Bone Marrow News and Research RSS Feed - Bone Marrow News and Research

Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.
Experimental T-cell therapy shows promise in preventing AML relapse

Experimental T-cell therapy shows promise in preventing AML relapse

Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells. [More]
Simple, coordinated approach can improve chances of survival for high-risk AML patients

Simple, coordinated approach can improve chances of survival for high-risk AML patients

New research shows that quickly identifying patients with high-risk acute myeloid leukemia (AML), and speeding the process to find them a stem cell donor and performing the transplant earlier, can significantly improve their chances of surviving for at least two years after diagnosis without a relapse. [More]
Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Patients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia, sometimes years after completion of treatment, due to a genetic mutation leading to secondary malignancies known as therapy-related myeloid neoplasms (t-MNs). [More]
Scientists discover molecular link between rare childhood genetic disease and major cancer gene

Scientists discover molecular link between rare childhood genetic disease and major cancer gene

A team of researchers led by a University of Rhode Island scientist has discovered an important molecular link between a rare childhood genetic disease, Fanconi anemia, and a major cancer gene called PTEN. [More]
TGen and City of Hope collaborate to accelerate precision medicine research

TGen and City of Hope collaborate to accelerate precision medicine research

City of Hope, a world-renowned independent research and cancer and diabetes treatment center, and Translational Genomics Research Institute, a leading biomedical research institute, announced today that they have formed an alliance to make precision medicine a reality for patients. [More]
Scientists identify cell-surface receptor for progranulin

Scientists identify cell-surface receptor for progranulin

Progranulin is produced and secreted by most cells in the body. From skin to immune cells, brain to bone marrow cells, progranulin plays a key role in maintaining normal cellular function. [More]
Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

Preventative strategy in stem cell transplant recipients may help thwart C. diff infections

It may be possible to safely prevent one of the most common - and costly to treat - infections contracted by hospitalized patients undergoing bone marrow transplantation for the treatment of blood cancers, according to a study from the Abramson Cancer Center at the University of Pennsylvania. [More]
Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

Researchers reveal mechanism for side effects of drug used for treating hematological malignancies

A team of Japanese researchers revealed the mechanism for side effects such as fever and bone pain caused by G-CSF, which is widely used for peripheral blood hematopoietic stem cell harvesting (PBSCH). [More]
Cancer gene mutations can predict response to less intensive treatment in AML patients

Cancer gene mutations can predict response to less intensive treatment in AML patients

Patients with the most lethal form of acute myeloid leukemia (AML) - based on genetic profiles of their cancers - typically survive for only four to six months after diagnosis, even with aggressive chemotherapy. [More]
HSCI researchers use color tagging system to track development of blood stem cells

HSCI researchers use color tagging system to track development of blood stem cells

Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of veins, arteries, and capillaries back to their parent stem cell in the marrow. [More]
New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells

A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's Stem Cell Research Program. [More]
Maintaining healthy weight may be key to prevent MGUS progression to multiple myeloma

Maintaining healthy weight may be key to prevent MGUS progression to multiple myeloma

New research shows that excess weight increases the risk that a benign blood disorder will progress into multiple myeloma, a cancer of the blood. [More]
New research helps explain possible mechanism for recurrence of breast cancer

New research helps explain possible mechanism for recurrence of breast cancer

In October, we mourned those who died of breast cancer and celebrated all of the women (and men) who have survived. What many of those survivors worry about, though, is that their breast cancer may come back. [More]
BUSM researchers show how MRI can effectively identify bone marrow cancer in experimental model

BUSM researchers show how MRI can effectively identify bone marrow cancer in experimental model

For the first time, researchers have shown that using Magnetic Resonance Imaging (MRI) can effectively identify bone marrow cancer (myelofibrosis) in an experimental model. [More]
New research uncovers role of spleen in long-term anxiety following psychological stress

New research uncovers role of spleen in long-term anxiety following psychological stress

Scientists are uncovering clues to what might be unfolding in the relationship between the brain and immune system in those who suffer from long-term repercussions of stress. [More]
CHLA researchers receive TRP grant to study new way of combating relapsed ALL

CHLA researchers receive TRP grant to study new way of combating relapsed ALL

Yong-Mi Kim, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles, has been awarded a 3 year translational research program grant from the Leukemia & Lymphoma Society to study a novel approach to eradicating minimal residual disease in patients with acute lymphoblastic leukemia (ALL). [More]
SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

SMU virologist receives NCI grant to advance research into how certain viruses cause cancers

SMU virologist and cancer researcher Robert L. Harrod has been awarded a $436,500 grant from the National Cancer Institute to further his lab's research into how certain viruses cause cancers in humans. [More]
ASH partners with other organizations to address knowledge gaps in AML care

ASH partners with other organizations to address knowledge gaps in AML care

The American Society of Hematology has partnered with several organizations on independent educational programming designed to help address knowledge gaps in the diagnosis and treatment of acute myeloid leukemia (AML). [More]
Stem cell therapy appears to dampen the body's neuroinflammatory response to trauma, preserve brain tissue

Stem cell therapy appears to dampen the body's neuroinflammatory response to trauma, preserve brain tissue

Results of a cellular therapy clinical trial for traumatic brain injury (TBI) using a patient's own stem cells showed that the therapy appears to dampen the body's neuroinflammatory response to trauma and preserve brain tissue, according to researchers at The University of Texas Health Science Center at Houston. [More]
Scientists discover novel therapeutic target and treatment strategy for acute myeloid leukemia

Scientists discover novel therapeutic target and treatment strategy for acute myeloid leukemia

University of Hawai'i Cancer Center researchers discovered a novel therapeutic target and treatment strategy for acute myeloid leukemia, a cancer of the blood and bone marrow that normally requires prompt and aggressive treatment. [More]
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