Bacteriophage News and Research

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Bacteriophages are small, virus-like organisms that infect bacteria. They are comprised of a protein capsule around an RNA or DNA genome.

Viruses exploit ability to sense the environment to maximize their infective yield

New UMBC-led research in Frontiers in Microbiology suggests that viruses are using information from their environment to "decide" when to sit tight inside their hosts and when to multiply and burst out, killing the host cell. The work has implications for antiviral drug development.

23 Sep 2022

Researchers find evidence of negative repercussions of immune history in SARS-CoV-2 infection

Researchers found proof of negative repercussions of immune history in SARS-CoV-2 infection.

30 Aug 2022

What is the efficacy of Grignard Pure™ against surrogate of SARS-CoV-2?

Researchers characterized the efficacy of Grignard Pure™ (GP) in inactivating MS2 bacteriophage, a non-enveloped viral microbe that has been used widely as a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) surrogate.

25 Aug 2022

Rice University researchers model a key mechanism by which DNA replicates

Knowing the structure of a complex biological system isn't nearly enough to understand how it works. It helps to know how the system moves.

10 Aug 2022

The impact of respiratory droplet volume and their evaporation kinetics on environmental stability of respiratory viruses

Researchers measured the impact of initial respiratory droplet volume and relative humidity on the environmental stability of respiratory viruses, including influenza A and SARS-CoV-2.

2 Aug 2022

Phage therapeutics can be used to fight multidrug-resistant pathogens

Scientists with the Texas A&M College of Agriculture and Life Sciences were among those providing the biochemical tools needed to help save a man's life through a unique emergency intervention in 2016.

27 Jul 2022

Using CRISPR to Lift the Lid on Probiotics

In this interview, we speak to Echo Pan, a Ph.D. student from North Carolina State University about her latest research that used CRISPR to uncover more on probiotics.

26 Jul 2022

A VSV-based COVID vaccine effective against SARS-CoV-2 variants

A new study discusses the development of recombinant vesicular stomatitis virus COVID-19 vaccines.

25 Jul 2022

Filter using whey protein nanofibrils and iron oxyhydroxides nanoparticles catches viruses, including SARS-CoV-2

A recent Swiss study posted to the bioRxiv* preprint server demonstrated that aerosol filters centered on granular protein nanofibrils and iron (Fe) oxyhydroxides nanoparticles could trap virus-containing aerosols.

4 Jul 2022

How do viruses evolve to infect new hosts?

Researchers discuss how protein thermostability prevents the misfolding of viral proteins from being heated.

7 Jun 2022

New funding boost to combat antibiotic resistance

Antibiotics have saved countless lives since they were introduced in the 1940s, curing infections and making procedures like chemotherapy and surgeries safer. But their effectiveness is waning.

19 May 2022

Researchers use bacteriophages to treat antibiotic-resistant mycobacterial lung infection

For the first time, researchers have successfully used bacteriophages – viruses that kill bacteria – to treat an antibiotic-resistant mycobacterial lung infection, clearing the way for a young National Jewish Health patient with cystic fibrosis to receive a life-saving lung transplant.

13 May 2022

The promise of RNA medicine is targeted and personalized

The development of messenger RNA (mRNA) vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has only increased the impetus in this field.

11 May 2022

Bacteria-mediated oral delivery of viral replicon-based mRNA vaccines

Scientists have discussed the possibilities of developing oral replicon-based mRNA vaccines against SARS-CoV-2.

4 May 2022

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

Researchers developed a mucosal vaccine for COVID-19 based on bacteriophage.

3 May 2022

Study shows circular RNA vaccine provides robust protection against SARS-CoV-2 in mice and rhesus macaques

Researchers investigated the effectiveness of a circRNA vaccine against SARS-CoV-2 and its Delta and Omicron variants, which elicited significant antibody and T-cell responses in mice and rhesus macaques.

6 Apr 2022

Current and future perspectives of mRNA technology

New research reports on the current and future perspectives on messenger ribonucleic acid technology, the platform on which the first successful COVID-19 vaccine was based.

8 Mar 2022

Photoinactivating effect of visible light on viruses

The current literature study focused on visible light inactivation investigations of viruses.

23 Feb 2022

New insights could help long-term care facilities enhance infection prevention and control measures

Findings from a study published today in the American Journal of Infection Control provide new insights that could help long-term care facilities assess the cleanliness of high-touch surfaces, and thereby enhance infection prevention and control measures designed to prevent serious diarrheal diseases and deaths among their residents.

17 Feb 2022

New passive air sampler clip can help assess personal exposure to SARS-CoV-2

Masks, social distancing, proper hygiene and ventilation can help reduce the transmission of COVID-19 in public places, but even with these measures, scientists have detected airborne SARS-CoV-2 in indoor settings.

11 Jan 2022