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Elusys presents positive results of obiltoxaximab for treating inhalational anthrax, post-exposure prophylaxis

Elusys Therapeutics, Inc. (Elusys), a biopharmaceutical company developing antibody therapies to treat infectious disease, presented data demonstrating that obiltoxaximab (ETI-204) demonstrated a statistically significant survival benefit across a range of disease severity in animal model studies assessing treatment of inhalational anthrax, as well as effectiveness in post-exposure prophylaxis.

13 Feb 2015

Biotech experts to establish ethical guidelines in cellular biotechnology at BEINGS 2015

In May 2015 Atlanta will host Biotechnology and the Ethical Imagination: A Global Summit (BEINGS), an international summit drawing together the world's thought leaders on the highly debated issues of cellular biotechnology.

13 Feb 2015

RAB3GAP complex plays important role in autophagy

Neurodegenerative disorders such as Alzheimer's disease are typically characterized by protein deposits in the brain. These are comprised of defective, insoluble proteins which no longer fulfill their function and which cells are unable to break down. The work group headed by Professor Christian Behl of the Institute of Pathobiochemistry of the University Medical Center of Johannes Gutenberg University Mainz has determined the RAB3GAP complex as a novel factor that influences the efficient degradation of proteins.

12 Feb 2015

Oral pathogen protects different tumor cells from being killed by immune cells

Bacteria that are commonly found in the mouth are often abundant in patients with colon cancer, but the potential role these microbes play in tumor development has not been clear. A study published by Cell Press February 18th in the journal Immunity reveals that the oral pathogen Fusobacterium nucleatum protects a variety of tumor cells from being killed by immune cells.

12 Feb 2015

Diabetes medication can help white blood cells fight bacterial infections

Pioglitazone, a medication approved for treatment of type 2 diabetes, can help bypass genetic defects in chronic granulomatous disease to help white blood cells fight bacterial infections, according to researchers at National Jewish Health.

12 Feb 2015

Health Canada: Parents advised not to feed honey to infants less than one year old

In Canada, honey is the only food which has been linked to infant botulism – a rare but serious illness that is caused by ingesting the bacterium C. botulinum.

12 Feb 2015

Standard cleaning procedures in retail delis may not eradicate Listeria pathogen, study shows

Purdue University research shows that standard cleaning procedures in retail delis may not eradicate Listeria monocytogenes bacteria, which can cause a potentially fatal disease in people with vulnerable immune systems.

11 Feb 2015

OSU researchers discover impact of antibiotics on microorganisms that live in animal's gut

Researchers at Oregon State University have discovered that antibiotics have an impact on the microorganisms that live in an animal's gut that's more broad and complex than previously known.

11 Feb 2015

Single genomic change can make beneficial bacteria into pathogenic bacteria

We, as most animals, host many different beneficial bacteria. Being beneficial to the host often pays off for the bacteria, as success of the host determines the survival and spread of the microbe. But if bacteria grow too much they may become deadly.

11 Feb 2015

Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, today announced positive topline safety and tolerability results from a Phase 1b clinical trial of SYN-004, the Company's investigational oral beta-lactamase enzyme designed to protect the microbiome and prevent Clostridium difficile (C. difficile) infection, antibiotic-associated diarrhea and secondary antibiotic-resistant infections in patients receiving intravenous (IV) beta-lactam antibiotic therapy.

10 Feb 2015

University of Tokyo researchers reveal how TLR9 binds to pathogen DNA

University of Tokyo researchers have elucidated how Toll-like receptor 9 (TLR9) binds to pathogen DNA, activating the innate immune system. This discovery is vital for the design of new antiviral, antibacterial, allergy and other drugs targeting TLR9.

10 Feb 2015

IU researchers awarded NIH grant to develop new weapon to fight against antibiotic-resistant bacteria

The alarming increase of antibiotic-resistant bacteria poses health and economic threats worldwide, with more than 2 million Americans infected by the bacteria each year. Now, a team of Indiana University chemists and biologists has been awarded a major grant to develop and use a chemical tagging method to better understand how bacteria build their cell wall, which is still the best target for new antibiotics.

10 Feb 2015

CWRU researcher receives $3.9 million grant for HIV research

A researcher at Case Western Reserve University School of Medicine has been awarded $3.9 million to determine if the combination of the human immunodeficiency virus (HIV) and drug abuse is a double kick in the gut, leading to organ damage throughout the body.

10 Feb 2015

Duke University researchers devise new method to activate genes with light

Duke University researchers have devised a method to activate genes in any specific location or pattern in a lab dish with the flip of a light switch by crossing a bacterium's viral defense system with a flower's response to sunlight.

9 Feb 2015

Risks and benefits of fecal microbiota transplant

A woman successfully treated for a recurrent Clostridium difficile infection with stool from an overweight donor rapidly gained weight herself afterwards, becoming obese, according to a case report published in the new journal Open Forum Infectious Diseases.

9 Feb 2015

Research finding could help predict the next outbreak of plague

Biologists at the University of Oslo, Norway, are now making a giant effort to identify the relationship between climate change, rat infestations, and the many major plague epidemics throughout history. The knowledge may be used to predict the next plague outbreak.

9 Feb 2015

Investigators develop microbiome map of New York City subway system

The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs -- and even DNA fragments associated with anthrax and Bubonic plague -- according to a citywide microbiome map published today by Weill Cornell Medical College investigators.

9 Feb 2015

Bacteria News and Research

Elusys presents positive results of obiltoxaximab for treating inhalational anthrax, post-exposure prophylaxis

Biotech experts to establish ethical guidelines in cellular biotechnology at BEINGS 2015

RAB3GAP complex plays important role in autophagy

Oral pathogen protects different tumor cells from being killed by immune cells

Diabetes medication can help white blood cells fight bacterial infections

Health Canada: Parents advised not to feed honey to infants less than one year old

Standard cleaning procedures in retail delis may not eradicate Listeria pathogen, study shows

OSU researchers discover impact of antibiotics on microorganisms that live in animal's gut

Single genomic change can make beneficial bacteria into pathogenic bacteria

Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

University of Tokyo researchers reveal how TLR9 binds to pathogen DNA

IU researchers awarded NIH grant to develop new weapon to fight against antibiotic-resistant bacteria

CWRU researcher receives $3.9 million grant for HIV research

Duke University researchers devise new method to activate genes with light

Risks and benefits of fecal microbiota transplant

Research finding could help predict the next outbreak of plague

Investigators develop microbiome map of New York City subway system

Overview of chlamydia trachomatis infections

Study: Lyme disease costs the U.S. health care system up to $1.3 billion a year

Study: 45% of RTI patients inappropriately prescribed antibiotics in outpatient settings

Microbiology eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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