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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.
Mucus dehydration may contribute to chronic bronchitis

Mucus dehydration may contribute to chronic bronchitis

Mucus dehydration may lead to reduced mucociliary clearance and symptoms of chronic bronchitis, research suggests. [More]
UF research opens door to better diagnosis and treatment of Parkinson's disease

UF research opens door to better diagnosis and treatment of Parkinson's disease

University of Florida researchers have identified a biomarker that shows the progression of Parkinson's disease in the brain, opening the door to better diagnosis and treatment of the degenerative disease. [More]
New testing method could help get faster results, reduce volume of urine needed for sample

New testing method could help get faster results, reduce volume of urine needed for sample

If you've been to the doctor, you probably know what to do when you're handed a plastic cup and shown to the bathroom. Most patients hand over the sample and give little thought to what happens when it's shipped to the lab for analysis. Ken Marcus and his students are the exceptions. They have developed a new testing method that they believe will reduce costs, get faster results and lower the volume of urine needed for a sample. [More]
Pitt scientists identify two new classes of RNAs closely associated with cancer biomarker

Pitt scientists identify two new classes of RNAs closely associated with cancer biomarker

Researchers at the University of Pittsburgh School of Medicine have identified two new classes of RNAs that are closely associated with a protein known to be a prognostic biomarker for breast cancer and could play a role in progression of prostate cancer. [More]
Celgene to use Cypher's Coral technology to find novel genomic biomarkers

Celgene to use Cypher's Coral technology to find novel genomic biomarkers

Cypher Genomics, Inc., a leading genome informatics company, today announced a collaboration with Celgene Corporation to apply Cypher's Coral technology to discover novel genomic biomarkers that associate with patient response to innovative medicines. [More]
Johns Hopkins researchers identify new therapy to treat lung cancer

Johns Hopkins researchers identify new therapy to treat lung cancer

A multidisciplinary team led by Johns Hopkins researcher Venu Raman, Ph.D., with notable contributions from Guus Bol, Farhad Vesuna and Phuoc Tran of Johns Hopkins, has identified a new therapy for lung cancer, the most common cancer worldwide. The therapy has been in development for six years and involves a first-in-class molecule designed by the team. [More]
Ardelyx reports positive results from tenapanor Phase 2b clinical trial in IBS-C patients

Ardelyx reports positive results from tenapanor Phase 2b clinical trial in IBS-C patients

Ardelyx, Inc., a clinical-stage biopharmaceutical company focused on cardio-renal, gastrointestinal, and metabolic diseases, today presented Phase 2b clinical trial results that demonstrated statistically significant and clinically meaningful improvement in IBS-C symptoms for tenapanor-treated patients compared to patients receiving placebo. [More]
Researchers reveal molecular steps that allow pancreatic cancer to spread to the liver

Researchers reveal molecular steps that allow pancreatic cancer to spread to the liver

An international team led by Weill Cornell Medical College investigators has illuminated the precise molecular steps that enable pancreatic cancer to spread to the liver -- the event that makes the most common form of the disease lethal. By understanding this process, investigators say their discovery can lead to targeted treatments that delay metastasis, and could offer clinicians a new biomarker to test for the earliest signs of pancreatic cancer. [More]
Simple blood test can predict evidence of TBI on radiographic imaging, injury severity

Simple blood test can predict evidence of TBI on radiographic imaging, injury severity

New study results show that a simple blood test to measure brain-specific proteins released after a person suffers a traumatic brain injury (TBI) can reliably predict both evidence of TBI on radiographic imaging and injury severity. [More]

Commonwealth announces availability of new ELISA-based blood test to quickly and reliably diagnose IBS

Commonwealth Laboratories, Inc. announced today the availability of IBSchek, a new blood test designed to help physicians quickly and reliably diagnose Irritable Bowel Syndrome (IBS). [More]
Simple blood tests diagnose irritable bowel syndrome quickly and accurately

Simple blood tests diagnose irritable bowel syndrome quickly and accurately

Millions of people afflicted by irritable bowel syndrome can now be diagnosed quickly and accurately with two simple blood tests developed by a Cedars-Sinai gastroenterologist. [More]
Denali launched to discover, develop effective medicines for neurodegenerative diseases

Denali launched to discover, develop effective medicines for neurodegenerative diseases

Denali Therapeutics Inc., a new biotechnology company focused on developing effective therapies for neurodegenerative diseases, announced today that it has launched with an initial investment commitment of $217 million. [More]
Workplace mindfulness-based intervention reduces stress levels of employees

Workplace mindfulness-based intervention reduces stress levels of employees

A study by researchers at The Ohio State University Wexner Medical Center found that a workplace mindfulness-based intervention reduced stress levels of employees exposed to a highly stressful occupational environment. [More]
New method may help determine potential indicator of stress, neurological disorders

New method may help determine potential indicator of stress, neurological disorders

A research collaboration between the universities of Oslo and Aarhus has resulted in the development of a new method with diagnostic potential. The new method that combines phase extraction with an enzymatic reaction may eventually be used for an improved and faster screening analysis of isatin as a potential indicator of stress and neurological disorders. [More]
Workplace mindfulness-based intervention reduces stress levels and risk of burnout

Workplace mindfulness-based intervention reduces stress levels and risk of burnout

A study by researchers at The Ohio State University Wexner Medical Center found that a workplace mindfulness-based intervention reduced stress levels of employees exposed to a highly stressful occupational environment. [More]
Removing bacterial biofilms could help prevent and treat colon cancers, study suggests

Removing bacterial biofilms could help prevent and treat colon cancers, study suggests

A team led by scientists at The Scripps Research Institute and Johns Hopkins University School of Medicine has uncovered a big clue to how bacteria may promote some colon cancers. [More]
Stanford University professor named recipient of 2015 ECOG-ACRIN Young Investigator Award

Stanford University professor named recipient of 2015 ECOG-ACRIN Young Investigator Award

Heather Wakelee, MD, is the recipient of the 2015 ECOG-ACRIN Young Investigator Award, the ECOG-ACRIN Cancer Research Group announced today. Dr. Wakelee is associate professor of medicine in the Division of Oncology at the Stanford University School of Medicine in Stanford, Calif. [More]
First patient receives new 'resistance-busting' experimental skin cancer drug

First patient receives new 'resistance-busting' experimental skin cancer drug

A patient has become the first to receive a new 'resistance-busting' experimental skin cancer drug with the launch of a phase I clinical trial. The patient has received a new panRAF inhibitor - a new type of drug under development to address the problem of drug resistance in advanced skin cancer and a number of other cancer types. [More]
Neurocrine reports net loss of $1.2 million for first quarter 2015

Neurocrine reports net loss of $1.2 million for first quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter ended March 31, 2015. For the first quarter of 2015, the Company reported a net loss of $1.2 million, or $0.01 loss per share, compared to a net loss of $11.8 million, or $0.17 loss per share, for the same period in 2014. [More]
CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Blood-based biomarkers such as circulating tumor cells (CTCs), circulating free DNA (cfDNA), circulating tumor DNA (ctDNA) and microRNAs (miRNAs) are potential indicators for the tumor burden of patients living with cancer. [More]
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