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Endurance running training increases bone density

Endurance running training increases bone density

Spanish researchers have analysed the effect of endurance running training on the stiffness index, a variable that is directly related to bone quality. The results confirm that the greater the race distance that is trained, the better; this can be used, therefore, to prevent the progressive decline in bone mineral density that occurs with age. [More]
ADHD stimulant drugs may lower bone density in children and adolescents

ADHD stimulant drugs may lower bone density in children and adolescents

Children and teenagers who take stimulant drugs to treat attention-deficit hyperactivity disorder (ADHD) may have lower bone density than their peers who do not take these medications, a new study finds. [More]
Investigational drug abaloparatide-SC may help increase bone mineral density in postmenopausal women

Investigational drug abaloparatide-SC may help increase bone mineral density in postmenopausal women

The investigational drug abaloparatide-SC (subcutaneous) may help increase bone mineral density in postmenopausal women and reduce their risk of fracture, new industry-sponsored research suggests. The results of the subgroup analysis within the ACTIVE clinical trial will be presented Friday, April 1, at ENDO 2016, the annual meeting of the Endocrine Society in Boston. [More]
Pediatric researchers find gene variants that can strongly increase bone strength in girls

Pediatric researchers find gene variants that can strongly increase bone strength in girls

Pediatric researchers have found that rare genetic changes strongly increase the likelihood that a child will have higher bone density, but only in girls. [More]
Fertility problems put men at increased risk of metabolic diseases

Fertility problems put men at increased risk of metabolic diseases

Men with fertility problems are at risk of metabolic diseases as they age, according to work being presented at the European Association of Urology conference in Munich [More]
Higher BMI in mothers linked with lower vitamin D levels in babies

Higher BMI in mothers linked with lower vitamin D levels in babies

Does a newborn's vitamin D level relate to the mother's weight during pregnancy? Results from a study published in PLOS ONE (Public Library of Science) provides ample evidence that yes, higher body mass index (BMI) in mothers is associated with lower vitamin D levels in their babies. [More]
Kids who take ADHD medications show decreased bone density

Kids who take ADHD medications show decreased bone density

Children and adolescents who take medication for attention-deficit hyperactivity disorder (ADHD) show decreased bone density, according to a large cross-sectional study presented today at the 2016 Annual Meeting of the American Academy of Orthopaedic Surgeons. [More]
Osteoporosis drugs linked to unusual fractures of the femur

Osteoporosis drugs linked to unusual fractures of the femur

Osteoporosis drugs have significantly reduced the risk of bone fractures for millions of people, but also have been linked to unusual fractures of the femur (thigh bone). [More]
Surprising bone health findings in women with restless legs syndrome

Surprising bone health findings in women with restless legs syndrome

Contrary to the researchers' expectations, a study shows that women with restless legs syndrome have increased bone mineral density in some sites. [More]
Low-sodium intake has little impact on bone health in postmenopausal women

Low-sodium intake has little impact on bone health in postmenopausal women

A low-salt diet does not necessarily translate to stronger bones in postmenopausal women, physician-scientists report. [More]
Romosozumab for postmenopausal women with osteoporosis meets co-primary endpoints in Phase 3 study

Romosozumab for postmenopausal women with osteoporosis meets co-primary endpoints in Phase 3 study

Amgen and UCB today announced top-line results from the Phase 3 placebo-controlled FRActure study in postmenopausal woMen with ostEoporosis (FRAME). [More]
Intestinal microbiota necessary for optimum postnatal growth

Intestinal microbiota necessary for optimum postnatal growth

The intestinal microbiota is necessary to ensure optimum postnatal growth and contributes to determining the size of adult individuals, notably in the event of undernutrition. [More]
Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter and year ended December 31, 2015. [More]
Exercise-associated bone loading during adolescence, young adulthood benefits bone density in adulthood

Exercise-associated bone loading during adolescence, young adulthood benefits bone density in adulthood

Men have many reasons to add high-impact and resistance training to their exercise regimens; these reasons include building muscle and shedding fat. Now a University of Missouri researcher has determined another significant benefit to these activities: building bone mass. [More]
Certain genes could lead to stress fracture injuries

Certain genes could lead to stress fracture injuries

In a paper published in The Official Journal of the International Purine Club University of Liverpool researchers have successfully identified how certain genes can contribute towards a person's susceptibility to stress fracture injuries. This research provides a platform for further research into providing a personalised health approach to this common sports injury. [More]
Bone loss linked with ALL therapy occurs during first month of treatment

Bone loss linked with ALL therapy occurs during first month of treatment

Investigators at Children's Hospital Los Angeles have found that significant bone loss - a side effect of chemotherapy for acute lymphoblastic leukemia (ALL) - occurs during the first month of treatment, far earlier than previously assumed. Results of the study will be available online February 4, in advance of publication in the journal Bone. [More]
AbbVie announces initiation of first Elagolix Phase 3 study in patients with uterine fibroid

AbbVie announces initiation of first Elagolix Phase 3 study in patients with uterine fibroid

AbbVie, in cooperation with Neurocrine Biosciences, Inc., today announced the initiation of the first of two planned Phase 3 clinical studies evaluating the safety and efficacy of Elagolix alone or in combination with add-back therapy compared to placebo. [More]
Parathyroid hormone may mediate antihypertensive fracture risk

Parathyroid hormone may mediate antihypertensive fracture risk

Parathyroid hormone levels may be elevated by use of some antihypertensive agents but reduced by others, analysis of the Multi-Ethnic Study of Atherosclerosis suggests. [More]
Active individuals may need to maintain higher vitamin D levels to reduce risk of stress fractures

Active individuals may need to maintain higher vitamin D levels to reduce risk of stress fractures

Vitamin D plays a crucial role in ensuring appropriate bone density. Active individuals who enjoy participating in higher impact activities may need to maintain higher vitamin D levels to reduce their risk of stress fractures, report investigators in The Journal of Foot & Ankle Surgery. [More]
Adjuvant denosumab improves disease-free survival for postmenopausal women with early-stage, HR+ breast cancer

Adjuvant denosumab improves disease-free survival for postmenopausal women with early-stage, HR+ breast cancer

Adding denosumab to adjuvant aromatase inhibitor therapy improved disease-free survival for postmenopausal patients with early-stage, hormone receptor (HR)-positive breast cancer, according to results from the phase III ABCSG-18 clinical trial presented at the 2015 San Antonio Breast Cancer Symposium, held Dec. 8-12. [More]
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