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Research findings pave way to effective strategies for treatment of visceral leishmaniasis

Research findings pave way to effective strategies for treatment of visceral leishmaniasis

A study shows that stimulating the production of interleukin-17A (IL-17A), one of the cytokines released by cells of the immune system, can be an effective strategy for the treatment of visceral leishmaniasis, considered one of the six most important parasitic diseases affecting humans. [More]
Protein complex could play key role in natural development of stem cells into healthy blood cells

Protein complex could play key role in natural development of stem cells into healthy blood cells

A group of proteins best known for helping to activate all mammalian genes has been found to play a particularly commanding role in the natural development of specialized stem cells into healthy blood cells, a process known as hematopoiesis. [More]
Researchers discover novel pathway for immune recovery following bone-marrow transplantation

Researchers discover novel pathway for immune recovery following bone-marrow transplantation

New research has shown how a cell surface molecule, Lymphotoxin β receptor, controls entry of T-cells into the thymus; and as such presents an opportunity to understanding why cancer patients who undergo bone-marrow transplant are slow to recover their immune system. [More]
New imaging technique may help detect amyloid-related heart failure

New imaging technique may help detect amyloid-related heart failure

A type of heart failure caused by a build-up of amyloid can be accurately diagnosed and prognosticated with an imaging technique, eliminating the need for a biopsy, according to a multicenter study led by researchers at Columbia University Medical Center. [More]
Assigning barcode to stem cells makes it possible to monitor large blood cell populations

Assigning barcode to stem cells makes it possible to monitor large blood cell populations

By assigning a barcode to stem cells, researchers at Lund University in Sweden have made it possible to monitor large blood cell populations as well as individual blood cells, and study the changes over time. [More]
Tendon transfer for quadriplegics greatly underused, article reveals

Tendon transfer for quadriplegics greatly underused, article reveals

A surgery for quadriplegics called tendon transfer can significantly improve hand and elbow function, but the procedure is greatly underused, according to an article in the journal Hand Clinics by Loyola Medicine hand surgeon Michael S. Bednar, MD, FAAOS. [More]
Researchers investigate link between diet, obesity-linked Type 2 diabetes, and spinal disc degeneration

Researchers investigate link between diet, obesity-linked Type 2 diabetes, and spinal disc degeneration

Can a diet high in processed fat and sugar and Type 2 diabetes cause degeneration of intervertebral discs in the spine? If so, what is happening, and can it be prevented? As part of an ongoing collaboration between Rensselaer Polytechnic Institute and the Icahn School of Medicine at Mount Sinai - a partnership that draws upon the expertise of both schools to address significant health problems - researchers hope to answer those questions by investigating the link between diet, obesity-linked Type 2 diabetes, and intervertebral disc degeneration. [More]
TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

The part of the jawbone containing tooth sockets is known as alveolar bone, and its loss over time or following dental disease may ultimately result in tooth loss. [More]
Research finding opens door to new treatment options for inflammatory rheumatism

Research finding opens door to new treatment options for inflammatory rheumatism

Enthesitis, inflammation of tendons where they attach to the bone, is a common medical problem which underlies various forms of inflammatory rheumatism. [More]
Soluble corn fiber can help build and retain calcium in bone during adolescence and post-menopause

Soluble corn fiber can help build and retain calcium in bone during adolescence and post-menopause

Supplementing with soluble corn fiber at two critical times in a woman's life - adolescence and post-menopause - can help build and retain calcium in bone, according to new research from Purdue University. [More]
Study looks at ways to reduce prescription drugs linked to fracture risk among older adults

Study looks at ways to reduce prescription drugs linked to fracture risk among older adults

Fragility fractures -- those that occur at standing height -- are a significant source of sickness and death among the elderly population in the United States. They are also associated with annual direct costs of over $16 billion. [More]
Penn researchers uncover strategy to reverse effects of dyskeratosis congenita

Penn researchers uncover strategy to reverse effects of dyskeratosis congenita

Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no cure. [More]
Tulane professor receives three-year grant to improve survival of mesenchymal stem cells

Tulane professor receives three-year grant to improve survival of mesenchymal stem cells

Kim O'Connor, a professor in Tulane University's Department of Chemical and Biomolecular Engineering, received a three-year $599,638 grant from the National Science Foundation to study ways to improve the survival of mesenchymal stem cells once they are implanted in patients. [More]
Research opens door to new class of treatments for gum disease

Research opens door to new class of treatments for gum disease

If you hate going to the dentist, here's some good news. New research published online in The FASEB Journal, shows that melanocortin agonism may effectively control the inflammation that often occurs in gum tissue, which when unchecked, ultimately accelerates tooth and bone loss. [More]
Scientists discover way to visualize function of bone-resorbing cells in living mice

Scientists discover way to visualize function of bone-resorbing cells in living mice

Researchers of Osaka University have discovered a way to visualize sites where bone-resorbing cells (osteoclasts) were in the process of resorbing bone in living mice. [More]
New test holds potential to revolutionise diagnosis of childhood leukaemia

New test holds potential to revolutionise diagnosis of childhood leukaemia

Researchers at The University of Manchester have unlocked the potential of a new test which could revolutionise the way doctors diagnose and monitor a common childhood leukaemia. [More]
MSU scientists show how special genes stay open to fight against infections

MSU scientists show how special genes stay open to fight against infections

A new discovery at Michigan State University has revealed how special genes stay open for business, helping diagram a mechanism that plays a key role in fighting inflammation and infections. [More]
Stem cells derived from bone marrow provide better quality of life to transplant patients

Stem cells derived from bone marrow provide better quality of life to transplant patients

A large, nationwide study published in the journal JAMA Oncology found that people who received transplants of cells collected from a donor's bone marrow the original source for blood stem cell transplants, developed decades ago had better self-reported psychological well-being, experienced fewer symptoms of a common post-transplant side effect called graft-vs.-host disease and were more likely to be back at work five years after transplantation than those whose transplanted cells were taken from the donor's bloodstream. [More]
German scientists develop new approach to prevent GvHD after bone marrow transplants

German scientists develop new approach to prevent GvHD after bone marrow transplants

Scientists in Germany have developed a new approach that may prevent leukemia and lymphoma patients from developing graft-versus-host disease (GvHD) after therapeutic bone marrow transplants. [More]
Researchers chart microbial ecology of the mouth at all stages of gum disease progression

Researchers chart microbial ecology of the mouth at all stages of gum disease progression

Gingivitis, a common and mild form of gum disease can progress to periodontitis, a more serious infection that damages the soft tissue of the gums and sometimes even destroys the bone supporting the teeth. [More]
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