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Hydroxyurea therapy offers safe, effective disease management of SCA

Hydroxyurea therapy offers safe, effective disease management of SCA

Conclusive data show that hydroxyurea therapy offers safe and effective disease management of sickle cell anemia (SCA) and reduces the risk of stroke, prompting early termination by the National Heart Lung and Blood Institute of a key clinical trial studying the drug's efficacy. [More]
New drug shows promise against treatment-resistant non-small cell lung cancer

New drug shows promise against treatment-resistant non-small cell lung cancer

A new drug that targets not only common cancer-causing genetic mutations in patients with non-small cell lung cancer (NSCLC), but also a form of the mutation that causes resistance to treatment, has shown promising results in patients in a phase I/II clinical trial. [More]
Digoxin drug associated with higher risk of death, hospitalization among adults with atrial fibrillation

Digoxin drug associated with higher risk of death, hospitalization among adults with atrial fibrillation

Digoxin, a drug commonly used to treat heart conditions, was associated with a 71 percent higher risk of death and a 63 percent higher risk of hospitalization among adults with diagnosed atrial fibrillation and no evidence of heart failure, according to a Kaiser Permanente study that appears in the current online issue of Circulation: Arrhythmia and Electrophysiology. [More]
Investigational drug maintains normal potassium levels in patients with chronic kidney disease

Investigational drug maintains normal potassium levels in patients with chronic kidney disease

Research published today found that the investigational drug patiromer decreased high potassium levels and maintained normal potassium levels in patients with chronic kidney disease. The results of a multicenter trial appear in the New England Journal of Medicine. [More]
Abaxis completes acquisition of QCR & Trio Diagnostics

Abaxis completes acquisition of QCR & Trio Diagnostics

Abaxis, Inc., a medical products company manufacturing point-of-care instruments and consumables for the medical, research, and veterinary markets worldwide and providing reference lab services to the veterinary and research markets in the United States, announced today the completion of a stock purchase agreement to acquire 100% of QCR & Trio Diagnostics Limited, a United Kingdom based distribution organization. [More]
High-quality U.S. hospitals also provide low-cost care for children undergoing heart surgery

High-quality U.S. hospitals also provide low-cost care for children undergoing heart surgery

U.S. children's hospitals delivering the highest-quality care for children undergoing heart surgery, also appear to provide care most efficiently at a low cost, according to research led by the University of Michigan and presented Tuesday at the American Heart Association Scientific Sessions in Chicago. [More]
Surgical membrane delivers healing action of vitamin A

Surgical membrane delivers healing action of vitamin A

When blood vessels are damaged through surgery, it can trigger an endless cycle of scarring and repair. [More]
New treatment for Marfan syndrome works as well as beta blockers

New treatment for Marfan syndrome works as well as beta blockers

A new treatment for Marfan syndrome, a rare genetic disease that can lead to heart problems, works as well as the currently recommended medical therapy, beta blockers, according to an article in the New England Journal of Medicine. [More]
Obese people experience silent cardiac damage that fuels risk for heart failure

Obese people experience silent cardiac damage that fuels risk for heart failure

Using an ultrasensitive blood test to detect the presence of a protein that heralds heart muscle injury, researchers from Johns Hopkins and elsewhere have found that obese people without overt heart disease experience silent cardiac damage that fuels their risk for heart failure down the road. [More]
Snus consumption in Norway is highest among young people

Snus consumption in Norway is highest among young people

The increase in Scandinavian snus consumption in Norway is highest among young people, according to a new report from the Norwegian Institute of Public Health. [More]
Children of women who work full time get fewer hours of sleep, have higher BMIs

Children of women who work full time get fewer hours of sleep, have higher BMIs

The majority of preschoolers may not be getting the amount of sleep they need each night, placing them at higher risk of being overweight or obese within a year, according to a new study. [More]
Training medical students on handheld ultrasound device can enhance their physical diagnosis

Training medical students on handheld ultrasound device can enhance their physical diagnosis

A new study by researchers from Icahn School of Medicine at Mount Sinai found that training medical students to use a handheld ultrasound device can enhance the accuracy of their physical diagnosis. [More]
No added benefit proven for empagliflozin in type 2 diabetes

No added benefit proven for empagliflozin in type 2 diabetes

Empagliflozin (trade name Jardiance) has been approved since May 2014 for adults with type 2 diabetes mellitus in whom diet and exercise alone do not provide adequate glycaemic control. [More]
Infections due to Staphylococcus aureus bacterium aggravate neurodermatitis

Infections due to Staphylococcus aureus bacterium aggravate neurodermatitis

Because the skin and its function as a barrier are severely compromised in neurodermatitis patients, a large number of bacterial species are able to multiply - including the bacterium Staphylococcus aureus. [More]
Study shows blood pressure medication is not linked to breast cancer

Study shows blood pressure medication is not linked to breast cancer

Women who take a common type of medication to control their blood pressure are not at increased risk of developing breast cancer due to the drug, according to new study by researchers at the Intermountain Medical Center Heart Institute in Murray, Utah. [More]
New combination therapy improves survival in patients with advanced ovarian cancer

New combination therapy improves survival in patients with advanced ovarian cancer

Epithelial ovarian cancer is the most lethal cancer of the female reproductive organs, with more than 200,000 new cases and more than 125,000 deaths each year worldwide. [More]
Personalized dietary advice based on person's genetic makeup improves eating habits

Personalized dietary advice based on person's genetic makeup improves eating habits

Personalized dietary advice based on a person's genetic makeup improves eating habits compared to current "one-size-fits-all" dietary recommendations, says a University of Toronto researcher. [More]
Excess fat in lungs may cause pulmonary fibrosis

Excess fat in lungs may cause pulmonary fibrosis

Pulmonary fibrosis has no cure. It's caused by scarring that seems to feed on itself, with the tougher, less elastic tissue replacing the ever moving and stretching lung, making it increasingly difficult for patients to breathe. [More]
Auxilium Pharmaceuticals presents STENDRA clinical data for ED treatment at SMSNA Scientific Meeting

Auxilium Pharmaceuticals presents STENDRA clinical data for ED treatment at SMSNA Scientific Meeting

Auxilium Pharmaceuticals, Inc., a specialty biopharmaceutical company, today announced that data were presented regarding the use of STENDRA® (avanafil) tablets for the treatment of erectile dysfunction (ED) at the 20th Annual Fall Scientific Meeting of the Sexual Medicine Society of North America (SMSNA) held in Miami from November 20-23, 2014. [More]
Special receptor signalling mediates astrocytic hyperactivity in  Alzheimer's disease mouse model

Special receptor signalling mediates astrocytic hyperactivity in Alzheimer's disease mouse model

It has long been known that astrocytes change their shapes as a consequence of Alzheimer's. Cells located near the "plaques", as the protein deposits typical for this disease are called, grow in size and form additional extensions. [More]