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Combination of REGN910 and aflibercept inhibits tumor angiogenesis in animal models

Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, held Nov. 12-16, 2011.

14 Nov 2011

Researchers identify new cancer drug discovery approach

Researchers at the University of California, San Diego School of Medicine and the UC San Diego Moores Cancer Center have identified a new drug discovery approach enabling the destruction of the most highly proliferative tumors.

14 Nov 2011

NovaUCD to showcase 15 new high-tech ventures at annual start-up awards

NovaUCD will showcase 15 new high-tech and knowledge-intensive ventures emerging from University College Dublin (UCD) research programmes during its annual start-up awards evening next week.

13 Nov 2011

Classical DCs associated with protection against atherosclerosis

Atherosclerosis, commonly referred to as "hardening of the arteries," is a major risk factor for heart attack and stroke. The cause of atherosclerosis is not well understood but, for some time, chronic inflammatory immune responses have been implicated in driving disease pathology. Now, a new study, published online on November 10th by Cell Press from the journal Immunity, identifies a type of immune cell that is not associated with promoting disease, but with protection against atherosclerosis.

11 Nov 2011

Drug effectively combats obesity in “couch potato” monkeys” Study

According a new study an experimental anti-cancer drug could help fight obesity. The drug chokes off the blood supply to fat cells and helped obese monkeys slim down in the experiments.

10 Nov 2011

Experimental drug selectively destroys blood supply of fat tissue and decreases body fat

Obese rhesus monkeys lost on average 11 percent of their body weight after four weeks of treatment with an experimental drug that selectively destroys the blood supply of fat tissue, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports in Science Translational Medicine.

10 Nov 2011

Positive results from InSeal's intravascular large bore puncture closure device trial

InSeal Medical Ltd., developer of percutaneous vascular closure devices for large bore punctures, today announced the successful treatment of three patients with its investigational intravascular large bore puncture closure device.

10 Nov 2011

Insulin resistance associated with cortical atrophy and brain dysfunction

Many complications of diabetes, including kidney disease, foot problems and vision problems are generally well recognized. But the disease's impact on the brain is often overlooked.

9 Nov 2011

EI-IC bypass surgery does not lower risk of stroke recurrence in patients with TIA

A surgical procedure aimed at bypassing a blocked artery that supplies blood to the brain did not lower the subsequent stroke rate after 2 years in people who previously had a minor stroke, compared to those who did not have the surgery.

9 Nov 2011

Johns Hopkins researchers unravel how breast cancer metastasizes

The spread of breast cancer is responsible for more than 90 percent of breast cancer deaths. Now, the process by which it spreads—or metastasizes—has been unraveled by researchers at Johns Hopkins. Reporting in two papers, the researchers have discovered the switch that enables breast cancer cells to travel to and be received in the lungs.

9 Nov 2011

BioTime third quarter revenue increases 40% to $1.1 million

BioTime, Inc., a biotechnology company that develops and markets products in the field of regenerative medicine, today reported financial results for the third quarter and nine months ended September 30, 2011 and highlighted recent corporate accomplishments.

9 Nov 2011

RWJF announces recipients of 2011 Community Health Leaders Award

The Robert Wood Johnson Foundation is proud to announce today the recipients of its 2011 Community Health Leaders Award, honoring 10 individuals who have overcome daunting odds to improve the health and quality of life for disadvantaged or underserved communities across the country.

9 Nov 2011

Brain bypass still plays a critical role in management of selected neurovascular disorders

A microsurgical procedure that has lost some ground to advances in endovascular therapy still plays a critical role in the management of selected neurovascular disorders, according to a University Hospitals Case Medical Center neurosurgeon who performs the procedure.

8 Nov 2011

New breakthrough facelifting technique

In their November issue, the Aesthetic Surgery Journal published a new breakthrough facelifting technique which gives superior results with fewer complications than current techniques in practice. The pioneer of this new Minimal Access Deep Plane Extended Vertical "MADE" Facelift is NY Facial Plastic and Reconstructive Surgeon, Dr. Andrew Jacono.

7 Nov 2011

Bike riding cuts off blood flow to men's genitals

Is it just an urban myth, or can long-term bike riding cause sexual dysfunction in men? Previous studies have not shed much light on the question, says Dr. Craig Niederberger, professor and head of urology at the University of Illinois at Chicago College of Medicine, because they have not shown whether bike riding actually cuts off blood flow to men's genitals.

7 Nov 2011

Anti-TNFs, methotrexate may reduce risk of cardiovascular disease in people with RA

Taking methotrexate or anti-TNFs is associated with a reduction in risk of cardiovascular disease in people with rheumatoid arthritis, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago.

7 Nov 2011

HHS scientists to share recent rheumatology findings at 75th ACR annual meeting

Hospital for Special Surgery physician-scientists who focus on arthritis, lupus, vasculitis and related conditions are traveling from New York City to Chicago this week to share their recent findings at the 75th Annual Scientific Meeting of the American College of Rheumatology.

7 Nov 2011