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Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

Scientists discover why cerebellar granule cell neurons in A-T patients fail to repair DNA damage

A team of scientists, led by Stuart Lipton, M.D., Ph.D., professor and director of the Neuroscience and Aging Research Center at Sanford-Burnham Medical Research Institute, recently discovered why cerebellar granule cell neurons in patients suffering from ataxia-telangiectasia (A-T) were unable to repair DNA damage and thus died. [More]
Stem cell research opens doors to potential new treatments for bipolar disorder

Stem cell research opens doors to potential new treatments for bipolar disorder

What makes a person bipolar, prone to manic highs and deep, depressed lows? Why does bipolar disorder run so strongly in families, even though no single gene is to blame? And why is it so hard to find new treatments for a condition that affects 200 million people worldwide? [More]
NeuroVive Pharmaceutical initiates research collaboration with A1M Pharma

NeuroVive Pharmaceutical initiates research collaboration with A1M Pharma

NeuroVive Pharmaceutical AB (publ) and A1M Pharma AB (publ) have announced that the two companies are initiating a research collaboration in mitochondrial medicine. The partnership is governed by a collaboration agreement signed on 21 March 2014. [More]
New treatment could halt progression of dementia

New treatment could halt progression of dementia

Researchers at the University of Texas Medical Branch at Galveston have discovered a way to potentially halt the progression of dementia caused by accumulation of a protein known as tau. [More]
People who develop diabetes in middle age are more likely to have brain cell loss in old age

People who develop diabetes in middle age are more likely to have brain cell loss in old age

People who develop diabetes and high blood pressure in middle age are more likely to have brain cell loss and other damage to the brain, as well as problems with memory and thinking skills, than people who never have diabetes or high blood pressure or who develop it in old age, according to a new study published in the March 19, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. [More]
Researchers discover USP9X gene that sheds new light on mysteries of brain development, disability

Researchers discover USP9X gene that sheds new light on mysteries of brain development, disability

Research from the University of Adelaide has confirmed that a gene linked to intellectual disability is critical to the earliest stages of the development of human brains. [More]
Researchers find that brain cell regeneration may alleviate symptoms of Alzheimer's disease

Researchers find that brain cell regeneration may alleviate symptoms of Alzheimer's disease

Alzheimer's disease is the most widespread degenerative neurological disorder in the world. Over five million Americans live with it, and one in three senior citizens will die with the disease or a similar form of dementia. While memory loss is a common symptom of Alzheimer's, other behavioral manifestations - depression, loss of inhibition, delusions, agitation, anxiety, and aggression - can be even more challenging for victims and their families to live with. [More]
Scientists describes new advantageous way to detect different immune cells in the blood

Scientists describes new advantageous way to detect different immune cells in the blood

When a person becomes sick or is exposed to an unwelcome substance, the body mobilizes specific proportions of different immune cells in the blood. Methods of discovering and detecting those profiles are therefore useful both clinically and in research. In a new paper in the journal Genome Biology, a team of scientists describes a new and uniquely advantageous way to detect them. [More]
Research provides insight into biologic mechanisms that individual cancer cells use to metastasize to brain

Research provides insight into biologic mechanisms that individual cancer cells use to metastasize to brain

New research from Memorial Sloan Kettering provides fresh insight into the biologic mechanisms that individual cancer cells use to metastasize to the brain. [More]
Study provides novel insight into the impact of genes on Huntington's disease

Study provides novel insight into the impact of genes on Huntington's disease

A study led by researchers at Boston University School of Medicine provides novel insight into the impact that genes may have on Huntington's disease (HD). The study, published online in PLOS Genetics, identified specific small segments of RNA (called micro RNA or miRNA) encoded in DNA in the human genome that are highly expressed in HD. [More]
Increased brain cell activity boosts protein linked to Alzheimer's disease

Increased brain cell activity boosts protein linked to Alzheimer's disease

Increased brain cell activity boosts brain fluid levels of a protein linked to Alzheimer's disease, according to new research from scientists at Washington University School of Medicine in St. Louis. [More]
Researcher isolates gene thought to play role in development of Alzheimer's disease

Researcher isolates gene thought to play role in development of Alzheimer's disease

A team of international scientists, including a researcher from Simon Fraser University, has isolated a gene thought to play a causal role in the development of Alzheimer's disease. The Proceedings of the National Academy of Sciences recently published the team's study. [More]
Researchers discover how brain cells change during learning and memories

Researchers discover how brain cells change during learning and memories

A new University of British Columbia study identifies an important molecular change that occurs in the brain when we learn and remember. [More]
Deficiency in SNX27 explains learning impairment in Down's syndrome

Deficiency in SNX27 explains learning impairment in Down's syndrome

Scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) have identified the precise role of the protein, SNX27, in the pathway leading to memory and learning impairment. [More]
Scientists develop new paradigms for understanding how human brain works in health, disease

Scientists develop new paradigms for understanding how human brain works in health, disease

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to this challenge, we will gain profound insights into what makes us human, develop new treatments for brain diseases, and build revolutionary new computing technologies that will have far reaching effects, not only in neuroscience. [More]
Being overweight may cause changes in brain that is crucial to appetite, emotions and memory

Being overweight may cause changes in brain that is crucial to appetite, emotions and memory

Being overweight appears related to reduced levels of a molecule that reflects brain cell health in the hippocampus, a part of the brain involved in memory, learning, and emotions, and likely also involved in appetite control, according to a study performed by researchers at SUNY Downstate Medical Center and other institutions. [More]
Study points to gender-specific mechanisms of brain repair following oxygen deprivation

Study points to gender-specific mechanisms of brain repair following oxygen deprivation

Physicians have long known that oxygen deprivation to the brain around the time of birth causes worse damage in boys than girls. Now a study by researchers from the Johns Hopkins Children’s Center conducted in mice reveals one possible reason behind this gender disparity and points to gender-specific mechanisms of brain repair following such injury. [More]
New molecule could help lower diabetic patients' risk of developing dementia or Alzheimer's

New molecule could help lower diabetic patients' risk of developing dementia or Alzheimer's

Researchers at the Hebrew university of Jerusalem have created a molecule that could potentially lower diabetic patients' higher risk of developing dementia or Alzheimer's disease. [More]
New molecule reduces diabetic patients' higher risk of developing dementia, Alzheimer's

New molecule reduces diabetic patients' higher risk of developing dementia, Alzheimer's

​Researchers at the Hebrew university of Jerusalem have created a molecule that could potentially lower diabetic patients' higher risk of developing dementia or Alzheimer's disease. [More]
Exposure to pesticide may increase risk of Alzheimer's disease, say researchers

Exposure to pesticide may increase risk of Alzheimer's disease, say researchers

Scientists have known for more than 40 years that the synthetic pesticide DDT is harmful to bird habitats and a threat to the environment. [More]