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New clinical trial focuses on respiratory drug ambroxol for treatment of Parkinson's disease

New clinical trial focuses on respiratory drug ambroxol for treatment of Parkinson's disease

A medication approved to treat various respiratory diseases and that has demonstrated neuroprotective effects in preclinical studies is the focus of a new clinical trial for Parkinson's disease. [More]
Lamin nucleoskeleton disordered in Alzheimer's

Lamin nucleoskeleton disordered in Alzheimer's

Brain cell death in Alzheimer's disease is linked to disruption of a skeleton that surrounds the nucleus of the cells, a researcher in the School of Medicine at The University of Texas Health Science Center at San Antonio said. [More]
Graphene-based electrodes could be safely implanted in the brain

Graphene-based electrodes could be safely implanted in the brain

Researchers have successfully demonstrated how it is possible to interface graphene - a two-dimensional form of carbon - with neurons, or nerve cells, while maintaining the integrity of these vital cells. The work may be used to build graphene-based electrodes that can safely be implanted in the brain, offering promise for the restoration of sensory functions for amputee or paralysed patients, or for individuals with motor disorders such as epilepsy or Parkinson's disease. [More]
Scientists pin down molecular process linked to schizophrenia origin

Scientists pin down molecular process linked to schizophrenia origin

For the first time, researchers have managed to home in on a molecular process in the brain that contributes to the development of schizophrenia. [More]
New sites opened across the South West for Alzheimer’s disease clinical trial

New sites opened across the South West for Alzheimer’s disease clinical trial

People with Alzheimer’s disease are helping with a ground-breaking government-funded trial but with new sites recently opened in the South West more people are being asked to take part in the study led by academics from the Universities of Bristol, Cambridge, Queen’s University Belfast and University College London, and hosted by North Bristol NHS Trust. [More]
3-D recordings of nematode brains may help understand how neurons coordinate action and perception

3-D recordings of nematode brains may help understand how neurons coordinate action and perception

Princeton University researchers have captured among the first recordings of neural activity in nearly the entire brain of a free-moving animal. The three-dimensional recordings could provide scientists with a better understanding of how neurons coordinate action and perception in animals. [More]
YAP protein appears to play vital role in helping control inflammation inside the brain

YAP protein appears to play vital role in helping control inflammation inside the brain

Inside the brain, a protein called YAP, best known for its ability to help right-size our developing hearts and livers, appears to have the different but equally important task of helping control inflammation. [More]
Study: Brain cell death may trigger multiple sclerosis

Study: Brain cell death may trigger multiple sclerosis

Multiple sclerosis (MS) may be triggered by the death of brain cells that make myelin, the insulation around nerve fibers, according to research on a novel mouse model developed by scientists from the University of Chicago and Northwestern Medicine. The death of these cells initiates an autoimmune response against myelin, the main characteristic of the disease, which leads to MS-like symptoms in mice. [More]
Researchers trace origins of early abnormal brain overgrowth in ASD

Researchers trace origins of early abnormal brain overgrowth in ASD

Further underscoring the prenatal origins of Autism Spectrum Disorder (ASD), researchers at University of California, San Diego School of Medicine describe for the first time how abnormal gene activity in cell cycle networks that are known to control brain cell production may underlie abnormal early brain growth in the disorder. [More]
Air evacuations may pose significant added risk to patients with traumatic brain injury

Air evacuations may pose significant added risk to patients with traumatic brain injury

Over the past 15 years, more than 330,000 U.S. soldiers have suffered a traumatic brain injury (TBI). It is one of the leading causes of death and disability connected to the country's recent conflicts in Afghanistan and Iraq. Many of these patients were evacuated by air from these countries to Europe and the U.S. for further treatment. In general, these patients were flown quickly to hospitals outside the battle zone, where more extensive treatment was available. [More]
Researchers find lower levels of omega-3 fatty acids in people with bipolar disorder

Researchers find lower levels of omega-3 fatty acids in people with bipolar disorder

People with bipolar disorder have lower levels of certain omega-3 fatty acids that cross the blood-brain barrier compared to those who do not, according to researchers from Penn State College of Medicine and the National Institutes of Health. The finding could have implications for dietary interventions for the disorder. [More]
Slower aging reduces degeneration related to Parkinson's disease

Slower aging reduces degeneration related to Parkinson's disease

Humans have long sought to reduce the effects of aging. Now, there may be another reason to continue searching for ways to slow the clock--preventing Parkinson's disease. [More]
Study sheds light on mechanism of neuronal activity

Study sheds light on mechanism of neuronal activity

Neurons communicate by passing electrical messages, known as action potentials, between each other. Each neuron has a highly specialized structural region, the axon initial segment (AIS), whose primary role is in the generation and sending of these messages. [More]
Insulin plays a much stronger role in regulating release of dopamine

Insulin plays a much stronger role in regulating release of dopamine

Insulin, the hormone essential to all mammals for controlling blood sugar levels and a feeling of being full after eating, plays a much stronger role than previously known in regulating release of dopamine, a neurotransmitter that helps control the brain's reward and pleasure centers, new studies by researchers at NYU Langone Medical Center show. [More]
Love hormone may enhance pleasure of social interactions, UCI study finds

Love hormone may enhance pleasure of social interactions, UCI study finds

The hormone oxytocin, which has been associated with interpersonal bonding, may enhance the pleasure of social interactions by stimulating production of marijuana-like neurotransmitters in the brain, according to a University of California, Irvine study. [More]
Breakthrough research suggests that female sex hormone may save lives on the battlefield

Breakthrough research suggests that female sex hormone may save lives on the battlefield

Breakthrough research suggests a female sex hormone may be the key to saving lives on the battlefield, where between 2001 and 2011 more than 80 percent of potentially preventable U.S. war injury deaths resulted from blood loss. [More]
Researchers develop methodology to monitor changes in DNA methylation patterns in individual cells

Researchers develop methodology to monitor changes in DNA methylation patterns in individual cells

Whitehead Institute researchers have developed a methodology to monitor changes in DNA methylation over time in individual cells. [More]
Disrupting specific signaling pathway in the brain can cause overeating of high fat foods

Disrupting specific signaling pathway in the brain can cause overeating of high fat foods

Defective signaling in the brain can cause overeating of high fat foods in mice, leading to obesity, according to one of the first research articles published in the new open access journal Heliyon. [More]
USF study shows spleen may be a new target for treating stroke-induced chronic inflammation

USF study shows spleen may be a new target for treating stroke-induced chronic inflammation

Stroke injures the brain, but a new University of South Florida study indicates an abdominal organ that plays a vital role in immune function, the spleen, may be a target for treating stroke-induced chronic inflammation leading to further brain cell death. [More]
Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Diabetes may be linked to the buildup of tangles or tau in the brain, separate from Alzheimer's disease, according to a new study published in the September 2, 2015, online version of Neurology, the medical journal of the American Academy of Neurology. [More]
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