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Breakthrough research opens door to potential new therapies for inflammatory diseases

Breakthrough research opens door to potential new therapies for inflammatory diseases

Scientists have made a major breakthrough in understanding the workings of the cellular machinery involved in a host of inflammatory diseases. [More]
Virginia Tech researchers identify novel compound that blocks growth of deadly fungus

Virginia Tech researchers identify novel compound that blocks growth of deadly fungus

Researchers with the Virginia Tech Center for Drug Discovery have identified a compound that blocks the growth of a fungus that causes deadly lung infections and allergic reactions in people with compromised immune systems. [More]
Scientists find way to reverse malfunctioning protein clumps involved in ALS

Scientists find way to reverse malfunctioning protein clumps involved in ALS

In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and spinal cord by jamming their cellular machinery. [More]
CUMC researchers uncover new details of intracellular channel that controls skeletal muscle

CUMC researchers uncover new details of intracellular channel that controls skeletal muscle

Using high-resolution electron microscopy, Columbia University Medical Center researchers have uncovered new details of the structure and function of an intracellular channel that controls the contraction of skeletal muscle. [More]
MSU experts pioneer pathways to new treatment options for pneumonia

MSU experts pioneer pathways to new treatment options for pneumonia

Streptococcus pneumoniae likely is not a term immediately recognizable by most individuals, even if they have had unpleasant run-ins with the common bacterium. However, experts at Mississippi State University are pioneering pathways to new treatment options. [More]
Experts receive $5.2 million NIH grant to develop affordable test for diagnosing Chagas disease

Experts receive $5.2 million NIH grant to develop affordable test for diagnosing Chagas disease

An international team of researchers led by infectious disease experts at the University of Georgia has received $5.2 million from the National Institutes of Health to develop a more accurate, affordable diagnostic test for Chagas disease, a parasitic infection that kills more than 50,000 people each year in Central and South America. [More]
Solid-state NMR in structural biology: an interview with Professor Tatyana Polenova

Solid-state NMR in structural biology: an interview with Professor Tatyana Polenova

My research lab studies several classes of systems. We are mostly interested in looking at large protein assemblies to understand their structure, dynamics and how their properties relate to their malfunction in disease. [More]
De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells

De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells

In reading, a bookmark tells where you stopped. Cells use bookmarks too, specific proteins that help the cell remember what collection of genes needs to be turned on again after the brief halt of gene expression during cell division. [More]
Researchers discover gene variants linked to thoracic aortic dissections

Researchers discover gene variants linked to thoracic aortic dissections

On Super Bowl Sunday, Tina Wilkins was relaxing in her recliner while she chatted on the phone with her mother and waited for the game to begin. She had recently lost 63 pounds and was in better shape than she had been in years. [More]
Desalination can increase prevalence of inadequate iodine intake

Desalination can increase prevalence of inadequate iodine intake

Hebrew University study suggests that desalination can dramatically increase the prevalence of inadequate iodine intake. [More]
Food intolerance testing: an interview with Dr Gill Hart

Food intolerance testing: an interview with Dr Gill Hart

Food intolerances are caused by adverse reactions to food or drink ingredients in your body. These are very different to food allergies. It is estimated that up to forty-five percent of the population suffers from food intolerances. [More]
Chemists develop one-step solution to make precursors for synthesis of drugs

Chemists develop one-step solution to make precursors for synthesis of drugs

A one-step solution to make nitrogen-laden molecular precursors for the preparation of drugs and other bioactive molecules has been discovered by researchers at Rice University, the University of Texas Southwestern Medical Center and Brigham Young University. [More]
Genome-wide studies reveal evolutionary conserved enzyme facilitates DNA replication

Genome-wide studies reveal evolutionary conserved enzyme facilitates DNA replication

Genome-wide studies of fission yeast (Schizosaccharomyces pombe) suggest that the evolutionary conserved enzyme Pfh1 helicase facilitates DNA synthesis by tracking along with the replication apparatus, promoting intact DNA synthesis at hard-to-replicate sites and consequently suppressing DNA damage. The findings are published in PLOS Genetics. [More]
Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

As health departments around the U.S. boost efforts to combat Zika, scientists are working on new ways to kill the mosquitoes that carry the virus. One approach involves understanding the molecular mechanisms that keep the bugs alive so we can then undermine them. [More]
Scientists discover potential new genetic causes for intellectual disability

Scientists discover potential new genetic causes for intellectual disability

An international group of researchers has for the first time identified a set of 30 inherited recessive genes that play a role in intellectual disability (ID), a neurodevelopmental disorder that, according to the Centers for Disease Control, affects as many as 213 million people around the world. [More]
Mathematical model explains molecular events linked to learning and memory formation

Mathematical model explains molecular events linked to learning and memory formation

A team of researchers has built a mathematical model that describes the molecular events associated with the beginning stage of learning and memory formation in the human brain. [More]
International conference on longevity to be held in Brussels for 3 days

International conference on longevity to be held in Brussels for 3 days

The Eurosymposium on Healthy Ageing is an international event that provides a unique opportunity for researchers, government officials, biotech executives, entrepreneurs, and non-governmental institutions from around the world to meet, network, and forge new scientific collaborations. [More]
Groundbreaking research unravels structure of infectious prions that cause mad cow disease

Groundbreaking research unravels structure of infectious prions that cause mad cow disease

Groundbreaking research from the University of Alberta has identified the structure of the infectious prion protein, the cause of "mad cow disease" or BSE, chronic wasting disease in deer and elk and Creutzfeldt-Jakob disease in humans, which has long remained a mystery. [More]
Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

In research published online today in Science, a team of scientists describe a new therapeutic strategy to target a hidden Achilles' heel shared by all known types of Ebola virus. [More]
Research could pave way for more effective and safer anti-epilepsy drugs

Research could pave way for more effective and safer anti-epilepsy drugs

Columbia University Medical Center researchers have discovered how a new epilepsy drug works, which may lead the way to even more effective and safer medications. [More]
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