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Cardiff scientists make breakthrough asthma discovery

Cardiff scientists make breakthrough asthma discovery

Cardiff University scientists have for the first time identified the potential root cause of asthma and an existing drug that offers a new treatment. [More]
Cardiff scientists identify potential root cause of asthma and highlight new treatment option

Cardiff scientists identify potential root cause of asthma and highlight new treatment option

Cardiff University scientists have for the first time identified the potential root cause of asthma and an existing drug that offers a new treatment. [More]
Stem cell treatment repairs birth defect, provides facial regeneration for people suffering traumatic injury

Stem cell treatment repairs birth defect, provides facial regeneration for people suffering traumatic injury

Researchers have pinpointed a primary cause of a rare skull disorder in infants, and the discovery could help wounded soldiers, car-wreck victims and other patients recover from disfiguring facial injuries. [More]
Adseverin protein plays key role in bone loss associated with osteoinflammatory disease

Adseverin protein plays key role in bone loss associated with osteoinflammatory disease

Adseverin, a protein found in the body, has been identified as the key driver behind the bone loss associated with the world's most common inflammatory disease: gum disease, or periodontitis. [More]
Researchers explore evolution of eardrums

Researchers explore evolution of eardrums

Researchers at the RIKEN Evolutionary Morphology Laboratory and the University of Tokyo in Japan have determined that the eardrum evolved independently in mammals and diapsids--the taxonomic group that includes reptiles and birds. Published in Nature Communications, the work shows that the mammalian eardrum depends on lower jaw formation, while that of diapsids develops from the upper jaw. [More]
Data from pacritinib Phase 3 PERSIST-1 trial in patients with myelofibrosis to be highlighted at ASCO

Data from pacritinib Phase 3 PERSIST-1 trial in patients with myelofibrosis to be highlighted at ASCO

CTI BioPharma Corp. and Baxter International Inc. today announced that data from the randomized Phase 3 PERSIST-1 trial evaluating the investigational agent pacritinib in patients with myelofibrosis will be highlighted in a late-breaking oral presentation at the upcoming American Society of Clinical Oncology 2015 Meeting (May 29-June 2, 2015 in Chicago, Ill). [More]
Spanish scientists find apatite bioceramics from shark teeth for implants

Spanish scientists find apatite bioceramics from shark teeth for implants

Researchers from the BIOCAPS Area of 'Biomaterials, tissue engineering and regenerative medicine' have managed to obtain bioceramics from shark teeth, which have already tested applications in the regeneration of bone tissue, particularly in the fields of traumatology and odontology. [More]
UVA research identifies new role of immune system in Rett syndrome

UVA research identifies new role of immune system in Rett syndrome

The immune system is designed to protect us from disease. But what if it was malfunctioning? Would it make a disease worse? That appears to be the case with Rett syndrome, a neurodevelopmental disorder, and possibly in other neurological disorders as well, new research from the University of Virginia School of Medicine has found. [More]
Rocket carrying Reinnervate's Alvetex Scaffold blasts into Space to find better treatments for bone loss

Rocket carrying Reinnervate's Alvetex Scaffold blasts into Space to find better treatments for bone loss

Market leading 3D cell culture company Reinnervate Ltd, part of the ReproCELL group, today announced that a rocket carrying its Alvetex Scaffold technology blasted into Space this week. Alvetex will be used in experiments on board the International Space Station. [More]
Upsher-Smith presents favorable data from PREVAIL OLE study of Qudexy XR capsules

Upsher-Smith presents favorable data from PREVAIL OLE study of Qudexy XR capsules

Upsher-Smith Laboratories, Inc. presented data from a 52-week, open-label extension study (PREVAIL OLE) showing that Qudexy XR (topiramate) extended-release capsules offered a long-term adjunctive treatment option with a favorable tolerability profile for a high proportion of patients with refractory partial-onset seizures (POS). [More]
BrainStorm presents positive results from NurOwn phase 2a study in ALS at AAN annual meeting

