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Researchers uncover structure of cancer cell receptor protein that paves way for drug development

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression. [More]
Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

Enzyme identified in baker's yeast can efficiently annihilate leukemia cells

An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells. [More]
Chemotherapy-induced senescent cells promote side effects and cancer relapse

Chemotherapy-induced senescent cells promote side effects and cancer relapse

Standard chemotherapy is a blunt force instrument against cancer - and it's a rare cancer patient who escapes debilitating side effects from systemic treatments that mostly affect dividing cells, both malignant and healthy, throughout the body. [More]
Metabolomics and NMR

Metabolomics and NMR

Bruker has been involved in the Phenome Center network since its beginning. Several years ago, the whole visionary concept of a global phenome network was actually born with Professor Jeremy Nicholson and Bruker BioSpin has been part of it since the early stages. [More]
Knowledge bank approach could help find best treatment option for AML patients

Knowledge bank approach could help find best treatment option for AML patients

An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalised therapy will be possible in the future for people with cancer. [More]
DNAstack receives NRC-IRAP funding to build cloud-based genomics software platform

DNAstack receives NRC-IRAP funding to build cloud-based genomics software platform

DNAstack, a Toronto based company, today is announcing the investment into its cloud-based genomics software platform from the National Research Council of Canada Industrial Research Assistance Program. [More]
Powerful version of anti-inflammatory molecule may help protect vision in diabetic retinopathy

Powerful version of anti-inflammatory molecule may help protect vision in diabetic retinopathy

A more powerful version of an anti-inflammatory molecule already circulating in our blood may help protect our vision in the face of diabetes. [More]
Two research studies on new molecules could potentially treat Alzheimer's disease

Two research studies on new molecules could potentially treat Alzheimer's disease

This year, results have been published of two significant research studies about molecules that could potentially treat Alzheimer's disease. [More]
New computational tool can predict personal cancer driver genes to optimize treatment

New computational tool can predict personal cancer driver genes to optimize treatment

Columbia University Medical Center researchers have created a computational tool that can rapidly predict which genes are implicated in an individual's cancer and recommend treatments. [More]
Generative AAE can be radically new way to discover drugs on demand

Generative AAE can be radically new way to discover drugs on demand

Scientists at the Pharmaceutical Artificial Intelligence group of Insilico Medicine, Inc, today announced the publication of a seminal paper demonstrating the application of generative adversarial autoencoders (AAEs) to generating new molecular fingerprints on demand. [More]
Danish researchers uncover bacteria’s secret code language

Danish researchers uncover bacteria’s secret code language

Antibiotic resistance in pathogenic bacteria is a growing global challenge. Danish researchers have now discovered that bacteria use a code language to avoid being controlled. [More]
Wellcome Trust Sanger Institute establishes spin-out company, Microbiotica

Wellcome Trust Sanger Institute establishes spin-out company, Microbiotica

Cambridge Innovation Capital plc, a Cambridge-based investor in technology and healthcare companies, and IP Group plc, the developer of intellectual property-based businesses, announce the creation of Microbiotica Ltd, a newly formed spin-out company from the UK’s Wellcome Trust Sanger Institute based at the Wellcome Genome Campus in Hinxton, Cambridge. [More]
Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Based on the study of cell signalling networks, the cell signals that drugs alter when they reach their target molecule, an exhaustive in silico analysis of the pairing of 64 therapeutic agents used to treat breast cancer (half already in use and the other half in clinical testing phase) has allowed researchers at the Institute for Research in Biomedicine to identify 10 new and previously untested combinations that hold potential for the treatment of breast cancer. [More]
Researchers use DNA markers to differentiate harmless species from deadly bacteria

Researchers use DNA markers to differentiate harmless species from deadly bacteria

The virulent pathogen that causes the disease tularemia, or "rabbit fever," was weaponized during past world wars and is considered a potential bioweapon. [More]
Researchers receive NIH grant to map molecular changes linked to physical movement

Researchers receive NIH grant to map molecular changes linked to physical movement

A research team led by Robert Gerszten, MD, Chief of Cardiovascular Medicine at Beth Israel Deaconess Medical Center and a Senior Associate Member of the Broad Institute, has received an award of more than $11 million as part of the Molecular Transducers of Physical Activity in Humans consortium, a large-scale initiative of the National Institutes of Health to investigate and map the molecular changes that occur in our bodies during and after exercise. [More]
AMP publishes joint guidelines for interpretation, reporting of sequence variants in cancer

AMP publishes joint guidelines for interpretation, reporting of sequence variants in cancer

The Association for Molecular Pathology (AMP), the premier global, non-profit molecular diagnostics professional society, today published guideline recommendations for both clinical laboratory professionals and oncologists that assess the status of next-generation sequencing (NGS)-based cancer tests and establish standardized classification, annotation, interpretation, and reporting conventions for somatic sequence variants. [More]
Johns Hopkins scientists create bioinformatics tool to evaluate cancer driver gene prediction methods

Johns Hopkins scientists create bioinformatics tool to evaluate cancer driver gene prediction methods

In their search for new ways to treat cancer, many scientists are using a high-tech process called genome sequencing to hunt for genetic mutations that encourage tumor cells to thrive. [More]
U-M awarded NIH grant to investigate molecular changes that occur during and after physical activity

U-M awarded NIH grant to investigate molecular changes that occur during and after physical activity

The University of Michigan was recently awarded $8.2 million from the National Institutes of Health to investigate the molecular changes that occur during and after physical activity. [More]
Researchers develop new method to identify antigens for cancer treatment

Researchers develop new method to identify antigens for cancer treatment

New cancer therapies harness the immune system to fight tumors. One of the main principles behind these therapies is to find out precisely which molecules on cancer cells trigger an immune response. [More]
Scientists discover new biomarker to help determine aggressiveness of brain cancer

Scientists discover new biomarker to help determine aggressiveness of brain cancer

Researchers at UT Southwestern Medical Center have found a new biomarker for glioma, a common type of brain cancer, that can help doctors determine how aggressive a cancer is and that could eventually help determine the best course of treatment. [More]
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