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Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

While it's long been understood that predicting outcomes in patients with cancer requires considering many factors, such as patient history, genes and disease pathology, clinicians struggle with integrating this information to make decisions about patient care.

8 Aug 2022

New Oxford study examines the effectiveness of pharmacological treatments for insomnia

Two drugs, eszopiclone and lemborexant - both not currently licenced for the treatment of insomnia in the UK - were shown to perform better than others, both in the acute and long-term treatment of insomnia in adults, according to a new Oxford study exploring the pharmacological management of insomnia.

19 Jul 2022

GenomeBits representation of SARS-CoV-2 Delta and Omicron genome sequences

In a new study, researchers uncovered distinct genomic features of SARS-CoV-2 Delta and Omicron variants.

13 Jul 2022

Researchers report a non-canonical RNA secondary structure present in monkeypox virus variants

Researchers described the evolutionary profile of the monkeypox virus.

12 Jul 2022

Scientists examine the maturation of brain regions in preschoolers

As their brain regions linked to self-control mature, preschoolers improve in their ability to stop themselves from doing something, according to new research published in JNeurosci.

11 Jul 2022

Beyond COVID-19: the potential future applications of mRNA vaccines

Researchers described the production, mechanisms, and potential applications of mRNA vaccines.

6 Jul 2022

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

In a recent study published in the bioRxiv* preprint server, researchers at the Medical University of Innsbruck assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro mutations responsible for Paxlovid resistance. The 3-chymotrypsin-like protease (3CLPro), or main protease (Mpro), is the main protease found in coronaviruses.

6 Jul 2022

Two-step synthesis procedure produces amino acid Schiff base Cu (II) complexes within 10 minutes

Ever since their development in the late 19th century, Schiff bases have been a popular group of organic compounds, owing to their wide variety of desirable properties.

4 Jul 2022

Investigating the prerequisites for developing RNA-based antibiotics

In the fight against the Covid-19 pandemic, mRNA-based vaccines have impressively demonstrated their potential. Using this technology, scientists were able to rapidly develop and bring to market vaccines against SARS-CoV-2 that have been extremely effective at protecting millions of people against severe disease progression of COVID-19 or even death.

29 Jun 2022

Researchers identify an epigenetic signature associated to the development of MIS-C after COVID-19

Researchers from the Cancer Epigenetics group led by Dr. Manel Esteller at the Josep Carreras Leukaemia Research Institute and Dr. Aurora Pujol, from the Bellvitge Biomedical Research Institute, have identified an epigenetic signature associated to the development of the Multisystem Inflammatory Syndrome in Children (MIS-C) after a SARS-CoV-2 virus infection.

27 Jun 2022

Techniques used in weather forecasting can be repurposed to assess risk of COVID-19 exposure

Techniques used in weather forecasting can be repurposed to provide individuals with a personalized assessment of their risk of exposure to COVID-19 or other viruses, according to new research published by Caltech scientists.

23 Jun 2022

An integrated molecular diagnostic approach for detecting SARS-CoV-2 variants

Researchers developed an integrated approach combining NGS, molecular barcoding, machine learning, and bioinformatics to enable high-throughput detection of SARS-CoV-2 variants.

23 Jun 2022

Researchers identify biomarkers that could be targets for novel drugs to treat glioblastoma

Biomarkers that could be targets for novel drugs to treat glioblastoma brain tumors have been identified by investigators at Georgetown Lombardi Comprehensive Cancer Center, providing hope for a cancer that is highly lethal.

22 Jun 2022

SARS-CoV-2 variant-specific polymerase chain reaction assay for SARS-CoV-2 genomic surveillance

Researchers reported on the misclassification of the SARS-CoV-2 Omicron BA.1 subvariant as Omicron BA.2 subvariant in an automated variant-specific polymerase chain reaction analysis.

17 Jun 2022

The potential mechanisms of SARS-CoV-2 to induce DNA damage

Researchers described potential mechanisms of coronaviruses that could lead to DNA damage and the potential link between SARS-CoV-2 activity and such mechanisms.

14 Jun 2022

Deciphering the structure of nuclear pore complex piece by piece

Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work.

10 Jun 2022

Curia and Replicate Bioscience Enter Strategic Collaboration to Create Groundbreaking Development Platform for Self-Replicating RNA (srRNA)

From Curia 9 Jun 2022