BrainStorm presents positive results from NurOwn phase 2a study in ALS at AAN annual meeting

BrainStorm Cell Therapeutics Inc., a leading developer of adult stem cell technologies for neurodegenerative diseases, is presenting results from its phase 2a study of NurOwn in amyotrophic lateral sclerosis (ALS) at a poster session today at the American Academy of Neurology annual meeting, taking place in Washington D.C. [More]
CML guidelines highlight need for TKI switch timing, choice

CML guidelines highlight need for TKI switch timing, choice

A review of the European LeukemiaNet guidelines on the care of patients with chronic myeloid leukaemia highlights the need for research into the timing and use of second-line and third-line tyrosine kinase inhibitors. [More]
HSCT increases fracture risk

HSCT increases fracture risk

Fracture incidence is greatly increased in individuals who undergo haematopoietic stem cell transplantation compared with the general US population, research shows. [More]
May issue of Red Journal focuses on role of radiation therapy in current lymphoma treatment

May issue of Red Journal focuses on role of radiation therapy in current lymphoma treatment

The "Radiation and the Modern Management of Lymphoma" issue (May 1, 2015) of the International Journal of Radiation Oncology • Biology • Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology, is focused on the integral role of radiation therapy in current lymphoma treatment. [More]
Obesity in African-American men increases prostate cancer risk

Obesity in African-American men increases prostate cancer risk

Obesity has a profoundly different effect on prostate cancer risk in African-American as compared to non-Hispanic white men. Obesity in black men substantially increases the risk of low- and high-grade prostate cancer, while obesity in white men moderately reduces the risk of low-grade cancer and only slightly increases the risk of high-grade cancer, according to the first large, prospective study to examine how race and obesity jointly affect prostate cancer risk. [More]
Moirai Orthopaedics receives FDA approval for IDE application to initiate clinical study of PIR System

Moirai Orthopaedics receives FDA approval for IDE application to initiate clinical study of PIR System

Moirai Orthopaedics, L.L.C., an orthopaedic implant development company based in Metairie, Louisiana, is pleased to announce it has received approval from the US Food and Drug Administration for its Investigational Device Exemption (IDE) application to initiate clinical study of the company's Pyrocarbon Implant Replacement (PIR) System. [More]
Scientists find link between higher muscle mass and healthier bone development in children

Scientists find link between higher muscle mass and healthier bone development in children

Scientists at the University of Southampton have shown that higher muscle mass is strongly linked with healthier bone development in children. [More]
U-M researchers make major breakthrough in diagnosing, treating prostate cancer

U-M researchers make major breakthrough in diagnosing, treating prostate cancer

University of Michigan researchers have discovered a biomarker that may be a potentially important breakthrough in diagnosing and treating prostate cancer. [More]
Aeterna Zentaris plans to conduct Macrilen Phase 3 clinical study for AGHD

Aeterna Zentaris plans to conduct Macrilen Phase 3 clinical study for AGHD

Aeterna Zentaris Inc. today announced plans to conduct a new, confirmatory Phase 3 clinical study to demonstrate the efficacy of Macrilen (macimorelin), a novel orally-active ghrelin agonist for use in evaluating adult growth hormone deficiency ("AGHD"), as well as a dedicated thorough QT study to evaluate the effect of Macrilen on myocardial repolarization. [More]
Osteocyte study in space: Researchers to analyze effects of microgravity on osteocyte cultures

Osteocyte study in space: Researchers to analyze effects of microgravity on osteocyte cultures

Researchers may be "excyted" to learn that osteocyte cultures are headed to the International Space Station this spring for the first time. With their delivery on the next SpaceX commercial resupply services mission this month, the Osteocytes and mechano-transduction (Osteo-4) investigation team will analyze the effects of microgravity on this type of bone cell. [More]
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