Atomic Force Microscopy News and Research

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Atomic force microscopy is a type of scanning probe microscopy used to image the surface of a substance, but at an atomic level. It can map the surface structure of different substances to understand how different structures interact with each other. This is done using a cantilever, which is similar to a vinyl record needle.

The road to achieving single molecular spectroscopy using nanoIR

In this interview, Francesco Simone Ruggeri from the University of Cambridge talks to News-Medical Life Sciences about their research into biomolecules and the methods that are helping to achieve spectra at the single-molecule scale.

From Bruker Nano Surfaces and Metrology 30 Oct 2020

Study links SARS-CoV-2 seasonality to increased spread at lower temperatures

In a recent paper available on the bioRxiv preprint server, US researchers show that individual particles of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) undergo structural destabilization at relatively mild but elevated temperatures – strengthening the case for coronavirus disease (COVID-19) resurgence in the winter.

15 Oct 2020

Scientists produce biodegradable nanocoating with antimicrobial and anti-reflective properties

Scientists from Russia and Switzerland have probed into nanostructures covering the corneas of the eyes of small fruit flies. Investigating them the team learned how to produce the safe biodegradable nanocoating with antimicrobial, anti-reflective, and self-cleaning properties in a cost-effective and eco-friendly way.

14 Oct 2020

Researchers try and pop SARS-CoV-2 with an AFM tip - virion surprisingly resilient

Researchers at Semmelweis University and the National Public Health Center in Hungary have conducted an imaging study showing that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent responsible for coronavirus disease 2019 (COVID-19), is a highly dynamic and resilient virus

20 Sep 2020

Study identifies a gene's previously unknown role in fertility

A new study from Washington University School of Medicine in St. Louis identifies a specific gene's previously unknown role in fertility.

31 Aug 2020

Researchers reveal how bacteria adhere to cellulose fibers in the gut

Researchers have revealed a new molecular mechanism by which bacteria adhere to cellulose fibers in the human gut. Thanks to two different binding modes, they can withstand the shear forces in the body.

28 Aug 2020

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses.

17 Aug 2020

High-speed atomic force microscopy reveals diverse amyloid structures and dynamics

In the human body, proteins sometimes occur in fibrillar aggregates called amyloids. Although certain amyloids are known to have a biological function, amyloid formation is often associated with pathologies, including Alzheimer's and Parkinson's diseases.

3 Aug 2020

Atomic force microscopy reveals nanoscale effects of beverages on tooth enamel

KAIST researchers used atomic force microscopy to quantitatively evaluate how acidic and sugary drinks affect human tooth enamel at the nanoscale level.

22 Jul 2020

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Synchrotron InfraRed Nanospectroscopy has been used for the first time to measure biomolecular changes induced by a drug (amiodarone) within human cells (macrophages) and localized at 100 nanometre scale, i.e. two orders of magnitude smaller than the IR wavelength used as probe.

17 Jul 2020

Real-time tracking of protein filaments in the nuclear pore complex

In human cells, the nucleus is enclosed by a structure called the nuclear pore complex (NPC). It acts as a 'gatekeeper' controlling the transport of molecules between the nucleus and the surrounding cytoplasm (the protein-containing solution in the inside of a cell).

6 Jul 2020

Cellular mechanophenotyping may provide more comprehensive view of the tumor

Our ability to predict who will get cancer, how a patient will respond to treatment, or if a patient will relapse is still quite limited. Despite advances in the detection of genetic mutations and the establishment of risk factors, such as age and genetic variants, it remains a great scientific and medical challenge.

9 Jun 2020

Atomic Force Microscopy News and Research

Further Reading

The road to achieving single molecular spectroscopy using nanoIR

Study links SARS-CoV-2 seasonality to increased spread at lower temperatures

Scientists produce biodegradable nanocoating with antimicrobial and anti-reflective properties

Researchers try and pop SARS-CoV-2 with an AFM tip - virion surprisingly resilient

Study identifies a gene's previously unknown role in fertility

Researchers reveal how bacteria adhere to cellulose fibers in the gut

New technique enables real-time observation of influenza A hemagglutinin during viral entry

High-speed atomic force microscopy reveals diverse amyloid structures and dynamics

Atomic force microscopy reveals nanoscale effects of beverages on tooth enamel

Novel nanospectroscopy measures biomolecular changes induced by drugs in human cells

Real-time tracking of protein filaments in the nuclear pore complex

Cellular mechanophenotyping may provide more comprehensive view of the tumor

New insight on mechanism of prions brings hope for treating neurodegenerative diseases

NYUAD researchers develop new microfluidic platform to perform cancer liquid biopsies

Investigating the nanoscale adhesion mechanisms between polymeric biomaterials and biological samples

Research shows how physical cues drive cell migration, cancer metastasis, and treatment

Molecular-level understanding of drug interactions could pave way for better malaria treatments

Single-particle method helps determine isoelectric point of viruses

Researchers reveal how antibodies assemble to form a circle for defensive attack

Virginia Tech professor wins NSF grant to study biofilm formation in bacteria

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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