: Resistant hypertension increases risk of stroke in female and elderly patients

Study: Resistant hypertension increases risk of stroke in female and elderly patients

Resistant hypertension increases the risk of stroke by 35% in women and 20% in elderly Taiwanese patients, according to research presented at ESC Congress today by Dr Kuo-Yang Wang from Taiwan. [More]
New journal on cardiovascular pharmacotherapy from ESC

New journal on cardiovascular pharmacotherapy from ESC

A new ESC journal on cardiovascular pharmacotherapy is launched today at ESC Congress by the ESC and Oxford University Press. [More]
Janssen, Bayer announce expansion of EXPLORER global cardiovascular research program for XARELTO

Janssen, Bayer announce expansion of EXPLORER global cardiovascular research program for XARELTO

Janssen Research & Development, LLC and its development partner, Bayer HealthCare, announced today the expansion of the EXPLORER global cardiovascular research program for XARELTO (rivaroxaban) to include additional high-risk patient populations. [More]
Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Amgen today announced the submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration for evolocumab seeking approval for the treatment of high cholesterol. [More]
New UCLA study finds that oxidized lipids may also contribute to pulmonary hypertension

New UCLA study finds that oxidized lipids may also contribute to pulmonary hypertension

Oxidized lipids are known to play a key role in inflaming blood vessels and hardening arteries, which causes diseases like atherosclerosis. A new study at UCLA demonstrates that they may also contribute to pulmonary hypertension, a serious lung disease that narrows the small blood vessels in the lungs. [More]
People with cognitive impairment are more likely to have stroke

People with cognitive impairment are more likely to have stroke

People with cognitive impairment are significantly more likely to have a stroke, with a 39% increased risk, than people with normal cognitive function, according to a new study published in CMAJ (Canadian Medical Association Journal). [More]
Calcium buildup in coronary arteries of chronic kidney disease patients indicates heart disease risk

Calcium buildup in coronary arteries of chronic kidney disease patients indicates heart disease risk

Calcium buildup in the coronary arteries of chronic kidney disease patients may be a strong indicator of heart disease risk, according to a new study in the Journal of the American Society of Nephrology (JASN). [More]
Study could pave way for preventing brain and cardiac ischemia induced by atherosclerosis

Study could pave way for preventing brain and cardiac ischemia induced by atherosclerosis

A recent Finnish study could pave the way for preventing brain and cardiac ischemia induced by atherosclerosis. Finnish researchers have found that the low-expression variant of fatty acid-binding protein 4 (FABP4), which is particularly common among Finns, reduces the risk of heart attack and stroke. [More]
NTU research could lead to better treatment options for children suffering from leukaemia

NTU research could lead to better treatment options for children suffering from leukaemia

A research team led by Nanyang Technological University scientists have made a key finding which is expected to open up improved treatment possibilities for children suffering from leukaemia. [More]
Findings open up improved treatment possibilities for children suffering from leukaemia

Findings open up improved treatment possibilities for children suffering from leukaemia

A research team led by Nanyang Technological University (NTU) scientists have made a key finding which is expected to open up improved treatment possibilities for children suffering from leukaemia. [More]
Researchers make significant step forward in understanding mechanisms that cause leukaemia

Researchers make significant step forward in understanding mechanisms that cause leukaemia

Scientists from Queen Mary University of London have discovered mutations in genes that lead to childhood leukaemia of the acute lymphoblastic type - the most common childhood cancer in the world. [More]
Scientists identify long-overlooked function of vascular smooth muscle cells in atherosclerosis

Scientists identify long-overlooked function of vascular smooth muscle cells in atherosclerosis

Scientists at the Interfaculty Institute of Biochemistry (IFIB) have collaborated with colleagues from the Department of Pharmacy and the Department of Dermatology of the University of Tübingen to identify a long-overlooked function of vascular smooth muscle cells in atherosclerosis. [More]
Midlife hypertension link to later-life cognitive decline strengthened

Midlife hypertension link to later-life cognitive decline strengthened

Analysis of the Atherosclerosis Risk in Communities study cohort supports an association between elevated blood pressure in midlife and increased cognitive decline in older age. [More]
Scientists discover gene that plays vital role in blood vessel formation

Scientists discover gene that plays vital role in blood vessel formation

Scientists from the University of Leeds have discovered a gene that plays a vital role in blood vessel formation, research which adds to our knowledge of how early life develops. [More]
CardioNova initiates Phase 1b clinical trial with AtheroNova's AHRO-001

CardioNova initiates Phase 1b clinical trial with AtheroNova's AHRO-001

AtheroNova Inc., a biotech company focused on the research and development of compounds to safely regress atherosclerotic plaque and improve lipid profiles in humans, today announces that its partner, CardioNova, has accomplished first dosing of subjects for its Phase 1b clinical trial with AtheroNova's lead compound, AHRO-001. [More]
Diet rich in soy may help feminine hearts, but timing matters

Diet rich in soy may help feminine hearts, but timing matters

A diet rich in soy may help feminine hearts, but timing matters, finds a new study published online today in Menopause, the journal of The North American Menopause Society. [More]
UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

Millions of people in the United States have a circulatory problem of the legs called peripheral vascular disease. It can be painful and may even require surgery in serious cases. This disease can lead to severe skeletal muscle wasting and, in turn, limb amputation. [More]