Blood Sugar News and Research

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Blood sugar concentration, or glucose level, refers to the amount of glucose present in the blood of a human or animal. Normally, in mammals the blood glucose level is maintained at a reference range between about 3.6 and 5.8 mM (mmol/l). It is tightly regulated as a part of metabolic homeostasis.

The Lancet publishes Takeda's TAK-875 Phase 2 data on type 2 diabetes

Phase 2 clinical data of an investigational type 2 diabetes therapy, TAK-875 of Takeda Pharmaceutical Company Limited, were published online first in The Lancet.

27 Feb 2012

Nicotine can contribute to atherosclerosis

Cigarette smoke has long been considered the main risk factor for heart disease. But new research from Brown University in Providence, R.I., shows that nicotine itself, a component of cigarette smoke, can contribute to the disease process by changing cell structure in a way that promotes migration and invasion of the smooth muscle cells that line blood vessels.

24 Feb 2012

Insulin production may persist for decades after onset of type 1 diabetes

Massachusetts General Hospital (MGH) research has found that insulin production may persist for decades after the onset of type 1 diabetes. Beta cell functioning also appears to be preserved in some patients years after apparent loss of pancreatic function. The study results appear in the March issue of Diabetes Care.

22 Feb 2012

IDOM researchers overturn textbook view of liver metabolism

A team led by researchers from the Institute for Diabetes, Obesity and Metabolism (IDOM) at the Perelman School of Medicine, University of Pennsylvania, has overturned a "textbook" view of what the body does after a meal.

22 Feb 2012

DPN similar in prediabetic patients and healthy people

In a reversal of two decades of medical reports, a Mayo Clinic study finds the frequency of nerve damage called diabetic polyneuropathy is similar in prediabetic patients and healthy people. Physicians should seek explanations other than prediabetes for patients who have painful small fiber polyneuropathy, the researchers say.

21 Feb 2012

Corcept receives FDA approval for Korlym to treat endogenous Cushing's syndrome

Today, Korlym (mifepristone) was approved by the U.S. Food and Drug Administration to control high blood sugar levels (hyperglycemia) in adults with endogenous Cushing's syndrome.

18 Feb 2012

BYETTA-basal insulin combination therapy receives EMA CHMP positive opinion

Amylin Pharmaceuticals, Inc. and Eli Lilly and Company today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has issued a positive opinion in the European Union for the expanded use of BYETTA (exenatide twice-daily) as an add-on therapy to basal insulin, with or without metformin and/or Actos (pioglitazone), for the treatment of type 2 diabetes in adults who have not achieved adequate glycemic control with these agents.

17 Feb 2012

Diet exerts a strong influence on heart health

Food is your friend and your biggest foe. A healthy diet sustains us, but a poor diet can raise blood pressure, cholesterol, blood sugar levels and weight and put you at risk for heart disease.

16 Feb 2012

Researchers identify potent regulator of sensitivity to insulin

Researchers at Washington University School of Medicine in St. Louis have identified a potent regulator of sensitivity to insulin, the hormone that controls blood sugar levels. The new findings may help scientists find better treatments for type 2 diabetes, obesity and other health problems caused by the body's inability to properly regulate blood sugar.

16 Feb 2012

Study: Diabetes may begin in the gut

Scientists at Washington University School of Medicine in St. Louis have made a surprising discovery about the origin of diabetes. Their research suggests that problems controlling blood sugar - the hallmark of diabetes - may begin in the intestines.

15 Feb 2012

Healthy, loving relationship is good for the heart

Being involved in a healthy, loving relationship is good for the heart, says Vanderbilt Heart and Vascular Institute cardiologist Julie Damp, M.D.

14 Feb 2012

Switching from calorie-laden beverages to water can help lose weight

Making a simple substitution of water or diet soft drinks for drinks with calories can help people lose 4 to 5 pounds, a new University of North Carolina at Chapel Hill study shows.

14 Feb 2012

Oxygen deprivation disrupts insulin and glucose regulation in rat pups

Premature infants' immature lungs and frequent dips in blood pressure make them especially vulnerable to a condition called hypoxia in which their tissues don't receive enough oxygen, sometimes leading to permanent brain damage. New animal research suggests that a common practice in caring for these babies might in fact exacerbate this condition, increasing the chances for long-term neurological deficits.

14 Feb 2012

ACC: New community-wide collaboration to reduce impact of chronic diseases

A new community-wide collaboration to reduce the impact of chronic disease and empower patients is generating impressive early results, leaders of the Accountable Care Community (ACC) initiative said today. The Akron-based Austen BioInnovation Institute in Akron (ABIA) is leading the initiative with its founding institutional members and more than 60 public and private community partners.

9 Feb 2012

Low-glycemic-index foods can improve dietary habits of people with Type 2 diabetes

A specific goal to eat a set number of daily servings of low-glycemic-index foods can improve dietary habits of people with Type 2 diabetes, according to new research.

9 Feb 2012

First study to examine how changes in fitness and fatness affect heart health

Good news for active adults fighting the battle of the bulge. Exercising and getting fit may protect your heart, even if you have a few extra pounds, according to a study published in the Feb. 14 issue of the Journal of the American College of Cardiology (JACC).

9 Feb 2012

First sign of coronary heart disease in men could be death

The healthy heart movement in recent years has focused largely on heart disease as the No. 1 killer of women. But the same statistic is true for men, and the reality is grim: The first sign that a man has coronary heart disease could be death, says one University of Alabama at Birmingham expert.

8 Feb 2012

Karolinska Institutet to study fundamental causes of diabetes

The Swedish medical university, Karolinska Institutet, has received a grant of 1.6 million Euro from the Stichting af Jochnick Foundation for research into the fundamental causes of diabetes. The grant will make it possible to use unique methods to study how the release of insulin is regulated in living organisms - and this will create new opportunities for developing more effective drugs against diabetes.

7 Feb 2012

Research roundup: Safety-net hospitals stack up well against others

This study compares ER performance at safety-net hospitals (those with a disproportionate share of Medicaid and uninsured patients) to non-safety net hospitals to see if proposed pay-for-performance measures could have a negative impact.

6 Feb 2012

Chronic hyperglycemia may lead to cardiac damage

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health suggests that hyperglycemia (high blood sugar) injures the heart, even in patients without a history of heart disease or diabetes.

3 Feb 2012