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Viewpoints: Conservative legal path on health law; Romney's plans for Medicare and vets; States moving on reform

A federal appeals court in the District of Columbia endorsed the constitutionality of health care reform this week in an opinion as notable for its authorship as for its legal reasoning. The majority opinion in the 2-to-1 decision was written by Judge Laurence Silberman, a stalwart of conservative jurisprudence whose views are said to be enormously influential in conservative legal circles.

14 Nov 2011

Cancer cells maintain rapid proliferation due to PK-M2 enzyme

Cancer cells maintain their life-style of extremely rapid growth and proliferation thanks to an enzyme called PK-M2 (pyruvate kinase M2) that alters the cells' ability to metabolize glucose - a phenomenon known as the Warburg effect.

3 Nov 2011

Nurse scientist recognized as AACN's 2012 Distinguished Research Lecturer

The American Association of Critical-Care Nurses (AACN) recently selected Martha A.Q. Curley, RN, PhD, FAAN, as its 2012 Distinguished Research Lecturer.

2 Nov 2011

Hippocampus supports both recollection and familiarity memories

Human memory has historically defied precise scientific description, its biological functions broadly but imperfectly defined in psychological terms. In a pair of papers published in the November 2 issue of The Journal of Neuroscience, researchers at the University of California, San Diego report a new methodology that more deeply parses how and where certain types of memories are processed in the brain, and challenges earlier assumptions about the role of the hippocampus.

2 Nov 2011

First report on how patterns of 5-hmC's distribution change in mouse brain during development

In 2009, the DNA alphabet expanded. Scientists discovered that an extra letter or "sixth nucleotide" was surprisingly abundant in DNA from stem cells and brain cells.

31 Oct 2011

Cigna third quarter adjusted income from operations increases to $325 million

Cigna Corporation today reported third quarter 2011 results that included strong revenue and earnings from each of our ongoing businesses, reflecting continued effective execution of the fundamentals supporting our long-term growth strategy.

29 Oct 2011

Whole genome sequencing study to determine causes of idiopathic human diseases

Scripps Health announced today it has launched an innovative clinical research study that is using whole genome sequencing to help determine the causes of idiopathic human diseases -- those serious, rare and perplexing health conditions that defy a diagnosis or are unresponsive to standard treatments.

18 Oct 2011

House approves bill to block abortion coverage

The measure, which among other things would ban women from using the health law's tax subsidies to purchase health insurance that includes abortion coverage, is unlikely to be considered in the Democratic-led Senate and has recieved a veto threat from President Barack Obama.

15 Oct 2011

First Edition: October 14, 2011

In today's headlines, more status report on the super committee's deficit-reduction deliberations.

14 Oct 2011

Incoming dean of Weill Cornell receives 2011 ICS Honorary Lifetime Membership

Dr. Laurie Glimcher, the incoming dean of Weill Cornell Medical College, has received the 2011 International Cytokine Society (ICS) Honorary Lifetime Membership, the Society's highest honor, for her pivotal contributions to cytokine research, particularly as it relates to immune response.

12 Oct 2011

Neuroscience 2011 conference to held in Washington

New research findings about the brain, nervous system, and related disorders will be presented at Neuroscience 2011 in Washington, Nov. 12-16. Among the many findings are how the brain adapts during development, learning, and decision-making; how genes and the environment work in tandem to influence behavior and disease; and how novel science is changing the understanding of pain, mental illness, and aging.

12 Oct 2011

Journal of Alzheimer's Disease supplement explores neuroimaging

Alzheimer's disease (AD) is a common problem that is becoming progressively burdensome throughout the world. A new supplement to the Journal of Alzheimer's Disease, Imaging the Alzheimer Brain, clearly shows that multiple imaging systems are now available to help understand, diagnose, and treat the disease.

12 Oct 2011

AzTE, Roche sign license agreement to develop revolutionary DNA sequencing system

Roche and Arizona Technology Enterprises (AzTE) announced today an agreement to license several technologies developed by Dr. Stuart Lindsay at the Biodesign Institute- at Arizona State University and Dr. Colin Nuckolls of the Columbia University Nanoscience Center for the development of a revolutionary DNA sequencing system.

12 Oct 2011

Roche NimbleGen launches pre-capture multiplex target enrichment protocol

With the decreasing cost and increasing throughput of sequencing, researchers require a high-performance, cost-effective sample preparation pipeline for targeted sequencing. To enable researchers to more readily match targeted sequencing sample preparation throughput to the ever increasing throughput of next-generation sequencing, Roche NimbleGen announces the imminent launch of a pre-capture multiplex target enrichment protocol.

11 Oct 2011

Two ACS members, editor of JACS to receive nation's highest honors in science and innovation

Peter J. Stang, Ph.D., editor of the Journal of the American Chemical Society (JACS), and American Chemical Society members Jacqueline K. Barton, Ph.D. and Rakesh Agrawal, Ph.D., are among 12 eminent researchers and inventors named by President Obama to receive the nation's highest honors in science and innovation.

30 Sep 2011

Radical change needed to deliver affordable cancer care in developed countries

Cancer is one of the leading causes of death and morbidity worldwide, and its economic burden grows year by year. In 2008, the worldwide cost of cancer due to premature death and disability, excluding direct medical costs, was estimated to be US$895 billion.

26 Sep 2011

Viewpoints: Ron Paul, USA Today on individual mandate; NYT's Greenhouse on court challenges to health law

Massachusetts leads the nation in health insurance coverage of its citizens, and Texas is dead last. You'd think that former Massachusetts governor Mitt Romney would be bragging about his role in making his state No. 1, and that Texas Gov. Rick Perry would be embarrassed by how poorly his state is doing. But that's not how the script is playing out … That's odd, though, because the mandate was born as a conservative response to President Clinton's much maligned health reform proposal.

23 Sep 2011

Scientists discover crucial connection in skin formation

Skin is the body's armor, protecting us from disease agents, injury, excessive water loss, and cold and heat. Yet mutations in a single gene, the gene for the protein p63, cause numerous diseases and malformations of the uppermost layer of skin - the epidermis - and other tissues. In the epidermis, these range from skin cancers to dysplasias that cause cracking, bleeding, infection, and discoloration.

21 Sep 2011

A code beyond DNA: Modified tRNA bases are characteristic of species

Our genetic code consists of four “letters” in the form of the nucleobases in our DNA and RNA. Three letters together form a “word” that are translated into an amino acid by tRNA and combined into proteins. Special markings subdivide the gene into active and inactive regions. A third possible level of information has so far received less attention: the chemical modification of tRNA nucleobases. In the journal Angewandte Chemie Thomas Carell and a team at the University of Munich have now demonstrated that tRNA modification profiles can be used for the characterization of species and the differentiation of pathogenic and nonpathogenic bacterial strains.

20 Sep 2011

Paper criticizes biomedical ontologies based purely on philosophical ideas

Professors and researchers from the Universidad Politécnica de Madrid's Facultad de Informática, Víctor Maojo, José Crespo, Miguel García Remesal, David Pérez del Rey and Diana de la Iglesia, and from Rutgers University, Casimir Kulikowski, have published an article in the Methods of Information in Medicine journal. This paper criticizes biomedical ontologies based purely on philosophical ideas and states a host of potential scientific constraints.

8 Sep 2011