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Knowledge bank approach could help find best treatment option for AML patients

Knowledge bank approach could help find best treatment option for AML patients

An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalised therapy will be possible in the future for people with cancer. [More]
Inhibition of EZH2 protein could be new strategy to treat multiple myeloma

Inhibition of EZH2 protein could be new strategy to treat multiple myeloma

In a study published in the scientific journal Oncotarget, researchers from Uppsala University show how the protein EZH2 affects the development of multiple myeloma, and that inhibition of EZH2 could be used as a new strategy to treat the disease. [More]
Scientists find new treatment option for rare autoimmune disease

Scientists find new treatment option for rare autoimmune disease

Anti-NMDA receptor encephalitis is an inflammatory disease that affects the central nervous system. [More]
Study shows promising results for treating lymphoma patients with immune cell therapy

Study shows promising results for treating lymphoma patients with immune cell therapy

Lymphoma is the most common blood cancer. The disease occurs when immune cells called lymphocytes multiply uncontrollably. Cancerous lymphocytes can travel throughout the body and form lymph node tumors. [More]
Researchers identify possible treatment targets for myelodysplasia syndromes

Researchers identify possible treatment targets for myelodysplasia syndromes

Cincinnati Children's researchers report in Nature Immunology a new mechanism that controls blood cell function and several possible molecular targets for treating myelodysplasia syndromes (MDS) - a group of pre-malignant disorders in which bone marrow does not produce enough healthy blood cells. [More]
Whitehead Institute researchers identify mechanism underlying cancer drug-resistance

Whitehead Institute researchers identify mechanism underlying cancer drug-resistance

The use of proteasome inhibitors to treat cancer has been greatly limited by the ability of cancer cells to develop resistance to these drugs. [More]
New technology that increases Natural Killer cells to stop cancers gets licensed

New technology that increases Natural Killer cells to stop cancers gets licensed

Our bodies contain Natural Killer (NK) cells - an army that stops cancers and viruses before they can make us sick. [More]
Defective ribosomes linked to aggressive form of multiple myeloma

Defective ribosomes linked to aggressive form of multiple myeloma

20 to 40 percent of the patients with multiple myeloma - a type of leukaemia - have a defect in the ribosome, the protein factory of the cell. [More]
Personalized cancer vaccine improves outcomes for patients with AML, clinical study shows

Personalized cancer vaccine improves outcomes for patients with AML, clinical study shows

A personalized cancer vaccine markedly improved outcomes for patients suffering from acute myeloid leukemia (AML), a potentially lethal blood cancer, in a clinical trial led by investigators at Beth Israel Deaconess Medical Center. [More]
Hallucinogenic drug offers relief for people with cancer-related anxiety or depression

Hallucinogenic drug offers relief for people with cancer-related anxiety or depression

In a small double-blind study, Johns Hopkins researchers report that a substantial majority of people suffering cancer-related anxiety or depression found considerable relief for up to six months from a single large dose of psilocybin -- the active compound in hallucinogenic "magic mushrooms." [More]
Sheffield haematologist wins prestigious Anthony Nolan Supporter Award

Sheffield haematologist wins prestigious Anthony Nolan Supporter Award

Professor John Snowden, Consultant Haematologist at Sheffield Teaching Hospitals NHS Foundation Trust, was presented with a national award by the blood cancer charity Anthony Nolan. [More]
Maintaining healthy weight may be key to prevent MGUS progression to multiple myeloma

Maintaining healthy weight may be key to prevent MGUS progression to multiple myeloma

New research shows that excess weight increases the risk that a benign blood disorder will progress into multiple myeloma, a cancer of the blood. [More]
Implementation of large-scale genomic tumor profiling viable but faces several challenges

Implementation of large-scale genomic tumor profiling viable but faces several challenges

Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible in a broad population of adult and pediatric patients with many different types of cancer, and that some patients can benefit by receiving precision drugs targeted to their tumors' mutations or being enrolled in clinical trials. [More]
BUSM researchers show how MRI can effectively identify bone marrow cancer in experimental model

BUSM researchers show how MRI can effectively identify bone marrow cancer in experimental model

For the first time, researchers have shown that using Magnetic Resonance Imaging (MRI) can effectively identify bone marrow cancer (myelofibrosis) in an experimental model. [More]
Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Scientists uncover how common Epstein-Barr virus causes blood cancer in adults and children

Scientists at the University of Sussex, trying to uncover how the common Epstein-Barr virus causes blood cancer in adults and children, have discovered how the virus takes control of two genes involved in cancer development so it can switch them on or off. [More]
DKMS teams up with football clubs to raise awareness of blood stem cell donation

DKMS teams up with football clubs to raise awareness of blood stem cell donation

Blood cancer charity DKMS is teaming up with football clubs up and down the country in a bid to raise awareness of blood stem cell donation and to register donors. Football Vs Blood Cancer is a new campaign being run by DKMS following support from clubs such as Everton. [More]
Swedish researchers develop new, low-cost method to examine individual leukemia cells

Swedish researchers develop new, low-cost method to examine individual leukemia cells

Leukemia is a disease in which each cell can exhibit different genetic traits, and now Swedish researchers have found a cheap way to examine the individual cells. Reported in Nature Communications, the breakthrough could transform leukemia treatment. [More]
Study finds new therapeutic target to prevent progression of rare blood cancer

Study finds new therapeutic target to prevent progression of rare blood cancer

In a laboratory study, Upstate Medical University researcher Golam Mohi, Ph.D., his graduate student Yue Yang, and colleagues, have found that the loss of gene EZH2 promotes the development of Myelofibrosis (MF) in mice. [More]
High out-of-pocket costs may delay Medicare patients' access to novel targeted treatment for cancer

High out-of-pocket costs may delay Medicare patients' access to novel targeted treatment for cancer

Significant out-of-pocket costs that cancer patients can face before Medicare insurance drug benefits kick in may delay the patients' treatment with a novel class of targeted therapies, according to a University of North Carolina Lineberger Comprehensive Cancer Center-led study. [More]
Antibody drug offers new therapeutic approach for treating AML

Antibody drug offers new therapeutic approach for treating AML

An antibody drug that targets a surface marker on cancer stem cells could offer a promising new therapeutic approach for treating acute myeloid leukemia (AML), a form of blood cancer that affects an estimated 50,000 people in Saudi Arabia. [More]
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