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Mitosis study identifies new potential target for cancer therapy

Mitosis study identifies new potential target for cancer therapy

Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to cancer. Their hope now is that the detailed new characterization of the interaction will make it a target for exploring a new cancer therapy. [More]
Study shows how caffeine counteracts age-related cognitive deficits in animals

Study shows how caffeine counteracts age-related cognitive deficits in animals

A study published in the journal Scientific Reports from Nature publishing group, describes the mechanism by which caffeine counteracts age-related cognitive deficits in animals. [More]
New discovery could lead to effective treatment methods for cystitis

New discovery could lead to effective treatment methods for cystitis

Every year, millions of people are treated for cystitis, but despite its prevalence, the disease is still a scientific mystery. [More]
Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

A study in The Journal of Cell Biology by scientists at the University of Massachusetts Medical School reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool. [More]
New study finds contamination events near fracking gas drilling sites result of operational inefficiencies

New study finds contamination events near fracking gas drilling sites result of operational inefficiencies

Chemists at the University of Texas at Arlington have published a new study that indicates that highly variable contamination events registered in and around unconventional oil and gas developments are the result of operational inefficiencies and not inherent to the extraction process itself. [More]
Researchers find new way for early prediction of leukemic relapse

Researchers find new way for early prediction of leukemic relapse

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer. [More]
Curbing immune system infighting could make treatment more effective for pancreatic cancer

Curbing immune system infighting could make treatment more effective for pancreatic cancer

Internal conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer. [More]
Melatonin appears to suppress growth of breast cancer stem cells

Melatonin appears to suppress growth of breast cancer stem cells

Melatonin, a hormone produced in the human brain, appears to suppress the growth of breast cancer tumors. [More]
New MRI method detects low zinc levels to help identify healthy prostate tissue from cancer

New MRI method detects low zinc levels to help identify healthy prostate tissue from cancer

A novel MRI method that detects low levels of zinc ion can help distinguish healthy prostate tissue from cancer, UT Southwestern Medical Center radiologists have determined. [More]
Tel Aviv University researchers unravel how melanoma spreads to distant organs

Tel Aviv University researchers unravel how melanoma spreads to distant organs

In a landmark discovery, researchers at Tel Aviv University have unraveled the metastatic mechanism of melanoma, the most aggressive of all skin cancers. [More]
Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes

Food provides us with a variety of substances we need to maintain life. These substances are essential nutrients and are classified as macronutrients (water, protein, fats, and carbohydrates) and micronutrients (vitamins and minerals). [More]
Research shines more light on role of proteins in maintaining synaptic transmission

Research shines more light on role of proteins in maintaining synaptic transmission

Synapses are the power junctions that allow living creatures to function. Popularly associated with learning and memory, they play a more fundamental role in our existence by regulating everything from breathing, sleeping and waking and other bodily functions. [More]
BUSM researchers reveal why obese people develop insulin resistance and type 2 diabetes

BUSM researchers reveal why obese people develop insulin resistance and type 2 diabetes

Findings from Boston University School of Medicine, which appear in eLife, provide a possible explanation as to why most people who are obese develop insulin resistance and type 2 diabetes. [More]
Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Using technology they developed, UT Southwestern Medical Center researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing. [More]
Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

Scientists find new functions of ANG protein that plays key role in regulation of blood cell formation

Tufts Medical Center and Tufts University scientists have found exciting, new functions of the protein angiogenin that play a significant role in the regulation of blood cell formation, important in bone marrow transplantation and recovery from radiation-induced bone marrow failure. [More]
Scientists provide new insights into workings of cancer-linked potassium channel

Scientists provide new insights into workings of cancer-linked potassium channel

Most cells in the body carry on their surface tiny pores through which potassium ions travel. In controlling the flow of these positively charged ions, the channel helps the cell maintain its electrical balance. [More]
Cutting off fuel to cancer cells may be potential therapeutic strategy for Kras-driven lung cancers

Cutting off fuel to cancer cells may be potential therapeutic strategy for Kras-driven lung cancers

Research from investigators at Rutgers Cancer Institute of New Jersey and Princeton University has identified a new approach to cancer therapy in cutting off a cancer cell's 'fuel supply' by targeting a cellular survival mechanism known as autophagy. [More]
UH biologists developing strategies to help regenerate heart muscle cell formation

UH biologists developing strategies to help regenerate heart muscle cell formation

Cardiovascular diseases are the leading cause of death in the U.S. With one in every four deaths occurring each year, the five-year survival rate after a heart attack is worse than most cancers. [More]
Scientist receives $1.7 million grant to study how early life toxic exposures predispose to diabetes

Scientist receives $1.7 million grant to study how early life toxic exposures predispose to diabetes

Some studies indicate that early life exposure to pollutants such as PCBs and phthalates can predispose people to disease. Now environmental scientist Alicia Timme-Laragy at the University of Massachusetts Amherst has received a five-year, $1.7 million grant from the National Institute of Environmental Health Sciences for a multi-level study of early life exposure to environmental contaminants and aberrant pancreas development, which may predispose one to diabetes. [More]
New research examines biomechanics of galectin-3

New research examines biomechanics of galectin-3

A new study, published in Biochemistry this week, examines the biomechanics of sugar-seeking proteins. Specifically, it delves into galectin-3's interaction with glycosaminoglycans (GAG) and proteoglycans. [More]
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