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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.
Researchers show how microRNAs play key role in tumor progression and response to radiation

Researchers show how microRNAs play key role in tumor progression and response to radiation

OHSU researcher Sudarshan Anand, Ph.D., has a contemporary analogy to describe microRNA: "I sometimes compare MicroRNA to tweets -- they're short, transient and constantly changing." [More]
Applying quantitative microscopy to live cells

Applying quantitative microscopy to live cells

Microscopy's got a long history. It was developed about 350 years ago for scientists to visualize things they could discern, but not describe. The two pioneers of microscopy were Antoine van Leeuwenhoek, who developed the first microscope and soon after the renowned scientist, Robert Hooke. [More]
NSF awards grant to advance new diagnostic test for fatal gastrointestinal disease in pre-term infants

NSF awards grant to advance new diagnostic test for fatal gastrointestinal disease in pre-term infants

The National Science Foundation has chosen an LSU Health New Orleans team that developed a test for the early detection of a potentially life-threatening gastrointestinal disease affecting pre-term, low birthweight babies to receive expert guidance to move the technology forward. [More]
Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease (AD). [More]
Aerobic activity offers greater preservation of brain volume, improves cognitive performance

Aerobic activity offers greater preservation of brain volume, improves cognitive performance

Using a new MRI technique, researchers found that adults with mild cognitive impairment (MCI) who exercised four times a week over a six-month period experienced an increase in brain volume in specific, or local, areas of the brain, but adults who participated in aerobic exercise experienced greater gains than those who just stretched. [More]
Johns Hopkins researchers find evidence of brain injury in young NFL players

Johns Hopkins researchers find evidence of brain injury in young NFL players

In a small study of young or recently retired NFL players, researchers at Johns Hopkins report finding evidence of brain injury and repair that is visible on imaging from the players compared to a control group of men without a history of concussion. [More]
Inflammatory marker detected in blood tests can better predict risk of death, study suggests

Inflammatory marker detected in blood tests can better predict risk of death, study suggests

A new study looking at deaths from cancer, cardiovascular disease and all causes suggests that an inflammatory marker detected in blood tests in middle-aged adults can better predict the risk of death compared with another similar biomarker. [More]
Mayo Clinic researchers discover potential cause and new treatment for rare soft tissue cancer

Mayo Clinic researchers discover potential cause and new treatment for rare soft tissue cancer

Researchers at Mayo Clinic Center for Individualized Medicine have discovered a potential cause and a promising new treatment for inflammatory myofibroblastic tumors, a rare soft tissue cancer that does not respond to radiation or chemotherapy. [More]
Music lessons increase brain fiber connections in children

Music lessons increase brain fiber connections in children

Taking music lessons increases brain fiber connections in children and may be useful in treating autism and Attention Deficit Hyperactivity Disorder (ADHD), according to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA). [More]
Researchers focus on optimal use of immune agents in frontline setting for NSCLC treatment

Researchers focus on optimal use of immune agents in frontline setting for NSCLC treatment

Immunotherapy continues to revolutionize the field of non-small cell lung cancer (NSCLC), with researchers now focusing on the optimal use of immune agents in the frontline setting. [More]
BAG3 protein plays protective role by limiting reperfusion injury to the heart

BAG3 protein plays protective role by limiting reperfusion injury to the heart

The inability of cells to eliminate damaged proteins and organelles following the blockage of a coronary artery and its subsequent re-opening with angioplasty or medications - a sequence known as ischemia/reperfusion - often results in irreparable damage to the heart muscle. [More]
Purdue University biochemist develops novel method for identifying cancer biomarkers

Purdue University biochemist develops novel method for identifying cancer biomarkers

A Purdue University biochemist has developed a novel method for detecting certain types of proteins that serve as indicators for cancer and other diseases. [More]
How toxic is your stress?

How toxic is your stress?

The term “stress” originates not in our minds or bodies, but from physics. It is the internal forces generated in an object in response to an external load. In the 1950s, Hans Selye adopted the term to characterize how living organisms change... [More]
Researchers identify new biomarker in spinal fluid and blood serum of patients with neurological disorder

Researchers identify new biomarker in spinal fluid and blood serum of patients with neurological disorder

Research from Mayo Clinic included in the November issue of JAMA Neurology identifies a new biomarker for brain and spinal cord inflammation, allowing for faster diagnosis and treatment of patients. [More]
NSU researchers learn more about Gulf War illness to help veterans

NSU researchers learn more about Gulf War illness to help veterans

As the nation honors our veterans on November 11, we must pause to remember the long-lasting health effects soldiers experience not only from bullets or bombs, but from exposure to unexplained pesticides, radiation or other toxins during their time in the service. [More]
Neuroimaging markers may help predict psychotherapy response in patients with depression, anxiety

Neuroimaging markers may help predict psychotherapy response in patients with depression, anxiety

Brain imaging scans may one day provide useful information on the response to psychotherapy in patients with depression or anxiety, according to a review of current research in the November/December issue of the Harvard Review of Psychiatry, published by Wolters Kluwer. [More]
Researchers develop new blood test that can accurately diagnose concussions

Researchers develop new blood test that can accurately diagnose concussions

Scientists from Children's Health Research Institute, a program of Lawson Health Research Institute, and Western University have developed a new blood test that identifies with greater than 90 per cent certainty whether or not an adolescent athlete has suffered a concussion. [More]
Study explores biological marker to predict individual response to drug treatment for combat PTSD

Study explores biological marker to predict individual response to drug treatment for combat PTSD

Treatment with the drug prazosin effectively reduces symptoms of posttraumatic stress disorder (PTSD) for many people, but about one third of patients don't respond to the treatment at all. [More]
Brain inflammation may have direct involvement in development of chronic traumatic encephalopathy

Brain inflammation may have direct involvement in development of chronic traumatic encephalopathy

For the first time, researchers have shown that inflammation in the brain may have direct involvement in the development of chronic traumatic encephalopathy (CTE). In addition, they found that the number of years one plays contact sports may predict the occurrence of CTE and that this association is partly due to increased inflammation in the brain. [More]
New study to explore impact of vitamin K supplement on cardiovascular health of obese children

New study to explore impact of vitamin K supplement on cardiovascular health of obese children

Researchers want to know whether a vitamin K supplement is an effective, inexpensive way to help reduce the cardiovascular risk of obese children. [More]
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