Avascular Necrosis News and Research

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Women with metastatic breast cancer can receive bisphosphonates less frequently and safely

Women with metastatic breast cancer to the bone may be able to receive bisphosphonates, the bone-targeting class of drugs like zoledronic acid, less often after the first year of monthly administration.

31 May 2014

Drugs used to treat osteoporosis appear to prevent cell membrane repair

A class of drugs widely used to treat osteoporosis appears to impede a cell's ability to repair a protective outer membrane that helps determine what enters and exits, researchers report.

15 Apr 2014

$New MRI can show detailed image following fracture repair without distortion by metal surgical screws$

New MRI can show detailed image following fracture repair without distortion by metal surgical screws

People who sustain the most common type of hip fracture, known as a femoral neck fracture, are at increased risk of complications. A special type of MRI developed at Hospital for Special Surgery in collaboration with GE Healthcare can show a detailed image following fracture repair, without the distortion caused by metal surgical screws that are problematic in standard MRIs.

12 Mar 2014

Women are most likely to experience serious pain following knee replacement than men

Middle-aged women with rheumatoid arthritis or arthritis resulting from an injury are among the patients most likely to experience serious pain following a knee replacement, researchers from Hospital for Special Surgery (HSS) in New York have found.

12 Mar 2014

Nanodiamond-drug embedded in contact lenses shows great promise for glaucoma treatment

By 2020, nearly 80 million people are expected to have glaucoma, a disorder of the eye that, if left untreated, can damage the optic nerve and eventually lead to blindness.

19 Feb 2014

$Risedronate may help prevent new vertebral fractures when taken with calcium and vitamin D$

Risedronate may help prevent new vertebral fractures when taken with calcium and vitamin D

A recent prospective, randomized, placebo-controlled clinical trial reports that calcium and vitamin D supplementation improves bone density in a group of male veterans with epilepsy who were treated chronically with antiepileptic drugs.

8 Nov 2013

Vitamin D and calcium improves bone density in male veterans treated with AEDs

8 Nov 2013

MRSA musculoskeletal infections increasing among children

Pediatric musculoskeletal Staphylococcus aureus bacterial infections have been evolving over the past decade, with more children diagnosed with the more virulent, methicillin-resistant Staphylococcus aureus today than 10 years ago.

28 Oct 2013

Nanodiamonds could be used to promote bone growth and durability of dental implants

UCLA researchers have discovered that diamonds on a much, much smaller scale than those used in jewelry could be used to promote bone growth and the durability of dental implants.

19 Sep 2013

Weekend reading: Doctors who decide, death desires, and decisions

On the last week of April earlier this year, a small committee of doctors met quietly in a midsized ballroom at the Renaissance Hotel in Chicago. There was an anesthesiologist, an ophthalmologist, a radiologist, and so on-;thirty-one in all, each representing their own medical specialty society, each a heavy hitter in his or her own field.

12 Jul 2013

Study shows patients with avascular necrosis have turned to stem cell therapy for aid

Stem cells have long been touted as the next big thing. Well just maybe, it is here. According to Dr. Dennis Lox, some patients with a disorder of the bone called avascular necrosis (AVN), have turned to stem cell therapy for aid.

15 Jun 2013

Xgeva receives FDA approval for treating giant cell tumor of the bone

The U.S. Food and Drug Administration today expanded the approved use of Xgeva (denosumab) to treat adults and some adolescents with giant cell tumor of the bone, a rare and usually non-cancerous tumor.

14 Jun 2013

Medication use and doctor visits drive up jaw necrosis-related costs

Long-term medication use and follow-up visits are the main drivers affecting costs associated with cancer-related bisphosphonate-associated osteonecrosis of the jaw, report researchers in Oral Diseases.

8 Mar 2013

Perthes’ disease link to congenital disorders revealed

Researchers have linked Perthes' disease with several congenital conditions, pointing to intra-uterine factors behind the development of the disease.

14 Dec 2012

Caltech-led team discovers enzyme responsible for neural crest cell development

During the early developmental stages of vertebrates-animals that have a backbone and spinal column, including humans-cells undergo extensive rearrangements, and some cells migrate over large distances to populate particular areas and assume novel roles as differentiated cell types.

3 Nov 2012

Bisphosphonates increase risk for bone disease after tooth extraction

The risk for developing osteonecrosis of the jaw after a tooth extraction is significantly higher among patients who receive bisphosphonates than those who do not, suggest study findings.

23 Oct 2012

New JEBDP series provides updates on evidence-based care in periodontics and implant dentistry

What's the latest, research-supported best practice in periodontal care and implant dentistry? Dental specialists and generalists alike can read about it in the first of a new series from The Journal of Evidence-Based Dental Practice (JEBDP), the foremost publication of information about evidence-based dental practice, published by Elsevier.

4 Oct 2012

Age at onset influences juvenile dermatomyositis course

Children diagnosed with juvenile dermatomyositis at age 3 years or earlier have milder symptoms than patients with later onset, research suggests.

24 Sep 2012

$Simple interventions boost vertebral fracture osteoporosis care$

Simple interventions boost vertebral fracture osteoporosis care

Use of osteoporosis investigation and treatment is significantly increased in older patients with asymptomatic vertebral fracture by use of physician- and patient-targeted interventions, Canadian research suggests.

7 Sep 2012

Radiotherapy redundant in low-risk Hodgkin lymphoma treatment

Children with low-risk Hodgkin lymphoma who respond well to chemotherapy may not require additional radiotherapy, suggest study results.

10 Jul 2012