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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.
Autism Speaks grants $1M to Children's Hospital Los Angeles to improve GI symptoms associated with ASD

Autism Speaks grants $1M to Children's Hospital Los Angeles to improve GI symptoms associated with ASD

Pat Levitt, PhD, Simms/Mann Chair in Developmental Neurogenetics at Children's Hospital Los Angeles, has received a grant of nearly $1 million from Autism Speaks, the world's leading autism science and advocacy organization. [More]
Novel 'designer' nanodevice could improve cancer diagnostics, treatment

Novel 'designer' nanodevice could improve cancer diagnostics, treatment

Cancer diagnostics and treatment options could be drastically improved with the creation of a 'designer' nanodevice being developed by researchers from the UK, Italy, the US and Argentina. [More]
Researchers define the process of Parkinson's disease using genetic mouse model

Researchers define the process of Parkinson's disease using genetic mouse model

Parkinson's Disease is the second most common neurodegenerative disorder. In Germany alone, almost half a million people are affected. The focus of the disease is the progressive degeneration of dopamine-producing nerve cells in a certain region of the midbrain, the substantia nigra. Misfolded proteins are the cause. Until recently, it was unclear why damage is confined to specific nerve cells. [More]
Intake of arsenic linked to cardiovascular disease, diabetes

Intake of arsenic linked to cardiovascular disease, diabetes

Associated with various types of cancer such as skin and liver, the intake of arsenic it is also linked to cardiovascular disease and diabetes. According to a long-term research conducted by experts from the Center for Research and Advanced Studies it was determined that this metalloid inhibits enzymes associated with antioxidant protection. [More]

UL research unlocks major scientific challenge that has potential for rapid diagnostics tools

Research from the University of Limerick has unlocked a major scientific challenge which has exciting potential for point of care medical tests. The research entitled ‘Nanoelectrical analysis of single molecules and atomic-scale materials at the solid/liquid interface’ is reported online in Nature Materials. [More]
Research findings point toward new therapeutic target for aggressive breast cancer

Research findings point toward new therapeutic target for aggressive breast cancer

One of the first-known oncogenes has a protein partner that helps breast cancer proliferate and when it's blocked, so is the cancer, scientists report. [More]
Obesity greatly accelerates aging of the liver

Obesity greatly accelerates aging of the liver

Using a recently developed biomarker of aging known as an epigenetic clock, UCLA researchers working closely with a German team of investigators have found for the first time that obesity greatly accelerates aging of the liver. This finding could explain the early onset of many age-related diseases, including liver cancer, in obese subjects [More]
Recent clinical study sheds light on potential approach to more personalized care for pancreatic cancer

Recent clinical study sheds light on potential approach to more personalized care for pancreatic cancer

Pancreatic cancer is one of the deadliest cancers. Even with aggressive treatment, the prognosis is poor, with various factors stacking the odds against successful treatment: early detection is uncommon, it tends to spread quickly and recurrence is likely. However, several newer approaches show promise in increasing the response rate to pancreatic cancer treatment. [More]
RNA molecules in tissue, urine samples can detect prostate cancer

RNA molecules in tissue, urine samples can detect prostate cancer

Researchers at Sanford-Burnham Medical Research Institute have identified a set of RNA molecules that are detectable in tissue samples and urine of prostate cancer patients but not in normal healthy individuals. [More]
Scientists use novel way to identify new gene linked to Alzheimer's

Scientists use novel way to identify new gene linked to Alzheimer's

Scientists at The University of Manchester have used a new way of working to identify a new gene linked to neurodegenerative diseases such as Alzheimer's. The discovery fills in another piece of the jigsaw when it comes to identifying people most at risk of developing the condition. [More]
Astute Medical to get $30 million from CRG to support commercialization of NephroCheck Test System

Astute Medical to get $30 million from CRG to support commercialization of NephroCheck Test System

Astute Medical, Inc. and CRG today announced that Astute recently achieved a milestone under the terms of its existing term loan agreement with CRG. Under the term loan agreement, CRG will provide up to $30 million to support the commercialization of the NephroCheck Test System. [More]
University of Luxembourg researchers identify potential new ways to test colorectal cancer

University of Luxembourg researchers identify potential new ways to test colorectal cancer

Researchers at the University of Luxembourg have identified potential new ways to test for the first signs of one of the most deadly types of cancer: colorectal cancer. They have found new "biomarkers": molecules whose increased presence or absence in tissue suggests the development of tumorous cells. These indicators could help detect colorectal cancer at an early stage, predict its severity or even offer new treatments. [More]
GeneSolve to license its health optimization system to highly qualified doctors

GeneSolve to license its health optimization system to highly qualified doctors

GeneSolve announced today that it will begin licensing its proprietary health optimization system to a network of highly qualified doctors nationwide. [More]

MyCartis announces launch of digital multiplex biomarker analysis platform

MyCartis today announced the launch of Evalution, a multiplex biomarker analysis platform for the life sciences research market. [More]
Scientists identify new biomarker for diagnosing cause of thyroid cancer

Scientists identify new biomarker for diagnosing cause of thyroid cancer

The expression of the protein CLIP2 provides information on whether a papillary thyroid carcinoma was induced by radiation or had a sporadic origin. With this discovery, scientists from the Helmholtz Zentrum München have identified a new biomarker for the diagnosis of the cancer cause. [More]
NanoString, BWH partner to translate genomic biomarker discoveries into clinical cancer diagnostics

NanoString, BWH partner to translate genomic biomarker discoveries into clinical cancer diagnostics

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced that it has signed a multi-year, multi-investigator research collaboration with Harvard-affiliated Brigham and Women's Hospital to accelerate the translation of genomic biomarker discoveries into clinical cancer diagnostics. [More]
Exclusive partnership brings together next-generation proteomics and next-generation sequencing

Exclusive partnership brings together next-generation proteomics and next-generation sequencing

AB SCIEX and Illumina (NASDAQ: ILMN) announced today the OneOmics™ project, an exclusive partnership to bring together SWATH™-based next-generation proteomics (NGP) and next-generation sequencing (NGS) tools in a cloud computing environment. [More]
Researchers identify biomarker that can predict GS7 prostate cancer patients

Researchers identify biomarker that can predict GS7 prostate cancer patients

Researchers at The University of Texas MD Anderson Cancer Center have identified a biomarker living next door to the KLK3 gene that can predict which GS7 prostate cancer patients will have a more aggressive form of cancer. [More]
Brain structure changes differ between schizophrenia symptoms

Brain structure changes differ between schizophrenia symptoms

The specific areas of the brain with reduced grey matter in patients with schizophrenia differ according to whether they have predominant positive, negative or disorganised symptoms, research suggests. [More]
Ardelyx announces positive Phase 2b results for tenapanor in IBS-C patients

Ardelyx announces positive Phase 2b results for tenapanor in IBS-C patients

Ardelyx, Inc., a clinical-stage biopharmaceutical company focused on cardio-renal, gastrointestinal and metabolic diseases, today announced positive results from its 371 patient Phase 2b clinical trial evaluating tenapanor in patients with constipation-predominant irritable bowel syndrome (IBS-C). [More]